A5071983387- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Medical Imaging and Pathology Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Tracheal and airway disorders
- Pleural and Pulmonary Diseases
- Venous Thromboembolism Diagnosis and Management
- Radiomics and Machine Learning in Medical Imaging
- Occupational and environmental lung diseases
- Medical Imaging Techniques and Applications
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Trauma Management and Diagnosis
- Aortic aneurysm repair treatments
- Radiation Dose and Imaging
- Aortic Disease and Treatment Approaches
- Lung Cancer Research Studies
- Ultrasound in Clinical Applications
- Renal and Vascular Pathologies
- Advanced X-ray and CT Imaging
- Cardiac tumors and thrombi
- Abdominal Trauma and Injuries
- Central Venous Catheters and Hemodialysis
- Vascular Anomalies and Treatments
- Respiratory Support and Mechanisms
- Esophageal and GI Pathology
Centre Hospitalier Universitaire de Grenoble
2015-2024
Université Grenoble Alpes
2015-2024
Imagerie Médicale et Radiothérapie Drôme Ardèche
2007-2023
Institut pour l'avancée des biosciences
2010-2023
Hôpital Albert Michallon
2008-2023
Inserm
2013-2023
Commissariat à l'Énergie Atomique et aux Énergies Alternatives
2023
Brain Tech Laboratory
2023
CEA Grenoble
2023
Institut polytechnique de Grenoble
2023
<h3>Importance</h3> Interpretation of chest radiographs is a challenging task prone to errors, requiring expert readers. An automated system that can accurately classify may help streamline the clinical workflow. <h3>Objectives</h3> To develop deep learning–based algorithm normal and abnormal results from with major thoracic diseases including pulmonary malignant neoplasm, active tuberculosis, pneumonia, pneumothorax validate algorithm's performance using independent data sets. <h3>Design,...
•Vemurafenib monotherapy is effective for BRAFV600-mutated NSCLC.•Vemurafenib not BRAFnonV600-mutated a treatment option NSCLC patients when the dabrafenib/trametinib combination feasible or reimbursed.•Routine biomarker screening of should include BRAFV600 mutations. BackgroundBRAF mutations occurring in 1%–5% with non-small-cell lung cancer (NSCLC) are therapeutic targets these cancers but impact exact mutation on clinical activity unclear. The French National Cancer Institute (INCA)...
Objective: The purpose of this study was to describe a blinded intra-aortic balloon occlusion (IABO) procedure in pelvic fractures (PF) for patients with critically uncontrollable hemorrhagic shock (CUHS). Methods: Of 2,064 treated PF, 13 underwent IABO during initial resuscitation control massive bleeding leading CUHS. Our consists internal aortic without fluoroscopy, using latex inflated the infrarenal aorta. Retrospectively collected data included demographics, fracture classification,...
While microgravity exposure is known to cause deterioration of skeletal muscle performance, little regarding its effect on tendon structure and function. Hence, the aims this study were investigate effects simulated mechanical properties human assess effectiveness resistive countermeasures in preventing any detrimental effects. Eighteen men (aged 25-45 yr) underwent 90 days bed rest: nine performed exercise during period (BREx group), rest only (BR group). Calf-raise leg-press exercises...
PURPOSE: To assess prospectively the clinical effectiveness of helical computed tomography (CT) in evaluation patients with unresolved suspicion for pulmonary embolism (PE). MATERIALS AND METHODS: Helical CT was performed 164 consecutive suspected having acute PE, intermediate probability at ventilation-perfusion (V-P) scintigraphy, and normal findings duplex ultrasonography (US) legs. Fifteen also underwent angiography. results were analyzed immediately to help plan anticoagulant treatment....
Anatomical pharyngeal and craniofacial abnormalities have been reported using upper airway imaging in snorers with or without obstructive sleep apnoea (OSA). However, the influences of age weight patient on these remain to be established. The aim this study was, therefore, evaluate a large population OSA, relationship between body mass index (BMI), morphology. One hundred forty patients were referred for assessment possible sleep-related breathing disorder had complete polysomnography,...
Despite advances in cancer therapy, mortality is still high except early-stage tumors, and screening remains a challenge. The randomized National Lung Screening Trial (NLST), comparing annual low-dose computed tomography (LDCT) chest X-rays, revealed 20% decrease lung-cancer-specific mortality. These results raised numerous questions. French intergroup for thoracic oncology the French-speaking group convened an expert to provide coherent outlook on modalities France.A literature review was...
The association between pleural plaques and mesothelioma remains controversial. present study was designed to examine the on computed tomography (CT) scan risk of in a follow-up asbestos-exposed workers.Retired or unemployed workers previously occupationally exposed asbestos were invited participate screening program for asbestos-related diseases, including CT scan, organized October 2003 December 2005 four regions France. Randomized, independent, double reading scans by panel seven chest...
BackgroundIodinated and gadolinium-based contrast media (ICM; GBCM) induce immediate hypersensitivity (IH) reactions. Differentiating allergic from non-allergic IH is crucial; allergy contraindicates the culprit agent for life. We studied frequency of among ICM or GBCM reactors.MethodsPatients were recruited in 31 hospitals between 2005 2009. Clinical symptoms, plasma histamine tryptase concentrations skin tests recorded. Allergic was diagnosed by intradermal (IDT) with CM diluted 1:10,...
Rationale: Management of first episodes primary spontaneous pneumothorax remains the subject debate. Objectives: To determine whether first-line simple aspiration is noninferior to chest tube drainage for lung expansion in patients with complete pneumothorax. Methods: We conducted a prospective, open-label, randomized noninferiority trial. Adults aged 18-50 years (total separation from wall), recruited at 31 French hospitals 2009 2015, received (n = 200) or 202) as treatment. The outcome was...
This paper describes research work motivated by an innovative medical application: computer-assisted transbronchial biopsy. project involves the registration, with no external localization device, of a preoperative three-dimensional (3-D) computed tomography (CT) scan thoracic cavity (showing tumor that requires needle biopsy), and intraoperative endoscopic two-dimensional (2-D) image sequence, in order to provide assistance puncture tumor. Because specific difficulties resulting from data...
BACKGROUND: Assessments of the upper airways in patients with obstructive sleep apnoea syndrome are usually carried out on awake who upright. The dynamics airway a patient is asleep and lying down may be different. METHODS: Somnofluoroscopy, computed tomography airway, cephalometry were 11 (10 male; mean (SD) age 53 (10) years) to examine while they asleep. RESULTS: At somnofluoroscopy 10 stage 2 only one REM sleep. least five events visualised by lateral fluoroscopy each patient. Imaging...
The purpose of this report is to describe an original 3D technique that permits bronchoscopic perspective simulations the tracheobronchial tree on affordable workstation. Software based surface shading was developed permit navigation through central airways using spiral CT data. Multiplanar reformations are displayed simultaneously with virtual bronchoscopy give information about tissues surrounding airways. Two clinical examples reported illustrate value advanced computer technique.