A5003220890- Lichen and fungal ecology
- Health and Medical Studies
- Chronic Lymphocytic Leukemia Research
- Acute Myeloid Leukemia Research
- Lymphoma Diagnosis and Treatment
- Biomedical and Chemical Research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Immunodeficiency and Autoimmune Disorders
- CAR-T cell therapy research
- Cancer Immunotherapy and Biomarkers
- Medical Practices and Rehabilitation
- Medical and Health Sciences Research
- Chemical synthesis and alkaloids
- Immunotherapy and Immune Responses
- Medical History and Research
- Chemical Reactions and Mechanisms
- Genetic factors in colorectal cancer
- Acute Lymphoblastic Leukemia research
- Coordination Chemistry and Organometallics
- Monoclonal and Polyclonal Antibodies Research
- Psychology, Coaching, and Therapy
- Neutropenia and Cancer Infections
- History and advancements in chemistry
- German Social Sciences and History
- Advanced Breast Cancer Therapies
Otto-von-Guericke University Magdeburg
2013-2024
Fachhochschule Kiel
2023
Boehringer Ingelheim (Germany)
2023
Boehringer Ingelheim (Austria)
2021-2022
University Hospital Regensburg
2013-2018
University Hospital Cologne
2009-2016
GKV Spitzenverband
2016
Heidelberg University
1975-2014
University Hospital Heidelberg
2011-2014
University of Cologne
2009-2014
The authors measured opioid receptor-active components in the CSF of 11 women with postpartum psychosis, healthy lactating women, and 16 who were not lactating. Activity that eluted 0.2 M acetic acid 0.7-0.9 times total volume column (fraction II activity) was significantly higher both psychotic puerperium than women. Very high levels fraction activity seen four patients. Material from these patients further characterized by electrophoresis high-performance liquid chromatography: material...
Pentachlorophenol (PCP), hexachlorocyclohexane-[alpha], -beta, and -[gamma] (HCH-[alpha], -[gamma]), polychlorinated biphenyls (PCBs), hexachlorobenzene (HCB) are widely distributed industrial chemicals. They suspected to induce immunologic impairments in exposed individuals. We examined dose-response relationships of blood levels these chemicals with cellular (numbers lymphocyte subpopulations, vitro response) or humoral (plasma cytokine levels, immunoglobulin autoantibodies) dysfunctions....
Abstract Activation of the PI3K/PTEN signaling pathway down-regulates pro-inflammatory gene expression via up-regulation DUSP1. Resolution inflammation is an important hallmark in course infectious diseases. Dysregulated inflammatory responses may have detrimental consequences for affected organism. Therefore, tight regulation indispensable. Among numerous modulatory pathways, has been proposed recently to be involved innate immune reactions. Here, we attempted elucidate molecular mechanisms...
Abstract Die einfach ungesättigten Fettsäuren geben mit Benzopersäure, wie nach früheren Untersuchungen zu erwarten war, Oxydosäuren, aus denen durch Kochen Kalilauge die entsprechenden Dioxyfettsäuren erhalten werden. Mehrfach ungesättigte Fettsäuren, Linolsäure und Linolensäure α‐Eläostearinsäure, werden wohl ebenfalls oxydiert, aber Oxydationsprodukte liefern beim keine einfachen Polyoxyfettsäuren, sondern ölige Säuren, große Ähnlichkeit den Verseifung der Oxyne erhältlichen Oxynsäuren...
ABSTRACT To examine the effects of intrauterine growth restriction on nephron number, renal circulation, and excretory functions in newborns, studies were conducted 1‐day‐old anaesthetized piglets, divided into normal weight ( n = 6) restricted piglets. Renal blood flow was measured by coloured microspheres, glomerular filtration rate inulin clearance, osmotic clearance fractional sodium excretion calculated. In addition, an estimation number performed counting representative numbers...
Context. Seizures are a recognized complication of acute overdose with the racemic (1:1 ratio R- and S-enantiomers) selective serotonin reuptake inhibitor antidepressant citalopram. Objective. We tested hypothesis that escitalopram (the therapeutically active S‐enantiomer citalopram) causes fewer seizures in than citalopram at comparable doses S-enantiomer. Methods. Multicenter retrospective review cases reported to German, Austrian, Swiss Poisons Centers between 1997 2006. Results. 316 63...
Advanced-stage gastrointestinal cancers represent a high unmet need requiring new effective therapies. We investigated the antitumor activity of novel T cell-engaging antibody (B7-H6/CD3 ITE) targeting B7-H6, tumor-associated antigen that is expressed in tumors.Membrane proteomics and IHC analysis identified B7-H6 as tumor tissues with no to very little expression normal tissues. The mode action B7-H6/CD3 ITE was evaluated vitro coculture assays, humanized mouse models, colorectal cancer...