A5065049889- Gastric Cancer Management and Outcomes
- Colorectal Cancer Screening and Detection
- Esophageal and GI Pathology
- Colorectal Cancer Surgical Treatments
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Gastrointestinal disorders and treatments
- Dysphagia Assessment and Management
- Peripheral Artery Disease Management
- Aortic aneurysm repair treatments
- Tracheal and airway disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cardiovascular Health and Disease Prevention
- Gastroesophageal reflux and treatments
- Radiomics and Machine Learning in Medical Imaging
- Diverticular Disease and Complications
- Helicobacter pylori-related gastroenterology studies
- Pancreatic and Hepatic Oncology Research
- Cardiac, Anesthesia and Surgical Outcomes
- Eosinophilic Esophagitis
- Esophageal Cancer Research and Treatment
- Disaster Response and Management
- Gallbladder and Bile Duct Disorders
- Rock Mechanics and Modeling
- Lung Cancer Treatments and Mutations
The University of Sydney
2021-2025
Westmead Hospital
2021-2025
RELX Group (Netherlands)
2024
Northern Health
2024
Geelong Hospital
2018-2019
St Vincent's Hospital
2015-2018
Creative Research Enterprises (United States)
2018
James Cook University
2012-2015
Townsville Hospital
2013
Background and aims Conventional hot snare endoscopic mucosal resection (H-EMR) is effective for the management of large (≥20 mm) non-pedunculated colon polyps (LNPCPs) however, electrocautery-related complications may incur significant morbidity. With a superior safety profile, cold EMR (C-EMR) LNPCPs an attractive alternative however evidence lacking. We conducted randomised trial to compare efficacy C-EMR H-EMR. Methods Flat, 15–50 mm adenomatous were prospectively enrolled randomly...
Non-lifting large non-pedunculated colorectal polyps (NL-LNPCPs) account for 15% of LNPCP and are effectively managed by Endoscopic Mucosal Resection with adjunctive Cold-forceps Avulsion adjuvant Snare-Tip soft coagulation (CAST). However, recurrence rates > 10% at surveillance colonoscopy is a significant limitation. We aimed to compare the outcomes CAST MTA versus alone NL-LNPCPs. Prospective observational data on consecutive patients NL-LNPCPs treated EMR single tertiary center was...
Abstract Background Recognition of submucosal invasive cancer (SMIC) in large (≥20 mm) nonpedunculated colonic polyps (LNPCPs) informs selection the optimal resection strategy. LNPCP location, morphology, and size influence risk SMIC; however, currently no meaningful application this information has simplified process to make it accessible broadly applicable. We developed a decision-making algorithm simplify identification subtypes with increased potential SMIC. Methods Patients referred for...
Lesion size is an independent risk factor for recurrence following endoscopic mucosal resection of large (≥20 mm) non-pedunculated colorectal polyps. Post-resection margin thermal ablation (MTA) reduces the recurrence. Its impact on uncommon larger (≥40 lesions unknown. We sought to analyse MTA ≥40 mm in a large, prospective cohort. A cohort patients with polyps ≥20 treated piecemeal expert tissue centre was divided into three phases: 'pre-MTA', July 2009-June 2012; 'MTA-adoption', 2012-June...
Abstract Background Non-achalasia esophageal motility disorders (NAEMDs), encompassing distal spasm (DES) and hypercontractile esophagus (HCE), are rare conditions. Peroral endoscopic myotomy (POEM) is a promising treatment option. In NAEMDs, unlike with achalasia, the lower sphincter (LES) functions normally, suggesting potential of LES preservation during POEM. Methods This retrospective two-center observational study focused on patients undergoing LES-preserving POEM (LES-POEM) for NAEMD....
The efficacy of colorectal endoscopic mucosal resection (EMR) is limited by recurrence and the necessity for conservative surveillance. Margin thermal ablation (MTA) after EMR has reduced incidence at first surveillance colonoscopy 6 months (SC1). Whether this effect durable to second (SC2) unknown. We evaluated long-term outcomes in a cohort LNPCPs that have undergone MTA.
Colorectal strictures related to endoscopic resection (ER) of large nonpedunculated colorectal polyps (LNPCPs) may be problematic. Data on prevalence, risk factors, and management are limited. We report a prospective study following ER describe our approach management.We analyzed prospectively collected data over 150 months, until June 2021, for patients who underwent LNPCPs ≥ 40 mm. The defect size was graded as < 60 %, %-89 or 90 % the luminal circumference. Strictures were considered...
Previous studies in rodent models and patients suggest that visceral adipose could play a direct role the development progression of abdominal aortic aneurysm (AAA). This study aimed to assess association adiposity with AAA presence growth. was case-control investigation did (n=196) not (n=181) have an who presented The Townsville Hospital vascular clinic between 2003 2012. Cases were (infra-renal diameter >30 mm) controls intermittent claudication but no <30 mm). All underwent computed...
Abstract Background Large (≥20mm) adenomatous anastomotic polyps (LAAPs) are uncommon. Data pertaining to their prevalence, characteristics, and the efficacy of endoscopic resection (ER) absent. A safe effective strategy for ER would reduce morbidity healthcare costs. Methods nonpedunculated colorectal ≥20mm (LNPCPs) referred were prospectively studied. Multiple data points recorded including location, polyp morphology, modality, complications, technical success. Results Over 7 years until...