A5003376619- Nanoplatforms for cancer theranostics
- Luminescence Properties of Advanced Materials
- Luminescence and Fluorescent Materials
- Advanced biosensing and bioanalysis techniques
- RNA Interference and Gene Delivery
- Advanced Nanomaterials in Catalysis
- Nanoparticle-Based Drug Delivery
- Photoacoustic and Ultrasonic Imaging
- Phase Change Materials Research
- Lanthanide and Transition Metal Complexes
- RNA and protein synthesis mechanisms
- Molecular Sensors and Ion Detection
- Block Copolymer Self-Assembly
- Radiation Detection and Scintillator Technologies
- Polysaccharides and Plant Cell Walls
- Advanced Photocatalysis Techniques
- Solar Thermal and Photovoltaic Systems
- DNA and Nucleic Acid Chemistry
- Natural product bioactivities and synthesis
- Sulfur Compounds in Biology
- Photodynamic Therapy Research Studies
- Adsorption and Cooling Systems
- Polymer crystallization and properties
- Quantum Dots Synthesis And Properties
- Gut microbiota and health
Capital Normal University
2016-2025
Jiangxi Science and Technology Normal University
2025
Stomatology Hospital
2022-2025
Fujian Agriculture and Forestry University
2023-2025
Wuhan University of Technology
2023-2025
Kunming Medical University
2021-2025
Fudan University
2007-2024
Sichuan University
2017-2024
ShenZhen People’s Hospital
2024
Army Medical University
2021-2024
A novel method of rare-earth cation-assisted ligand assembly has been developed to provide upconversion nanophosphors with T(1)-enhanced magnetic resonance (MR), radioactivity, and targeted recognition properties, making these nanoparticles potential candidates for multimodal bioimaging. The process modifying the surface confirmed by transmission electron microscopy, X-ray powder diffraction, photoelectron spectroscopy, proton nuclear resonance, Fourier-transform infrared energy-dispersive...
Uniform silica-coated NaYF(4): 20 mol % Yb, 2 Er nanocomposites with good dispersibility, containing organic dye incorporated in the silica shell and folic acid conjugated on surface of shell, were prepared characterized. The core-shell are 20-22 nm size, water soluble, buffer stable, photostability biocompatibility. Folic (FA) offers a means targeting human cells that greatly overexpress folate receptor (FR). By use confocal microscopy quantitative flow cytometry analysis, we demonstrate...
Abstract Because of the extreme toxicity cyanide anions, a great deal effort has been invested in developing probes that use colorimetric and fluorometric methods to detect them. To date, most current optical require organic solvents or mixture water. Upconversion nanophosphors (UCNPs) can serve as excellent emitters result their sharp emission peaks simple control wavelength. Here, fabrication hybrid material composed iridium complex UCNPs anions selectively pure water is described. In...
Photothermal therapy (PTT), a new, noninvasive treatment measure, has recently drawn much attention. However, due to the limited penetration depth of near‐infrared (NIR) light, PTT is focused on treating superficial tumors. Improving therapeutic effect bottleneck for successful PTT. To solve this problem, new kind nanoplatform (Nanogel+phenylethynesulfonamide (PES)) fabricated by using thermo‐responsive polymer shell (poly( N ‐isopropylacrylamide‐co‐acrylic acid) encapsulate 2‐PES, an...
Imaging‐guided photothermal therapy based on functional nanomaterials has recently received significant attention and the selection of materials with optimal imaging effect is extremely important. In this work, NaDyF 4 ‐based nanoparticles varying size are synthesized by doping different amounts lutetium ions. To obtain an optimized material, influence factor magnetic resonance, X‐ray attenuation, properties discussed in detail. Then, :50%Lu@Prussian blue (PB) nanocomposite selected as...
Synergistic therapy is an accepted method of enhancing the efficacy cancer therapies. In this study, cypate‐conjugated porous NaLuF 4 doped with Yb 3+ , Er and Gd synthesized its potential for upconversion luminescence/magnetic resonance dual‐modality molecular imaging guiding oncotherapy tested. Loading nanoparticles (UCNP‐cy) small interfering RNA gene against heat shock protein 70 (UCNP‐cy‐siRNA) enhances cell damage. UCNP‐cy‐siRNA exhibits remarkable antitumor in vivo as a result...
Photothermal therapy (PTT) is a potentially advanced strategy for highly precise cancer treatment. Tumor-microenvironment-activatable agents provide useful tools PTT, but their photothermal conversion capacities vary and cannot be evaluated in vivo; thus, general PTT prescription does not work with individual activatable agents. Here, glutathione (GSH)-activatable nanocomposites, silicomolybdate-functionalized NaLuF4 :Yb,Er@NaLuF4 @NaLuF4 :Nd are prepared, customized of subcutaneous...
Hydrogel functionalization with DNA aptamers can be applied for developing a novel sustained-release system.
Mesoporous silica encapsulating upconversion luminescence NaYF(4) nanorods with uniform core-shell structures have been successfully synthesized by the surfactant-assistant sol-gel process. The thickness of ordered mesoporous shells can be adjusted from 50 to 95 nm varying amount hydrolyzed silicate oligomer precursors tetraethyl orthosilicate (TEOS), which further influences BET surface area, pore volume, and intensity. After coated shells, hydrophobic is rendered hydropholic...
A folate-functionalized degradable amphiphilic dendrimer-like star polymer (FA-DLSP) with a well-defined poly(L-lactide) (PLLA) core and six hydrophilic polyester dendrons based on 2,2-bis(hydroxymethyl) propionic acid was successfully synthesized to be used as nanoscale carrier for cancer cell-targeted drug delivery. This FA-DLSP hybrid formed unimolecular micelles in the aqueous solution mean particle size of ca. 15 nm determined by dynamic light scattering transmission electron...