- Pediatric Pain Management Techniques
- Anesthesia and Pain Management
- Anesthesia and Sedative Agents
- Anesthesia and Neurotoxicity Research
- Cardiac, Anesthesia and Surgical Outcomes
- Musculoskeletal pain and rehabilitation
- Pain Management and Opioid Use
- Intensive Care Unit Cognitive Disorders
- Nausea and vomiting management
- Pain Mechanisms and Treatments
- Airway Management and Intubation Techniques
- Spine and Intervertebral Disc Pathology
- Shoulder Injury and Treatment
- Spaceflight effects on biology
- Telemedicine and Telehealth Implementation
- Infant Development and Preterm Care
- Neonatal Respiratory Health Research
- Enhanced Recovery After Surgery
- Gastroesophageal reflux and treatments
- Neuropeptides and Animal Physiology
- Intraocular Surgery and Lenses
- Pain Management and Placebo Effect
- Cancer, Stress, Anesthesia, and Immune Response
- Clinical Nutrition and Gastroenterology
- Hemodynamic Monitoring and Therapy
McGill University
2015-2025
McGill University Health Centre
2014-2025
Montreal Children's Hospital
2016-2025
Concordia University
2025
Society for Pediatric Anesthesia
2024
GTx (United States)
2024
Hôpital d'Enfants
2022
American Association of Nurse Practitioners
2020
Consorzio Interuniversitario Reattività Chimica e Catalisi
2019
Shriners Hospitals for Children - Canada
2018
Summary Objectives/Aim This randomized control trial was designed to evaluate the incidence of emergence delirium ( ED ) in preschool children receiving sevoflurane or desflurane anesthesia combined with an effective caudal block. Background While has been described anesthesia, a direct comparison between two agents using validated assessment tool not reported previously. Methods/Materials Two hundred and sixty scheduled for elective sub‐umbilical surgery were receive defined as Paediatric...
Summary Background Early negative postoperative behavior (e‐ PONB ) is common in children and manifests itself as emergence agitation ( EA ), delirium ED pain. The objective of this prospective double blind, randomized, placebo‐controlled trial was to determine whether IV clonidine or fentanyl prior surgery modifies e‐ children. Methods Ninety scheduled for subumbilical under sevoflurane anesthesia supplemented with regional were randomized either receive 2 mcg·kg −1 , placebo saline) before...
Summary Background Children commonly display early postoperative negative behavior (e‐ PONB ) after general anesthesia, which includes emergence delirium ( ED ), discomfort, temperament, and pain. However, it is often difficult for the caregiver to discriminate between various aspects of e‐ . Objective This prospective observational study evaluates possibility distinguish pain in young children using validated pediatric scales phase. Methods Following institutional approval written consent,...
Pain in lower back is a common condition reported by astronauts, both during and after space missions. Investigating the alterations spine mechanisms driving these changes essential for deeper understanding of how microgravity impacts human spine. This knowledge could also open pathways therapeutic or preventive interventions. Nevertheless, there limited evidence regarding intervertebral discs (IVDs) due to travel. In this study, 2 astronauts were enrolled Before flight, magnetic resonance...
Chronic pain in pediatric populations presents a multifaceted challenge with biopsychosocial impact, requiring multidisciplinary approach including psychological treatment. At our interdisciplinary center, the SARS-CoV-2 pandemic-related disruptions led to cessation of cognitive-behavioral therapy (CBT) and other interventions during pandemic. The aim this retrospective cohort study secondary matched case-control analysis was evaluate impact interruption non-CBT interventions, namely...
Objectives . Acute pain trajectories are associated with long-term outcomes such as persistent and functional disability in adults. However, there limited data on acute postoperative the pediatric population. The aims of this study were to investigate trajectories, their predictors, impact long- term adolescents idiopathic scoliosis. Methods We evaluated preoperative intensity, use analgesics, psychosocial measures physical functioning scheduled undergo spinal fusion, average 6-hour...
This study is aimed at assessing the psychometric properties and factorial structure of Pittsburgh Sleep Quality Index (PSQI) in a clinical sample children, adolescents, young adults with chronic pain. Data 482 participants (aged 8-21 years) from two crosssectional studies pain services outpatient clinic were analyzed. Exploratory confirmatory factor analysis reliability PSQI component scores performed. Relationships between global score various measures investigated to assess external...
Abstract The pathophysiology of fibromyalgia syndrome (FMS) remains elusive, leading to a lack objective diagnostic criteria and targeted treatment. We globally evaluated immune system changes in FMS by conducting multiparametric flow cytometry analyses peripheral blood mononuclear cells identified natural killer (NK) cell decrease patients with FMS. Circulating NK were exhausted yet activated, evidenced lower surface expression CD16, CD96, CD226 more CD107a TIGIT. These hyperresponsive,...
Summary Background: This randomized, double‐blind controlled trial was conducted to determine whether the association of sevoflurane for induction and isoflurane anesthesia maintenance resulted in a lower incidence postoperative agitation compared with as single agent. Methods: After Institute Ethics Committee's approval parental written informed consent, 128 unpremedicated children (1–6 years), ASA I‐II, scheduled elective subumbilical surgery were enrolled. 8% sevoflurane, patients...
In Brief BACKGROUND: Studies evaluating intraperitoneal local anesthetic instillation for pain relief after laparoscopic procedures have reported conflicting results. this randomized, double-blind study we assessed the effects of nebulization on cholecystectomy. METHODS: Patients undergoing elective cholecystectomy were randomly assigned to receive either ropivacaine 0.5%, 20 mL induction pneumoperitoneum, or 1%, 3 before and surgery. Anesthetic surgical techniques standardized. Degree at...
Abstract Systemic inflammation participates to the complex healing process occurring after major surgery, thus directly affecting surgical outcome and patient recovery. Total plasma N-glycome might be an indicator of as well anti-inflammatory therapy response marker, since protein glycosylation plays essential role in inflammatory cascade. Therefore, we assessed effects surgery on total association with self-administration postoperative morphine two cohorts patients that underwent abdominal...
A major limitation in treatment outcomes for chronic pain is the heterogeneity of population. Therefore, a personalized approach to assessment and children adolescents with conditions needed. The objective study was subgroup pediatric patients MSK that will be phenotypically different from each other based on their psychosocial profile, somatosensory function, modulation.This observational cohort recruited 302 (10-18 years) musculoskeletal 80 age-matched controls. After validated self-report...
Summary Background: The laryngeal tube (LT) is a supraglottic ventilatory device used in adults. However, there limited information about LT use pediatric patients. This randomized controlled study compares with mask (LMA) for airway management during spontaneous or assisted ventilation and fiberoptic laryngoscopy children. Methods: Thirty children under 10‐years old, ASA I–II, scheduled minor general surgery, Mallampati score fasted premedicated were included. Patients upper respiratory...