A5102706710- Topic Modeling
- Health and Well-being Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Genetics and Plant Breeding
- Genetic and phenotypic traits in livestock
- Genetic Mapping and Diversity in Plants and Animals
- Cardiovascular Function and Risk Factors
- Natural Language Processing Techniques
- Neurosurgical Procedures and Complications
- Perfectionism, Procrastination, Anxiety Studies
- Rural development and sustainability
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Orthopaedic implants and arthroplasty
- Chronic Lymphocytic Leukemia Research
- Agroforestry and silvopastoral systems
- Bioinformatics and Genomic Networks
- Workplace Health and Well-being
- Gestational Diabetes Research and Management
- Interpreting and Communication in Healthcare
- Regulation of Appetite and Obesity
- Syphilis Diagnosis and Treatment
- CNS Lymphoma Diagnosis and Treatment
- Genetic Associations and Epidemiology
- Circadian rhythm and melatonin
- Dermatology and Skin Diseases
First Hospital of Shijiazhuang
2023-2025
Tianjin Medical University
2023-2025
Hebei Medical University
2023-2025
Third Hospital of Hebei Medical University
2025
Zhejiang Center for Disease Control and Prevention
2024
Shanxi Medical University
2019-2024
Shanxi Academy of Medical Sciences
2023-2024
Sichuan University
2024
West China Hospital of Sichuan University
2024
Taiyuan Central Hospital
2024
The hypothalamus plays a crucial role in the progression of obesity and diabetes; however, its structural complexity cellular heterogeneity impede targeted treatments. Here, we profiled single-cell spatial transcriptome obese sporadic type 2 diabetic macaques, revealing primate-specific distributions clusters genes as well region, cell-type-, gene-feature-specific changes. infundibular (INF) paraventricular nuclei (PVN) are most susceptible to metabolic disruption, with PVN being more...
Several observational studies have investigated the association of insomnia with psychiatric disorders. Such yielded mixed results, and whether these associations are causal remains unclear. Thus, we aimed to identify relationships between five major disorders.The analysis was implemented six genome-wide studies; one for disorders (attention-deficit/hyperactivity disorder, autism spectrum depressive schizophrenia, bipolar disorder). A heterogeneity in dependent instrument (HEIDI) approach...
OBJECTIVE To identify predictors of body weight (BW) reduction ≥15% with tirzepatide treatment and to describe associated clinical parameters participants type 2 diabetes (T2D) who achieved different categorical measures BW (<5%, ≥5 <10%, ≥10 <15%, ≥15%) across four studies from the phase 3 SURPASS trial program for T2D. RESEARCH DESIGN AND METHODS The multivariate model predictor a included age, sex, race, BW, HbA1c, dose baseline metformin use, fasting serum glucose,...
This study aims to evaluate the clinical significance of ultrasound-based measurement optic nerve sheath diameter (ONSD) in predicting intracerebral hemorrhage (ICH) complicated by cerebral-cardiac syndrome (CCS). Patients with ICH and who were treated intensive care unit (ICU) at Shijiazhuang People's Hospital between October 2021 November 2022 included this study. Participants divided into two groups: those CCS without. Various parameters, including sex, age, electrocardiogram (ECG)...
Sarcopenia had been identified as a factor influencing the postoperative outcomes of lumbar surgery. The effect sarcopenia on surgical in patients who underwent oblique lateral interbody fusion (OLIF) not yet examined. aim our study was to investigate association between and low back pain (LBP) following OLIF provide recommendations for strategy. 116 were retrospectively reviewed. Patients classified into group (Group SP) non-sarcopenia NSP). According whether instruments performed, Group SP...
<title>Abstract</title> <bold>Background:</bold> Type 2 diabetes mellitus (T2DM) risk gene play a crucial role in determining birth weight. We aimed to test the association between cyclin-dependent kinase 5 regulatory subunit-associated protein 1-like 1 (<italic>CDKAL1)</italic>gene and low weight (LBW). <bold>Methods:</bold> A comprehensive literature search was conducted across major databases up September 20, 2024. Original articles evaluating <italic>CDKAL1 </italic>gene birthweight were...
Background: Periconception folic acid supplementation has been suggested to protect against congenital heart disease (CHD), but the association between maternal red blood cell (RBC) folate, gold-standard biomarker of folate exposure, and subsequent offspring CHD risk is lacking. Objective: To quantify periconception RBC risk. Design: Prospective, nested, case–control study 1-sample Mendelian randomization. (ClinicalTrials.gov: NCT02737644) Setting: 29 maternity institutions in 12 districts...
This study examines the association of sleep quality with job burnout among Chinese coal mine staff. 3832 subjects were selected from a group located in Shanxi Province China. Job was evaluated by Maslach Burnout Inventory-General Survey and acquired self-reported questionnaire. We used inverse probability treatment weighting propensity score to mimic randomization minimize bias estimations. Sensitivity analysis conducted test robustness our findings. identified that good significantly...
Restless legs syndrome is a movement disorder that seriously affects the quality of life patients. It characterized by marked discomfort mainly occurring in deep tissues lower extremities, including muscle or bone chafing, as well crawling sensations pulling sensations. These often cause patients to awaken after falling asleep and feel urge walk around, which their sleep quality. Patients with restless leg exhibit significantly enhanced sympathetic nerve activity immune disorders, while...
Abstract Dyslipidemia is highly prevalent and an important modifiable risk factor of cardiovascular disease in China. However, there little information on the dyslipidemia Shangcheng district, eastern Therefore, this study aims to investigate prevalence associated factors among community adults area. A based cross-sectional was conducted from August 1 November 30, 2020. The utilized a multi-stage probability sampling method enroll permanent residents (those who have resided region for 6...
Large language models (LLMs) have achieved remarkable progress in many natural processing tasks. However, our experiment reveals that, stance detection tasks, LLMs may generate biased stances due to spurious sentiment-stance correlation and preference towards certain individuals topics, thus harming their performance. Therefore, this paper, we propose Mitigate Biases of with Calibration (MB-Cal). In which, a novel gated calibration network is devised mitigate the biases on reasoning results...
Background Hot flashes are common symptoms afflicting perimenopausal women. A stellate ganglion block (SGB) is believed to be an effective treatment for hot flashes; however, more evidence needed evaluate its safety and efficacy in relieving flashes. Objective To investigate the of SGB Methods randomized controlled trial was conducted at Shanxi Bethune Hospital. Forty women with were recruited from April 2022 November randomly assigned receive either 6 consecutive treatments or saline...
Judges may experience mental health problems, which reduces their performance in juridical cases, and constitutes a great threat to both the authority of law social justice. This study aimed assess prevalence psychological distress among judges examine effect perfectionism on with age gender as moderators.This survey was carried out person 565 Chinese 2016, using Almost Perfect Scale-Revised Kessler Psychological Distress Scale. The effects explored by Structural Equation Model (SEM),...
Lung cancer is one of the most common cancers in China and has a high mortality rate. Most patients who are diagnosed have lost opportunity to undergo surgery. Aberrant metabolism closely associated with tumorigenesis. We aimed identify an effective metabolism-related prediction model for assessing prognosis based on genome atlas (TCGA) GSE116959 databases.TCGA datasets from Gene Expression Omnibus were used obtain lung adenocarcinoma (LUAD) data. Additionally, we captured genes (MRGs)...
Hemodialysis (HD) patients represent a high-risk group for hepatitis B infection. It is crucial to administer vaccination and stimulate higher more sustained levels of anti-HBs. Our aim enhance the immunogenicity persistence by implementing high-dose prolonged vaccine schedule regimen in HD patients.
Continual Language Learning (CLL) in multilingual translation is inevitable when new languages are required to be translated. Due the lack of unified and generalized benchmarks, evaluation existing methods greatly influenced by experimental design which usually has a big gap from industrial demands. In this work, we propose first Evaluation benchmark CLLE translation. consists Chinese-centric corpus — CN-25 two CLL tasks close-distance language continual learning task family designed for...
Abstract Background Oxidative stress leads to adverse atrial remodeling in diabetes mellitus. AMP-activated protein kinase (AMPK) agonists have been shown prevent cardiomyocytes from oxidative by improving mitochondrial function, but their underlying mechanisms are not completely understood. This study investigated the molecular changes and regulatory AMPK agonists, metformin AICA ribonucleotide (AICAR). Methods Mouse (HL-1 cells) rats with type 2 mellitus (DM) were used as models. A total...
To investigate the clinical characteristics of diffuse large B-cell lymphoma(DLBCL) patients with bone marrow involvement and chromosome abnormalities, further analyze correlation between degree abnormality prognosis.The data 88 diagnosed DLBCL complete chromosomal findings in Shanxi Province Cancer Hospital were retrospectively analyzed. The χ2 test was used to their characteristics, Kaplan-Meier method PFS OS, log-rank comparison.Chromosome abnormalities detected 31 patients(35.2%), 15...
Pervasive ferrihydrite (Fh)- humic acid (HA) coprecipitates plays significant role in the fate of heavy metals subsurface environment. However, quantitative investigation adsorption and reduction processes Cr(VI) by Fh-HA corresponding multi-step reaction mechanism remain unclear. In this study, kinetic were characterized using experimental simulation methods, which quantified antagonistic synergistic effects. Results showed that rate was 7–60 times higher than reduction, attributed to Fh...