A5056940950- Immune Cell Function and Interaction
- Viral-associated cancers and disorders
- Enzyme Catalysis and Immobilization
- Fermentation and Sensory Analysis
- RNA modifications and cancer
- Immunotherapy and Immune Responses
- Nicotinic Acetylcholine Receptors Study
- Ion Channels and Receptors
- Enzyme-mediated dye degradation
- Genomics and Chromatin Dynamics
- T-cell and Retrovirus Studies
- Ion channel regulation and function
- Horticultural and Viticultural Research
- T-cell and B-cell Immunology
- DNA Repair Mechanisms
- Carcinogens and Genotoxicity Assessment
Universidad de Valladolid
2023
Instituto de Biomedicina y Genética Molecular de Valladolid
2018
Consejo Superior de Investigaciones Científicas
2018
Rockefeller University
2011-2015
The Aicda gene encodes Activation-Induced cytidine Deaminase (AID), an enzyme essential for remodeling antibody genes in mature B lymphocytes. AID is also responsible DNA damage at oncogenes, leading to their mutation and cancer-associated chromosome translocation lymphoma. We used fate mapping AIDGFP reporter mice determine if expression the mouse extends beyond discovered that AIDcre tags a small fraction of non-lymphoid cells starting 10.5 days post conception (dpc), AIDGFP+ are...
Higher temperatures due to climate change are causing greater sugar production in grapes and more alcoholic wines. The use of glucose oxidase (GOX) catalase (CAT) grape must is a biotechnological green strategy produce reduced-alcohol GOX CAT were effectively co-immobilized by sol-gel entrapment silica-calcium-alginate hydrogel capsules. optimal co-immobilization conditions achieved at concentration the colloidal silica, sodium silicate alginate 7.38%, 0.49% 1.51%, respectively, pH 6.57....
Glucose oxidase (GOX) and catalase (CAT) were co-immobilized in silica-calcium-alginate hydrogels to degrade must glucose. The effect of the enzyme dose (1.2-2.4 U/mL), initial pH (3.6-4.0), incubation temperature (10-20 °C) on glucose consumption, gluconic acid concentration, pH, color intensity Verdejo was studied by using a Box-Behnken experimental design comparing free enzymes. A reduction up 37.3 g/L observed enzyme-treated must, corresponding decrease its potential alcohol strength...