A5011087733- SARS-CoV-2 and COVID-19 Research
- Vaccine Coverage and Hesitancy
- Glioma Diagnosis and Treatment
- COVID-19 epidemiological studies
- Microtubule and mitosis dynamics
- Viral gastroenteritis research and epidemiology
- Cerebrospinal fluid and hydrocephalus
- Reproductive Health and Technologies
- COVID-19 and Mental Health
- Neurogenesis and neuroplasticity mechanisms
- Immune cells in cancer
- COVID-19 Pandemic Impacts
- Photosynthetic Processes and Mechanisms
- Assisted Reproductive Technology and Twin Pregnancy
- COVID-19 Clinical Research Studies
- Pharmaceutical studies and practices
- Adipokines, Inflammation, and Metabolic Diseases
- Peripheral Neuropathies and Disorders
- Influenza Virus Research Studies
- Signaling Pathways in Disease
- Prenatal Screening and Diagnostics
- Urticaria and Related Conditions
- Digestive system and related health
- Mechanisms of cancer metastasis
- Protein Degradation and Inhibitors
University of Liège
2018-2025
Centro de Infertilidad y Reproducción Humana
2007
We herein present the initial experiences of CEFER Institute Reproduction in formation a new family model: two biological mothers, lesbians, one who provides eggs and other carries embryo her womb. have called this model ROPA (Reception Oocytes from PArtner). It is pioneer event Spain among first at worldwide level.Fourteen lesbian couples undergone treatment using technique. This paper briefly describes Six pregnancies been obtained 13 transfers. There were miscarriages there are three...
Abstract Short survival of glioblastoma (GBM) patients is due to systematic tumor recurrence. Our laboratory identified a GBM cell subpopulation able leave the mass (TM) and invade subventricular zone (SVZ-GBM cells). SVZ-GBM cells escape treatment appear contribute This study aims identify proteins specifically expressed by define their role(s) in aggressiveness The proteome was compared between located initial TM using spectrometry. Among differentially proteins, we confirmed B7-H3 western...
New COVID-19 strains and waning vaccine effectiveness prompted initiatives for booster vaccination. In Belgium, healthcare providers (HCPs) received a second in July 2022, with eligible individuals receiving third autumn. Primary HCPs (PHCPs) play crucial role organization patient communication. This study, conducted February–March 2023, surveyed 1900 Belgian PHCPs to assess their views on periodic boosters themselves patients. The survey included questions sociodemographic information,...
In Belgium, nursing home staff (NHS) and residents were prioritised for COVID-19 vaccination. However, vaccine hesitancy may have impacted vaccination rates. this study, a random stratified sample of NHS (N = 1142), vaccinated unvaccinated, completed an online questionnaire on (between 31 July 15 November 2021). who hesitated or refused the asked main reason their hesitation/refusal. Those hesitated, but eventually accepted vaccination, why they changed minds. Overall, 29.5% all respondents...
Primary glioblastoma is the most frequent human brain tumor in adults and generally fatal due to recurrence. We previously demonstrated that glioblastoma-initiating cells invade subventricular zones promote their radio-resistance response local release of CXCL12 chemokine. In this work, we show mitotic Aurora A kinase (AurA) activated through CXCL12-CXCR4 pathway an ERK1/2-dependent manner. Moreover, CXCL12-ERK1/2 signaling induces expression Ajuba, main cofactor AurA, which allows...
Abstract Gliomas aberrantly express programmed cell death ligand-1 (PD-L1), which has a pivotal role in immunoevasion. The splicing isoform of FKBP5 , termed FKBP51s, is PD-L1 foldase, assisting the immune checkpoint molecule maturation and expression on plasma membrane. concept that supports tumor-intrinsic properties increasingly emerging. aim present work was to confirm pro-tumoral effect human glioma survival, stemness capacity resistance, address issue whether, by targeting its foldase...
A 9-year-old, spayed female, Airedale Terrier was euthanatized and necropsied after a progressive clinical course that included Horner's syndrome of the left eye unilateral atrophy masticatory muscles. Although gross lesions were limited, polyradiculoneuritis ganglionitis most severe in trigeminal nerves ganglia confirmed histologically. The inflammatory infiltrate consisted predominantly macrophages B T lymphocytes phenotypically by immunostaining. result damage to postganglionic...
In the SCOPE study, we monitored SARS-CoV-2 antibodies in a national sample of residents and staff from Belgian nursing homes. Here, report seroprevalence among infected infection-naive after primary COVID-19 vaccination campaign. Among 1554 vaccinated home 1082 69 homes Belgium, assessed proportion having approximately two (April 2021), four (June six months (August 2021) two-dose regimen BNT162b2 vaccine. We measured using antibody rapid tests collected socio-demographic medical data an...
In Belgium, nursing home (NH) staff (NHS) and residents were prioritised for the initial COVID-19 vaccination successive booster doses. The campaign first started in September 2021 Belgian NH. Our study about vaccine hesitancy towards NHS already showed a degree of fear primary course (T1). This new aims to evaluate get (T2) population fully vaccinated (with two doses) NHS. A random stratified sample who received (N = 954) completed an online questionnaire on (between 25/11/2021 22/01/2022)....
Nursing home residents (NHR) and staff have been disproportionally affected by the COVID-19 pandemic were therefore prioritised in vaccination strategy. However, frail older adults, like NHR, are known to decreased antibody responses upon targeting other viral antigens.As real-world data on vaccine responsiveness, we assessed prevalence of SARS-CoV-2 antibodies among Belgian NHR during primary campaign.In total, tested 1629 1356 across 69 NHs for presence IgM/IgG using rapid tests. We...
Glioblastoma (GBM) is the most frequent and aggressive primary tumor in central nervous system. Previously, secretion of CXCL12 brain subventricular zones has been shown to attract GBM cells protect against irradiation. However, exact molecular mechanism behind this radioprotection still unknown. Here, we demonstrate that modulates phosphorylation MAP kinases their regulator, nuclear kinase phosphatase 1 (MKP1). We further show MKP1 able decrease cell death promote DNA repair after...
<title>Abstract</title> Background COVID-19 vaccine effectiveness declines months after vaccination. Therefore, it is likely that during the next few years, people may be repeatedly offered a booster to enhance humoral immunity levels. A growing number of are questioning whether benefits outweigh side-effects. Objective This study aims (1) identify most frequently reported side-effects different doses mRNA vaccines, (2) and longest lasting symptoms; (3) predict likelihood having...
When COVID-19 vaccines were implemented, nursing home residents (NHRs) and staff (NHS) in Belgium prioritized for vaccination. To characterize the vaccine response over time this population to identify poorly responding groups, we assessed antibody concentrations two (T1), four (T2) six months (T3) after primary course BNT162b2 vaccination groups of infection-naive/infection-primed NHRs/NHS, with/without comorbidity (NHRs only). Participant (N = 125 per group) defined within a national...
COVID-19 vaccine effectiveness declines months after vaccination. Therefore, it is likely that during the next few years, people may be repeatedly offered a booster to enhance humoral immunity levels. A growing number of are questioning whether benefits outweigh side-effects.
Abstract Background The ARON study, a randomized controlled trial, assesses behavioural intervention incorporating clinically guided C-reactive protein (CRP) point-of-care testing and parental information booklet to reduce inappropriate antibiotic prescriptions for acutely ill children in Belgian primary care. Objectives To explore GP parent views experiences regarding the trial intervention. Methods We conducted qualitative embedded process evaluation general practice. Semi-structured...
counterparts as well excellent clinical outcome.Clinical results obtained in the present study indicate possible use of Cryotop method for egg donation programs, and also high potential establishing oocyte banking, which could be helpful many patients with different indications.
3.73%, respectively.Diploidy rates were also significantly increased in three patients from the infertile group.Overall, 12 out of 24 (50%) had a significant increase sperm aneuploidy with 7 presenting an rate XY gametes and 8 21 disomies. Conclusion:Our study shows that ICSI severe oligospermia have higher chromosomally abnormal gametes.These abnormalities use could be transmitted to offspring, elevated risks Klinefelter trisomy suggesting genetic counselling should offered all entering...