A5031907822- Neuropeptides and Animal Physiology
- Pain Mechanisms and Treatments
- Anesthesia and Pain Management
- Pediatric Pain Management Techniques
- Stress Responses and Cortisol
- Cardiac, Anesthesia and Surgical Outcomes
- Musculoskeletal pain and rehabilitation
- Fungal Infections and Studies
- Neurotransmitter Receptor Influence on Behavior
- Respiratory and Cough-Related Research
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Pharmacological Receptor Mechanisms and Effects
- Pneumocystis jirovecii pneumonia detection and treatment
- Airway Management and Intubation Techniques
- Botulinum Toxin and Related Neurological Disorders
- Cancer, Stress, Anesthesia, and Immune Response
- Nuclear Receptors and Signaling
- Apelin-related biomedical research
- Receptor Mechanisms and Signaling
- Heart Rate Variability and Autonomic Control
- Antifungal resistance and susceptibility
- Bee Products Chemical Analysis
Université de Sherbrooke
2011-2020
Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal
2020
Centre Hospitalier Universitaire de Sherbrooke
2020
Abstract Apelin is the endogenous ligand of APJ receptor, a member G‐protein‐coupled receptor family. The apelin–APJ complex has been detected in many tissues and emerging as promising target for several pathophysiological conditions. There currently little information on structure–activity relationship (SAR) apelin hormone. In an effort to better delineate SAR, we synthesized analogues apelin‐13 modified at selected positions with unnatural amino acids, particular emphasis C‐terminal...
The use of quantitative sensory testing (QST) in multicenter studies has been quite limited, due part to lack standardized procedures among centers.The aim this study was assess the application capsaicin pain model as a surrogate experimental human neuropathic different centers and verify variation reports QST measures across centers.A conducted by Quebec Pain Research Network six laboratories allowed evaluation nine parameters 60 healthy subjects treated with topical unilateral allodynia....
Neurotensin (NT) is a tridecapeptide displaying interesting antinociceptive properties through its action on receptors, NTS1 and NTS2. Neurotensin-like compounds have been shown to exert better than morphine at equimolar doses. In this article, we characterized the molecular effects of novel neurotensin (8-13) (NT(8-13)) analog containing an unnatural amino acid. This compound, named JMV2009, displays Silaproline in position 10 replacement proline native NT(8-13). We first examined binding...
Introduction The purpose of the present study was to investigate if preoperative concentrations monoamine neurotransmitters that are known be involved in descending pain modulation associated with perioperative intensity a pediatric cohort patients idiopathic scoliosis scheduled for elective spinal fusion surgery. Material and Methods Patients undergo surgery Adolescent Idiopathic Scoliosis (AIS) between ages 12 18 years were recruited from outpatient clinic Shriners Hospital Children ( n =...