A5023565234- Pancreatic and Hepatic Oncology Research
- Computational Drug Discovery Methods
- Probiotics and Fermented Foods
- Gut microbiota and health
- Bioinformatics and Genomic Networks
- Advanced Proteomics Techniques and Applications
- Cancer Genomics and Diagnostics
- Machine Learning in Bioinformatics
- Gene expression and cancer classification
- Ferroptosis and cancer prognosis
- Cancer Cells and Metastasis
- Genomics and Phylogenetic Studies
- Protein Hydrolysis and Bioactive Peptides
- Nuclear Receptors and Signaling
- Nutrition, Genetics, and Disease
- Macrophage Migration Inhibitory Factor
- Biochemical effects in animals
- Tryptophan and brain disorders
- Cancer Research and Treatments
- Advanced Chemical Sensor Technologies
- Diet and metabolism studies
- Microbial Metabolites in Food Biotechnology
- CAR-T cell therapy research
- Diverse Scientific Research Studies
- Metabolomics and Mass Spectrometry Studies
Saveetha University
2022-2025
Korea University
2016-2025
Yenepoya University
2025
Bharathidasan University
2010-2022
Kaohsiung Medical University
2021-2022
Aligarh Muslim University
2022
Amrita Vishwa Vidyapeetham
2022
Kangwon National University
2021
Central University of South Bihar
2021
Wolaita Sodo University
2021
The present study investigated the involvement of human papillomavirus (HPV)16 and HPV18 in oropharyngeal malignancies order to understand oncogenic mechanisms, identify biomarkers for early detection treatment targets. Given rising incidence HPV-associated cancer, particularly India, this holds significance elucidating molecular basis these diseases. Structural validation HPV16 18 oncoproteins E6 E7 was conducted using computational tools, while gene expression profiles related oral...
The RNA cytosine C(5)-methyltransferase NSUN2 is involved in modification and regulates gene expression genomic stability. Beyond multiple sequence/copy number variations, displays altered phosphoprotein various cancers developmental disorders, thereby making it a prime molecular target of relevance to both therapeutics diagnostics, that is, theranostics. Despite its key role kinase-regulated pathways broader biological processes, the phospho-regulatory network remains largely unexplored. We...
Alzheimer's Disease (AD) is one of the most common causes dementia, mostly affecting elderly population. Currently, there no proper diagnostic tool or method available for detection AD. The present study used two distinct data sets AD genes, which could be potential biomarkers in diagnosis. differentially expressed genes (DEGs) curated from both datasets were machine learning classification, tissue expression annotation and co-expression analysis. Further, CNPY3, GPR84, HIST1H2AB, HIST1H2AE,...
Alzheimer's Disease (AD) is one of the most common causes dementia, mostly affecting elderly population. Currently, there no proper diagnostic tool or method available for detection AD. The present study used two distinct data sets AD genes, which could be potential biomarkers in diagnosis. differentially expressed genes (DEGs) curated from both datasets were machine learning classification, tissue expression annotation and co-expression analysis. Further, CNPY3, GPR84, HIST1H2AB, HIST1H2AE,...
This review explores MicroRNAs' (miRNAs) role in Oral Submucous Fibrosis (OSMF) malignant transformation. OSMF, a potentially life-threatening disorder, exhibits 7.6% to 13% probability of MiRNAs like miR-21 and miR-29b play crucial roles OSMF pathogenesis, affecting fibrosis malignancy. Their dysregulation impacts TGF-/Smad Wnt/-catenin signaling pathways, contributing fibrotic alterations. transformation involves genetic epigenetic changes, with miR-34 miR-1246 implicated increased cell...
Smoking is the leading cause of lung cancer development and several genes have been identified as potential biomarker for lungs cancer. Contributing to present scientific knowledge biomarkers two different data sets, i.e. GDS3257 GDS3054 were downloaded from NCBI׳s GEO database normalized by RMA GRMA packages (Bioconductor). Diffrentially expressed extracted using R (3.1.2); DAVID online tool was used gene annotation GENE MANIA construction regulatory network. Nine smoking independent found...
Mass spectrometry (MS)-based proteomics, which uses high-resolution hybrid mass spectrometers such as the quadrupole-orbitrap spectrometer, can yield tens of thousands tandem (MS/MS) spectra high resolution during a routine bottom-up experiment. Despite being fundamental and key step in MS-based accurate determination assignment precursor monoisotopic masses to MS/MS remains difficult. The difficulties stem from imperfect isotopic envelopes ions, inaccurate charge states for cofragmentation....
Breast Cancer is the most predominant form of cancer among women worldwide. It has been rigorously studied for biomarker identifications and therapeutic targets. However, various potential genes their clinical relevance to breast remain unexplored. The heterogeneity one major challenges in early detection. Several studies have reported significant role alkaline phosphate (ALP) regulation tumor growth overall free survival pathogenesis different cancer, including which may offer unique...
// Hussain Al Ssadh 1 , Patrick S. Spencer Waleed Alabdulmenaim 1, 2 Rana Alghamdi 3 Inamul Hasan Madar 4 Jose M. Miranda-Sayago and Nelson Fernández School of Biological Sciences, University Essex, Wivenhoe Park, Colchester, Essex CO4 3SQ, United Kingdom Pathology Department, College Medicine, Qassim University, Qassim, Saudi Arabia King Abdulaziz Rabigh Campus, Rabigh, Department Biotechnology Genetic Engineering, Bharathidasan Tiruchirappalli, 620024, Tamil Nadu, India Correspondence to:...
The cluster of differentiation (CD) 74 is known for its immunological functions and elevated level was reported in various cancer cells.The aim the present study to investigate expression potential roles CD74 proliferative apoptotic activity breast cancer.Expression CD74, macrophage migration inhibitory factor (MIF) CD44 assayed CAMA-1 MDA-MB-231 cell lines using flow cytometry. knocked down siRNA-transfection CAMA-1, cells proliferation apoptosis were determined transfected data showed that...
• CRISPR technology revolutionizes gene editing, offering hope for curing genetic and complex diseases. Modified cas9 enzyme enables activation or repression, expanding CRISPR's therapeutic applications. role in cancer treatment includes innovative immunotherapies precise targeting. Experimental therapies like NY-ESO1 method demonstrate progress cancer-specific T cell modification. Challenges delivery safety are being addressed to unlock its full potential.
Polycystic ovary syndrome (PCOS) is endocrine system disease which affect women ages 18 to 44 where the women's hormones are imbalance. Recently it has been reported occur in early age. Alteration of normal gene expression PCOS shown negative effects on long-term health issues. responsible factor for infertility reproductive age group. Early diagnosis and treatment can improve suffering from PCOS. Earlier Studies shows correlation upon insulin resistance with significant outcome, Current...