J. Fernández

ORCID: 0000-0002-5297-4611
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About
Contact & Profiles
Research Areas
  • Radiation Dose and Imaging
  • Advanced X-ray and CT Imaging
  • Digital Radiography and Breast Imaging
  • Advanced Radiotherapy Techniques
  • Astrophysics and Cosmic Phenomena
  • Radiology practices and education
  • Dark Matter and Cosmic Phenomena
  • Radiation Detection and Scintillator Technologies
  • Medical Imaging Techniques and Applications
  • Radioactivity and Radon Measurements
  • Cardiac, Anesthesia and Surgical Outcomes
  • Neutrino Physics Research
  • Radio Astronomy Observations and Technology
  • Particle Detector Development and Performance
  • Astronomy and Astrophysical Research
  • Cardiac Imaging and Diagnostics
  • Solar and Space Plasma Dynamics
  • Particle Accelerators and Free-Electron Lasers
  • Gamma-ray bursts and supernovae
  • Ocular and Laser Science Research
  • Astronomical Observations and Instrumentation
  • Effects of Radiation Exposure
  • Geophysics and Gravity Measurements
  • Radiation Effects and Dosimetry
  • Stellar, planetary, and galactic studies

Hospital Clínico San Carlos
2013-2024

Instituto de Investigación Sanitaria del Hospital Clínico San Carlos
2014-2024

Universidad Complutense de Madrid
2010-2024

Universitat de València
2024

Vall d'Hebron Hospital Universitari
2022

Vall d'Hebron Institute of Oncology
2022

Hospital Universitario Virgen de la Arrixaca
2020

Laboratoire de Biologie Physico-Chimique des Protéines Membranaires
2016

Hospital de Basurto
1993-2015

Max Planck Innovation
1996-1999

Abstract Anti-BRAF/EGFR therapy was recently approved for the treatment of metastatic BRAF V600E colorectal cancer (mCRC BRAF-V600E ). However, a large fraction patients do not respond, underscoring need to identify molecular determinants response. Using whole-exome sequencing in discovery cohort with mCRC treated anti-BRAF/EGFR therapy, we found that inactivating mutations RNF43 , negative regulator WNT, predict improved response rates and survival outcomes microsatellite-stable (MSS)...

10.1038/s41591-022-01976-z article EN cc-by Nature Medicine 2022-09-12

The aim of this work has been to determine typical occupational dose levels in interventional radiology and cardiology installations relate doses patient dosimetry through the dose-area product. An experimental correlation between environmental dosimetric records products centres studied was established. study covered a sample 83 procedures performed by 10 specialists six laboratories. radiologists cardiologists monitored wore nine thermoluminescent chips next eyes, forehead, neck, hands,...

10.1259/bjr.71.849.10195011 article EN British Journal of Radiology 1998-09-01

To report estimated radiation doses to the eye lens of interventionalist from procedures performed with and without use protection measures.Scattered for seven interventional radiology fluoroscopic systems were measured by using phantoms simulating patients 16-28 cm in thickness undergoing low-, medium-, high-mode fluoroscopy, cine cardiac imaging, digital subtraction angiography (DSA). The low- high-dose scenarios estimated. Beam angulation, biplanar equipment, working distance, procedure...

10.1148/radiol.2482071800 article EN Radiology 2008-07-16

This report describes occupational radiation doses of interventional cardiologists over 15 years and assesses action undertaken to optimize protection. Personal dosimetry records nine staff eight cardiology fellows were recorded using personal dosemeters worn under their lead aprons. The hospital in which this study was conducted currently performs 5000 procedures per year. has improved its facilities since 1989, when it had two old-fashioned theatres, include four rooms with more advanced...

10.1259/bjr/26829723 article EN British Journal of Radiology 2006-04-21

Abstract Large exposures incurred in interventional radiology procedures make it advisable to establish reference dose values. These values should be quoted quantities representative of the radiological risk patient. In Spain, measurement methods were developed comply with European Directive on Patient Protection. Dose-area product and, when feasible, surface using thermoluminescent dosimetry chips measured. Both approaches are discussed, as well their potential use patient protection...

10.1259/0007-1285-68-815-1215 article EN British Journal of Radiology 1995-11-01

Coronary angiography and percutaneous transluminal coronary angioplasty procedures performed in four different facilities were monitored the present study by measuring maximum skin dose, dose-area product other operational parameters. Radiographic slow film, thermoluminescent dosemeters transmission ion chambers used to measure dose related quantities. Values of 107-711 mGy for 27.3-370.6 Gy cm2 found, together with cumulative estimates 110-3706 mGy. A discussion relationship measured values...

10.1259/bjr.74.877.740048 article EN British Journal of Radiology 2001-01-01

Context. The ESO public survey VISTA Variables in the Vía Láctea (VVV) surveyed inner Galactic bulge and adjacent southern disk from 2009–2015. Upon its conclusion, complementary VVV extended (VVVX) has expanded both temporal as well spatial coverage of original area, widening it 562 to 1700 sq. deg., providing additional epochs JHK s filters 2016–2023. Aims. With completion VVVX observations during first semester 2023, we present here observing strategy, a description data quality access,...

10.1051/0004-6361/202450584 article EN cc-by Astronomy and Astrophysics 2024-07-01

Patient and staff dose values in an interventional cardiology laboratory for different operational modes several patient thicknesses (from 16 to 28 cm, simulated using polymethylmethacrylate) are presented. When increasing depending on fluoroscopy cine modes, occupational doses can increase >30 times the baseline level. Scatter rates at cardiologist's position with no radiation protective tools ranged from 1 14 mSv h−1 fluoroscopy, 10 47 during acquisition. entrance surface air kerma...

10.1093/rpd/nci369 article EN Radiation Protection Dosimetry 2006-01-26

BARNHART, JAMES PHD; LEVENE, HAROLD VILLAPANDO, ELAINE BS; MANIQUIS, JACK FERNANDEZ, JOSÉ RICE, SALLIE JABLONSKI, ED GJØEN, TOR TOLLESHAUG, HELGE PHD Author Information

10.1097/00004424-199009001-00070 article EN Investigative Radiology 1990-09-01

In the present investigation, we analyze dose of 5034 patients (20 137 images) who underwent mammographic examinations with a full‐field digital mammography system. Also, evaluate system calibration by analyzing exposure factors as function breast thickness. The information relevant to this study has been extracted from image DICOM header and stored in database during 3‐year period (March 2001–October 2003). Patient data included age, thickness, kVp, mAs, target/filter combination, nominal...

10.1118/1.1784591 article EN Medical Physics 2004-08-19

To retrospectively evaluate patient radiation doses in projection radiography after the transition to computed (CR) authors' hospital.The hospital's ethical committee approved study and waived informed consent. In 2001, a dose reduction initiative was implemented, which involved collecting radiographic parameters, calculating entrance doses, monitoring changes with an online computer, training program for radiographers conducted. A database 204 660 values used compute over time. Sample sizes...

10.1148/radiol.2432050930 article EN Radiology 2007-03-14

<h3>BACKGROUND AND PURPOSE:</h3> Radiation exposure from neurointerventional procedures can be substantial, with risk of radiation injuries. We present the results a follow-up program applied to potential skin injuries in interventional neuroradiology based on North American and European guidelines. <h3>MATERIALS METHODS:</h3> The following guidelines approved 2009 by SIR CIRSE have been used over last 2 years identify patients requiring clinical follow-up: peak dose &gt;3 Gy, air kerma at...

10.3174/ajnr.a3211 article EN cc-by American Journal of Neuroradiology 2012-08-02

Journal Article Influence of dosemeter position for the assessment eye lens dose during interventional cardiology Get access Sara Principi, Principi 1Institut de Tècniques Energètiques, Universitat Politècnica Catalunya (UPC), Barcelona 08028, Spain Search other works by this author on: Oxford Academic PubMed Google Scholar Mercè Ginjaume, Ginjaume * *Corresponding author: merce.ginjaume@upc.edu Maria Amor Duch, Duch Roberto M. Sánchez, Sánchez 2Medical Physics, Hospital Clínico San Carlos,...

10.1093/rpd/ncu359 article EN Radiation Protection Dosimetry 2014-12-15

Journal Article Measurements of eye lens doses in interventional cardiology using OSL and electronic dosemeters Get access R. M. Sanchez, Sanchez * 1Medical Physics, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Madrid, Spain *Corresponding author: robertomariano.sanchez@salud.madrid.org Search for other works by this author on: Oxford Academic PubMed Google Scholar E. Vano, Vano Spain2Radiology Department, Faculty Medicine, Universidad Complutense J. Fernandez,...

10.1093/rpd/nct368 article EN Radiation Protection Dosimetry 2014-01-23

In 2011, the International Commission on Radiologic Protection established an absorbed-dose threshold to brain of 0.5 Gy as likely produce cerebrovascular disease. this paper, authors investigated doses delivered patients during clinical neuroradiology procedures in a university hospital.The radiation dose was 99 diagnostic and therapeutic interventional procedures. Brain were calculated mathematic model adult standard anthropomorphic phantom by using technical data x-ray biplane system...

10.3174/ajnr.a3884 article EN cc-by American Journal of Neuroradiology 2014-03-13

The purpose of this work is to evaluate radiation doses the lens urologists during interventional procedures and compare them with values measured radiology, cardiology vascular surgery. measurements were carried out in a surgical theatre using mobile C-arm system electronic occupational dosimeters (worn over lead apron). Patient staff dose collected sample 34 urology interventions (nephrolithotomies). same dosimetry was used other medical specialties for comparison purposes. Median 3rd...

10.1088/0952-4746/36/1/37 article EN Journal of Radiological Protection 2015-11-19

Objectives: Radiation dose management systems (DMS) are currently used to help improve radiation protection in medical imaging and interventions. This study presents our experience using a homemade DMS called DOLQA (Dose On-Line for Quality Assurance). Methods: Our is connected 14 X-ray university hospital linked the central data repository of large network 16 public hospitals Autonomous Community Madrid, with 6.7 million inhabitants. The system allows us manage individual patient groups...

10.1259/bjr.20211340 article EN cc-by-nc British Journal of Radiology 2022-01-10
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