Kartik Mandal

ORCID: 0000-0002-5319-1918
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About
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Research Areas
  • Ubiquitin and proteasome pathways
  • Multicomponent Synthesis of Heterocycles
  • Natural product bioactivities and synthesis
  • Protein Degradation and Inhibitors
  • Synthesis and bioactivity of alkaloids
  • Cancer therapeutics and mechanisms
  • Plant biochemistry and biosynthesis
  • Genomics and Chromatin Dynamics
  • Microbial Natural Products and Biosynthesis

National Centre for Cell Science
2024-2025

Savitribai Phule Pune University
2024

Abstract Cycloartenone and cycloartenol, two plant‐derived triterpenoids possessing cyclopropane ring were isolated from the latex of Artocarpus heterophyllus (jackfruit). Cycloartenol was chemically modified to synthesize dihydrocycloartenol via acetylation deacetylation methodology followed by hydrogenation. Hydroxyl group present in cycloartenol also employed for nitro benzoate formation. All synthesized compounds assayed against MCF7 breast cancer cell line their anticancer properties.

10.1002/slct.202403698 article EN ChemistrySelect 2025-03-01
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