- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Colorectal Cancer Screening and Detection
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Gastrointestinal disorders and treatments
- Colorectal Cancer Surgical Treatments
- Esophageal Cancer Research and Treatment
- Mechanical Circulatory Support Devices
- Dysphagia Assessment and Management
- Plant Pathogens and Fungal Diseases
- Cardiac Structural Anomalies and Repair
- Lung Cancer Treatments and Mutations
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Diverticular Disease and Complications
- Gastroesophageal reflux and treatments
- Tracheal and airway disorders
- Anesthesia and Pain Management
- Gallbladder and Bile Duct Disorders
- Cardiac pacing and defibrillation studies
- Lung Cancer Diagnosis and Treatment
- Helicobacter pylori-related gastroenterology studies
- Meningioma and schwannoma management
- Cardiac Valve Diseases and Treatments
- Pancreatic and Hepatic Oncology Research
Westmead Hospital
2014-2025
The University of Sydney
2015-2025
St. Michael's Hospital
2024-2025
Westmead Institute
2023-2025
University of Toronto
2025
Diabetes Care and Research Foundation
2019-2024
RELX Group (Netherlands)
2024
Gallipoli Medical Research Foundation
2022
Princess Alexandra Hospital
2022
The University of Queensland
2022
Background and aims Conventional hot snare endoscopic mucosal resection (H-EMR) is effective for the management of large (≥20 mm) non-pedunculated colon polyps (LNPCPs) however, electrocautery-related complications may incur significant morbidity. With a superior safety profile, cold EMR (C-EMR) LNPCPs an attractive alternative however evidence lacking. We conducted randomised trial to compare efficacy C-EMR H-EMR. Methods Flat, 15–50 mm adenomatous were prospectively enrolled randomly...
Objective To evaluate the risk factors for lymph node metastasis (LNM) after a non-curative (NC) gastric endoscopic submucosal dissection (ESD) and to validate eventually refine eCura scoring system in Western setting. Also, assess rate parietal residual disease. Design Retrospective multicentre multinational study of prospectively collected registries from 19 centres. Patients who had been submitted surgery or at least one follow-up endoscopy were included. The was applied its accuracy...
The study was designed to examine a new method of confirming proper caudal needle placement using nerve stimulation.Thirty-two pediatric patients were studied. A 22-gauge insulated inserted into the canal via sacral notch until "pop" felt. classified as correct or incorrect depending upon presence absence anal sphincter contraction (S2-S4) electrical simulation (1 10 mA).Three excluded, two because they inadvertently received neuromuscular blockers and one patient's anatomy precluded any...
Abstract Background Recognition of submucosal invasive cancer (SMIC) in large (≥20 mm) nonpedunculated colonic polyps (LNPCPs) informs selection the optimal resection strategy. LNPCP location, morphology, and size influence risk SMIC; however, currently no meaningful application this information has simplified process to make it accessible broadly applicable. We developed a decision-making algorithm simplify identification subtypes with increased potential SMIC. Methods Patients referred for...
Abstract Background Non-achalasia esophageal motility disorders (NAEMDs), encompassing distal spasm (DES) and hypercontractile esophagus (HCE), are rare conditions. Peroral endoscopic myotomy (POEM) is a promising treatment option. In NAEMDs, unlike with achalasia, the lower sphincter (LES) functions normally, suggesting potential of LES preservation during POEM. Methods This retrospective two-center observational study focused on patients undergoing LES-preserving POEM (LES-POEM) for NAEMD....
Non-lifting large non-pedunculated colorectal polyps (NL-LNPCPs) account for 15% of LNPCP and are effectively managed by Endoscopic Mucosal Resection with adjunctive Cold-forceps Avulsion adjuvant Snare-Tip soft coagulation (CAST). However, recurrence rates > 10% at surveillance colonoscopy is a significant limitation. We aimed to compare the outcomes CAST MTA versus alone NL-LNPCPs. Prospective observational data on consecutive patients NL-LNPCPs treated EMR single tertiary center was...
Introduction Post-endoscopic resection (ER) management of high-risk T1 esophageal adenocarcinoma (EAC) is debated, with conflicting reports on lymph node metastases (LNM) We aimed to assess outcomes following radical ER for EAC. Methods identified patients who underwent (tumor-negative deep margin) EAC, followed by surgery or endoscopic surveillance, between 2008-2019 across 11 international centers. Results In total, 106 (86 men, 70 ±11 years) were included. Of these, 26 (64 yrs) additional...
Abstract Introduction and objectives Endoscopic ampullectomy is the preferred treatment for selected periampullary lesions, yet up to 10.6% of patients may experience delayed bleeding post‐procedure. This study aims identify predictors bleeding, which remain poorly understood. Methods was a single‐center retrospective cohort adult who underwent endoscopic (EA) between January 2011 September 2023. The primary outcome risk factors defined as post‐procedural that necessitated either an...
Abstract Large non-pedunculated colorectal polyps ≥20 mm (LNPCPs) constitute approximately 1% of all and present a spectrum risks, including overt covert submucosal invasive cancer (T1 (CRC)). Importantly, curative resection may be achieved for LNPCPs with superficial T1 CRC (T1a or T1b <1000 µm into submucosa), if an enbloc R0 excision (clear margins) favourable histology is (ie, absence high-grade tumour budding, lympho-vascular invasion, poor differentiation). Thus, while consensus...
A 26-year-old man sustained significant traumatic thoracoabdominal injuries following a gunshot. After multiple laparotomies, small-bowel resections, and an extended left hemicolectomy with end-colostomy formation, he developed high-output enterocutaneous fistula (ECF) loss of colostomy output. Computed tomography imaging confirmed ECF from the ileum to anterior abdominal wall. There was also long ileal stricture distal fistula. Owing his complex surgical abdomen proximity flap,...