A5017105181- Scientific Computing and Data Management
- Research Data Management Practices
- Genetics, Bioinformatics, and Biomedical Research
- Biomedical Text Mining and Ontologies
- Cell Image Analysis Techniques
- Distributed and Parallel Computing Systems
- RNA Research and Splicing
- Plant Pathogens and Fungal Diseases
- Meta-analysis and systematic reviews
- RNA modifications and cancer
- RNA regulation and disease
- Microbial Community Ecology and Physiology
- Cell Adhesion Molecules Research
- Health, Environment, Cognitive Aging
- Architecture and Computational Design
- Intracranial Aneurysms: Treatment and Complications
- Machine Learning and Data Classification
- scientometrics and bibliometrics research
- Data Stream Mining Techniques
- Diversity and Career in Medicine
- Cancer-related molecular mechanisms research
- Environmental DNA in Biodiversity Studies
- Medicinal Plant Extracts Effects
- Botanical Research and Applications
- Horticultural and Viticultural Research
China Science and Technology Publishing & Media
2016-2024
GigaScience Press
2022-2023
Heidelberg University
2011-2012
Abstract Biomedical research depends increasingly on computational tools, but mechanisms ensuring open data, software, and reproducibility are variably enforced by academic institutions, funders, publishers. Publications may present software for which source code or documentation become unavailable; this compromises the role of peer review in evaluating technical strength scientific contribution. Incomplete ancillary information an package bias limit subsequent work. We provide 8...
Data-driven computational analysis is becoming increasingly important in biomedical research, as the amount of data being generated continues to grow. However, lack practices sharing research outputs, such data, source code and methods, affects transparency reproducibility studies, which are critical advancement science. Many published studies not reproducible due insufficient documentation, code, shared. We conducted a comprehensive 453 manuscripts between 2016–2021 found that 50.1% them...
In the era of computation and data-driven research, traditional methods disseminating research are no longer fit-for-purpose. New approaches for data, results required to maximize knowledge discovery. The "long tail" small, unstructured datasets is well catered by a number general-purpose repositories, but there has been less support "big data". Outlined here our experiences in attempting tackle gaps publishing large-scale, computationally intensive research. GigaScience an open-access,...
Zinc finger motif-1 (ZFM1) represses proinflammatory gene expression in vascular smooth muscle cells (SMCs) at a global level and thus may also be involved the attenuation of growth factor-induced phenotype changes these cells. Using human primary cultured thymus vein SMCs, we have investigated molecular mechanism by which potent SMC mitogen, platelet-derived factor-BB (PDGF-BB), causes rapid decrease ZFM1 concentration-dependent manner consequences thereof. Reporter analyses chromatin...
<strong> The 9th Women in Science Conference took place Shenzhen. Below are some highlights from the conference co-organized by our Publishing Director, Laurie Goodman, and Co-Chaired Doris Yang, BGI-College. </strong> Today,&nbsp; March 8, 2024 marks International Women’s Day – where women’s achievement inclusivity is celebrated.
Throughout the last 15 years, concept of replacing deficient genes or knocking down expression that cause disease has been consistently developed and is under scrutiny by public. This known as gene therapy. Several strategies therapy have developed, ranging from use retroviral vectors carrying a interest whose aim to re-insert into patient genome, DNA technology inhibit target expression. In particular, application technology, such RNA interference antisense strategies, silence regulate...
Abstract Data-driven computational analysis is becoming increasingly important in biomedical research, as the amount of data being generated continues to grow. However, lack practices sharing research outputs, such data, source code and methods, affects transparency reproducibility studies, which are critical advancement science. Many published studies not reproducible due insufficient documentation, code, shared. We conducted a comprehensive 453 manuscripts between 2016-2021 found that...
<strong> Cheering Ourselves up with CUDDEL(s) and Hackathons </strong> We have been working closely the Metabolomics community for a few years now, participating in hackathon events including BYO Data parties Hack-the-Spec – ISA as FAIR research object thanks to our collaboration Team at Oxford e-Research Centre funding from BBSRC UK-China partnering award.
When it comes to technology, <em> GigaScience </em> has always been open and willing embrace new ways of integrating technology in its publishing processes, with the ultimate goal working towards more reproducible, interactive executable papers.
<strong> <em> What does Neuroinformatics and The Great Barrier Reef have in Common? Both are faced with challenges comprise of beautiful colourful entities that should be freely accessible shared. </em> </strong> This year’s International Coordinating Facility (INCF) 2015 meeting was held the northern tropical Queensland city Cairns, Australia.
<strong> Editors: Mark Wass (University of Kent, UK), Iddo Friedberg (Miami University, Oxford, Ohio, USA), Predrag Radivojac (Indiana Bloomington, Indiana, USA) </strong> <b> </b> A key to understanding life at the molecular level is based on accurate protein annotation functional level.
The genomics community has been held up as an exemplar in data sharing practices since the human genome project, but metabolomics is catching fast, with Metabolights database being fast growing repository at EBI.
Last Christmas we gave you our heart; okay forget George Michael – beautiful imaging data sets, Virtual Machines, BYO parties, GigaGitHub, more open peer review plus much more.
Forget Movember – with all the cool open brain science activities happening at <em> GigaScience </em> and upcoming Society for Neuroscience (SfN) 2016 meeting in San Diego (November 12-16), we are naming it Neuro-November!
Tītitipounamu, Rifleman, female (left) and male (right) <b> Our New Zealand based Commissioning Editor, Nicole Nogoy, was asked by Creative Commons Aotearoa (New Zealand) to write a guest blog on open licensing from Kiwi perspective. Being big users fans of their licenses we were happy oblige. </b>
Taylor Noble As the ecology community expands, it is now adopting new ways of making sense plethora data produced from diverse approaches, including ocean research, eco-genomics, limnology, and macrosystems ecology, through more integrative means – improving our understanding biology in a broader sense.
<em> In support of Brain Awareness Week, we have asked Cameron Craddock, Director the Computational NeuroImaging Lab, Nathan S. Kline Institute for Psychiatric Research and Imaging, Child Mind Institute, to write a blog highlighting open science in neuroimaging, announce our upcoming publication 2015 Brainhack Proceedings Thematic Series. </em>
<strong> Shedding light on what the Optical Mapping System can provide for genome analysis, here we present a guest posting from optical mapping pioneer and developer (and <em> GigaScience </em> Editorial Board Member), David C. Schwartz, who is Professor of Chemistry Genetics at University Wisconsin-Madison. </strong> Taking Google Maps approach: providing comprehensive, scalable worldviews We use maps in our
<b> Following our efforts encouraging open-science projects, such as the community funded “Peoples Parrot” and OpenAshDieback, today we have a guest posting from Fay-Wei Li Kathleen Pryer Department of Biology at Duke University covering crowdfunding effort to sequence <i> Azolla </i> genome. </b>