- Antibiotic Resistance in Bacteria
- Nosocomial Infections in ICU
- Antibiotics Pharmacokinetics and Efficacy
- Pneumonia and Respiratory Infections
- Antibiotic Use and Resistance
- Occupational Health and Performance
- Congenital Diaphragmatic Hernia Studies
- Infectious Diseases and Tuberculosis
- Vascular Anomalies and Treatments
- COVID-19 Clinical Research Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Tracheal and airway disorders
- Abdominal Trauma and Injuries
- Blood disorders and treatments
- COVID-19 diagnosis using AI
- Body Composition Measurement Techniques
- Pancreatic and Hepatic Oncology Research
- Pneumothorax, Barotrauma, Emphysema
- Genetic and Kidney Cyst Diseases
- Extracellular vesicles in disease
- Sarcoidosis and Beryllium Toxicity Research
- Tuberous Sclerosis Complex Research
- Livestock and Poultry Management
- Medical Imaging and Pathology Studies
- Microbial Inactivation Methods
Taiwan Livestock Research Institute
2025
National Defense Medical Center
2014-2024
Tri-Service General Hospital
2014-2024
Hualien Armed Forces General Hospital
2021
Hypertriglyceridemia is the third most common cause of acute pancreatitis, but whether level triglyceride (TG) related to severity pancreatitis unclear.To evaluate effect TG on hypertriglyceridemic (HTGP).Retrospective cohort study.We reviewed records 144 patients with HTGP from 1999 2013 at Tri-Service General Hospital. Patients possible etiology such as gallstones, those consuming alcohol or drugs, infections were excluded. The classification was based revised Atlanta classification. We...
Aims: Obstructive sleep apnea (OSA) and insomnia commonly coexist; hypnotics are broadly prescribed for therapy. However, the safety of use in OSA patients is unclear. We conducted a retrospective case-control study to investigate risk adverse respiratory events hypnotics-using patients. Methods: obtained data from Taiwan National Health Insurance Database 1996 2013. The case group included 216 with newly diagnosed events, including pneumonia acute failure. control without which was randomly...
Carbapenem-resistant Acinetobacter baumannii (CRAB) is a key pathogen associated with ventilator-associated pneumonia (VAP). Research on treatment outcomes, especially ventilator dependence, in patients VAP caused by CRAB remains limited.This retrospective multicenter study included ICU-admitted CRAB. The original cohort was as the mortality evaluation cohort. dependence cases that survived more than 21 days after and without prolonged ventilation before onset. rate, clinical factors outcome...
Tobacco smoking has been found associated with lower cardiorespiratory fitness in white and black males; however, few studies have not conducted to clarify such relationship Asian males. We performed a cross-sectional study investigate the association between tobacco status physical 3,669 military males, averaged 29.4 years of age, from hospitalization events armed forces (CHIEF) Taiwan during 2014. There were 1,376 current smokers, others noncurrent smokers. The effective sample size...
Tuberculosis (TB) and sarcoidosis are both granulomatous diseases with potential interassociations. However, much uncertainty remains; thus, the present study aimed to clarify association between these diseases.We established two cohorts in this retrospective longitudinal cohort using data obtained from Taiwan National Health Insurance Database 2000 2015. One cohort, which comprised 31 221 patients TB 62 442 age-, sex- index year-matched controls, was used analyse risk of sarcoidosis; other...
Abstract Nosocomial pneumonia caused by carbapenem-resistant gram-negative bacteria (CRGNB) is a growing threat due to the limited therapeutic choices and high mortality rate. The aim of this study was evaluate prognostic factors for in patients with nosocomial CRGNB impact colistin-based therapy on outcomes intensive care unit (ICU) patients. We conducted retrospective ICUs five tertiary teaching hospitals Taiwan. Patients from January 2016 December were included. Prognostic analyzed using...
Tigecycline has in vitro bacteriostatic activity against a broad spectrum of bacteria, including carbapenem-resistant Gram-negative bacteria (CR-GNB). However, the role tigecycline treatment nosocomial pneumonia caused by CR-GNB remains controversial and clinical evidences are limited. We aimed to investigate benefits as part combination intensive care unit (ICU).This multi-centre cohort study retrospectively enrolled ICU-admitted patients with CR-GNB. Patients were categorized based on...
The purpose of the study was to investigate liability heritability incidence angel wing (LHIAW) on growth and egg production performance. A total 1,696 geese including 990 offspring from heavy body weight line (selecting for 6 generations) 775 high 3 generations), 69 birds their parent group two lines were observed (IAW). In White Roman geese, (IAW) 54.6%. Among 294 progenies families, IAW 65.6%. estimated this 0.39. 42.3%. 124 43.5%. 0.03. both-side type significantly heavier than those...
Abstract Hospital-acquired pneumonia (HAP) and ventilator-associated (VAP) caused by carbapenem-resistant Acinetobacter baumannii (CRAB) are both associated with significant morbidity mortality in daily clinical practice, as well a critical care setting. It is unclear whether colistin susceptible-only (CSO AB) unique phenotype separate from or subset of CRAB-associated pneumonia. The aim this study to investigate the prevalence CSO AB compare presentation outcome between critically ill...
According to several studies, tuberculosis (TB) may be involved in the pathogenesis of cardiovascular disease. However, relationship between TB and peripheral arterial disease (PAD) has not been studied. The aim this study was investigate whether patients with exhibit an increased risk developing PAD.The data assessed national population-based cohort were obtained from Taiwan National Health Insurance Database 2000 2010. Patients newly diagnosed selected using International Classification...
Abstract The metabolically healthy obese (MHO) characterized by the absence of metabolic syndrome have shown superior cardiorespiratory fitness (CRF) and similar muscular strength as compared with unhealthy (MUO). However, this finding might be biased baseline sedentary behavior in general population. This study utilized 3669 physically active military males aged 18–50 years Taiwan. Obesity were respectively defined body mass index ≥ 27.5 kg/m 2 presence at least two major components...
Abstract Background The importance or necessity of a loading dose when prescribing intravenous colistin has not been well established in clinical practice, and approximate one-third to half patients with carbapenem-resistant gram-negative bacteria (CRGNB) infection did receive the administration dose. aim this study is investigate efficacy risk acute kidney injury for critically ill nosocomial pneumonia caused by CRGNB. Methods This was multicenter, retrospective that recruited ICU-admitted...
Some antituberculosis agents may cause hypothyroidism, and thyroid hormones play a vital role in Mycobacterium tuberculosis infection. However, the relationship between (TB) hypothyroidism has not been clearly established. Therefore, this retrospective, longitudinal cohort study aimed to investigate association these two diseases using 2000-2017 data from Taiwan's National Health Insurance Research Database. The TB cohorts were matched with control group 1:4 ratio. Adjusted hazard ratios...
COVID-19, caused by SARS-CoV-2, has rapidly spread to more than 160 countries worldwide since 2020. Despite tremendous efforts and resources spent trying explore antiviral drugs, there is still no effective clinical treatment for COVID-19 date. Approximately 15% of cases progress pneumonia, patients with severe pneumonia may die from acute respiratory distress syndrome (ARDS). It believed that pulmonary fibrosis SARS-CoV-2 infection further leads ARDS, often resulting in irreversible...
Background: Evaluating the options for antibiotic treatment carbapenem-resistant Gram-negative bacteria (CR-GNB)-associated pneumonia remains crucial. We compared therapeutic efficacy and nephrotoxicity of two combination therapies, namely, colistin + carbapenem (CC) versus tigecycline (CT), treating CR-GNB-related nosocomial in critically ill patients. Methods: In this multicenter, retrospective, cohort study, we recruited patients admitted to intensive care units diagnosed with...
Life-threatening refractory metabolic acidosis due to starvation ketoacidosis is rarely reported, even among nondiabetic pregnant women, and may be overlooked. Furthermore, stressful situations increase the severity. In present case, a multiparous woman was admitted for near-fatal asthma attack vomiting during third trimester of pregnancy. She intubated rapidly developed high anion gap acidosis. We diagnosed patient with based on concomitant periods stress pregnancy absence other causes...
Methotrexate has immunosuppressive effects and is administered for refractory chronic urticaria. We present a case of Pneumocystis jirovecii pneumonia in patient with urticaria managed by low-dose weekly methotrexate treatment (total cumulative dose 195mg). Our study highlights the importance providing prompt diagnosis patients under therapy.
Background: Sjögren's syndrome (SS) is a chronic autoimmune disease with lymphocytic exocrine gland infiltration causing dry mouth and eyes. The can develop alone (primary SS, PSS) or other diseases (secondary SSS). PSS has been suggested to increase the acute pancreatitis risk. However, whether all patients SS share this higher risk remains uncertain. This nationwide population-based cohort study aimed detect associations between pancreatitis. Methods: We identified 11,922 individuals...