A5020452511- Natural Antidiabetic Agents Studies
- Cancer-related molecular mechanisms research
- Computational Drug Discovery Methods
- MicroRNA in disease regulation
- Pharmacological Effects of Natural Compounds
- Pancreatic function and diabetes
- Circular RNAs in diseases
- Oral Health Pathology and Treatment
- PARP inhibition in cancer therapy
- Andrographolide Research and Applications
Saveetha University
2024
Ragas Dental College & Hospital
2022-2024
This review explores MicroRNAs' (miRNAs) role in Oral Submucous Fibrosis (OSMF) malignant transformation. OSMF, a potentially life-threatening disorder, exhibits 7.6% to 13% probability of MiRNAs like miR-21 and miR-29b play crucial roles OSMF pathogenesis, affecting fibrosis malignancy. Their dysregulation impacts TGF-/Smad Wnt/-catenin signaling pathways, contributing fibrotic alterations. transformation involves genetic epigenetic changes, with miR-34 miR-1246 implicated increased cell...
Diabetes mellitus is a group of metabolic disorders that has risen to become the third most common cause in humans recent years. The development new bioactive substances from natural sources relatively area. Flavonoids are believed have variety beneficial properties nature, including anti-inflammatory, antimicrobial, anticancer, antioxidant, neuroprotective, and anti-HIV properties. 15 naturally occurring flavonoids docked with selected target aldose reductase. We report optimal binding...
Natural remedies from medicinal plants are known to be effective and reliable appropriate medicine for illnesses. The current research examined Plectranthus amboinicus' anti diabetic property by docking the bioactive compounds of certain target proteins. We document molecular analysis amboinicus with protein Glucokinase. Molecular experiments were carried out in PyRx software. Results these showed that most very strong interaction Based on scoring parameters we have selected best four...
We document the Molecular docking analysis of bioactive compounds from