A5079548959- Ophthalmology and Eye Disorders
- Glaucoma and retinal disorders
- Vestibular and auditory disorders
- Ophthalmology and Visual Impairment Studies
- Pituitary Gland Disorders and Treatments
- Cerebral Venous Sinus Thrombosis
- Hepatocellular Carcinoma Treatment and Prognosis
- Photonic Crystals and Applications
- Ocular Disorders and Treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Retinal Development and Disorders
- Retinal Diseases and Treatments
- Cerebrovascular and Carotid Artery Diseases
- Advanced Antenna and Metasurface Technologies
- Ocular Oncology and Treatments
- Metamaterials and Metasurfaces Applications
- Congenital Diaphragmatic Hernia Studies
- Intraocular Surgery and Lenses
- Angiogenesis and VEGF in Cancer
- Facial Trauma and Fracture Management
- Head and Neck Surgical Oncology
- Cerebrospinal fluid and hydrocephalus
- Uterine Myomas and Treatments
- Cerebral Palsy and Movement Disorders
- Meningioma and schwannoma management
Sun Yat-sen University
2014-2025
Jiangsu University
2008-2025
Xuzhou Medical College
2025
Creative Commons
2023
May Institute
2015
National Natural Science Foundation of China
2015
Leber congenital amaurosis (LCA) is a genetically heterogeneous disease with, to date, 19 identified causative genes. Our aim was evaluate the mutations in all genes Chinese families with LCA.LCA patients from 41 unrelated were enrolled, including 25 previously unanalyzed and 16 screened by Sanger sequencing, but no mutations. Genetic variations whole-exome sequencing then validated using sequencing.A total of variants predicted affect protein coding or splicing detected 40 confirmed...
Acute acquired concomitant esotropia (AACE) is a rare, distinct subtype of esotropia. The purpose this retrospective study was to describe the clinical characteristics and discuss classification etiology AACE. Charts from 47 patients with AACE referred our institute between October 2010 November 2014 were reviewed. All participants underwent complete medical history, ophthalmologic orthoptic examinations, brain orbital imaging. Mean age at onset 26.6 ± 12.2 years. Of 18 cases deviations ≤ 20...
The clinical characteristics and surgical outcomes in a large sample of patients with intermittent exotropia (IXT) as well an analysis risk factors associated failures are presented this article. Data from IXT who received management at the Eye Hospital, Zhongshan Ophthalmic Center, Sun Yat-Sen University, China January 2009 to December 2013 were reviewed retrospectively. Included within data pre- postoperative ocular motility, primary alignment, binocular vision.A total 1228 reviewed. Males...
AIM: To investigate the underlying factors by establishing a new paradigm for assessing control ability under stereopsis testing conditions. METHODS: This was prospective observational study. We evaluated of intermittent exotropia (IXT) patients in three conditions: natural 2D optotype viewing, viewing with polarized glasses, and 3D glasses. Recording smartphone, we captured videos to analyze accurate time spontaneous exodeviation subsequent realignment before after breaking fusion....
To investigate the characteristics of horizontal rectus muscle insertion sites in patients with infantile esotropia (IE) and acute acquired concomitant (AACE). The medical records 166 IE 261 AACE who underwent surgeries were reviewed retrospectively, including age at surgery, spherical equivalent (SE), angle esodeviation near distance. limbus-insertion distances (LID) widths medial (MR) lateral (LR) muscles measured intraoperatively using a caliper. parameters clinical features compared...
Purpose To evaluate the effectiveness and safety of botulinum toxin type A (BTXA) injection with reduced volume without electromyographic guidance for treatment acute acquired comitant esotropia (AACE) 25 prism diopters (PD) or less. Methods The authors reviewed medical records 60 patients AACE PD less, including 40 treated BTXA injections (BTXA group) 20 Fresnel (Fresnel group). Patients in group were injected 5 to 6.25 U 0.04 mL saline into bilateral medial rectus muscles absence...
Uterine fibroids are common benign tumors of the female reproductive system, primarily affecting women childbearing age. These worsen patients' quality life and fertility. Current treatment options for symptomatic uterine include drug therapy, surgical intervention, interventional procedures. Among these, artery embolization (UAE) has emerged as an effective treatment. Recently, transradial approach (TRA) distal (dTRA) have gained attention alternative access routes UAE. This study aims to...
Retinoblastoma is a curable intraocular malignancy in children. However, clinical practice, retinoblastoma can sometimes be misdiagnosed and mismanaged, leading to extraocular extension even death. In this report, series of 3 cases are related that emphasize the conditions consequences resulting from misdiagnosis mismanagement retinoblastoma. The features, imaging findings, histopatholigical examination, management case reports children with presented. Two received pars plana vitrectomy...
Total rupture of extraocular muscles is an infrequent clinical finding. Here we conducted this retrospective study to evaluate their causes injury, features, imaging, surgical management, and final outcomes in cases isolated muscle at a tertiary center China. Thirty-six patients were identified (24 men 12 women). Mean age was 34 years (range 2–60). The right eye involved 21 the left 1 15. A sharp object or metal hook cause lesion 16 patients, sinus surgery 14 traffic accident 3 orbital 2...
Although there were many prior studies about exotropia, few focused on large-angle intermittent exotropia. The goal of this study was to evaluate single-stage surgical outcomes for exotropia and analyze risk factors that may affect the success surgery. Records from patients with exodeviations >60 prism diopters(PD) who surgically treated at Zhongshan Ophthalmic Center, Sun Yat-Sen University reviewed. Included within review data on, pre- post-operative ocular motility, primary alignment,...
Purpose: Intraorbital foreign body is relatively rare and therefore often misdiagnosed in clinical practice. The purpose of this report to summarize the features intraorbital bodies their surgical management. Methods: A retrospective study cases. Clinical manifestations, imaging findings, treatments patients with bodies, who were seen at Zhongshan Ophthalmic Center Sun Yat-sen University between January 2002 July 2013, retrospectively reviewed. Results: Of 22 cases reviewed, 19 men 3 women a...
The genetic defects underlying approximately half of all retinitis pigmentosa (RP) cases are unknown. A number genes responsible for Leber congenital amaurosis (LCA) may also cause RP when they mutated. Our previous study revealed that variants in the most frequently mutated nine exons accounted mutations detected a cohort patients with LCA. aim present was to detect LCA-associated using two different strategies. Sanger sequencing used screen 293 and exome 12 157 then validate by sequencing....
Background: Even with drug-eluting stents, the risk of in-stent restenosis (ISR) remains high. The goal this study was to investigate use an endothelial progenitor cell (EPC) capture stent plus regional EPC transplantation reduce ISR rate. Methods: Endothelial stents were fabricated using fibrin gel and anti-CD34 anti-VEGFR-2 dual antibodies. Twenty male New Zealand white rabbits established as atherosclerotic model randomly divided into two groups: group 1 (n = 10), in which deployed right...
AbstractPurpose To describe the refractive profile of surgical patients with intermittent exotropia (IXT) residing in southern China.Methods Medical records who received strabismus surgery between June 2014 and August 2020 were retrospectively reviewed. Clinical data, including age, sex, errors, preoperative angle deviation, types exotropia, accommodative convergence to accommodation ratio (AC/A ratio) stereopsis, investigated.Results A total 2250 included, 93.6% younger than 30 years age....
Purpose: The purpose of this study was to design an objective method for measurement head positions as achieved with use a microelectromechanical systems (MEMS) sensor. In addition, system observe the abnormal position (AHP) in patients congenital superior oblique palsy (SOP) before and after their surgery. Methods: An MEMS sensor designed recording pitch, roll, yaw values real time. then fixed on synoptophore from –30 degrees +30 horizontally vertically test accuracy these measurements....
Mutations in the crumbs homolog (CRB)1 gene are among common causes of severe early onset retinal dystrophy. Some characteristic clinical phenotypes frequently associated with mutations CRB1. The aim this study was to examine whether phenotype-directed mutational screening facilitated detection CRB1 mutations. included 22 probands at least one potential CRB1-associated for Variants were detected using Sanger sequencing. complete sequences coding and adjacent intronic regions analyzed,...