A5000974741- Health Systems, Economic Evaluations, Quality of Life
- Pharmaceutical Economics and Policy
- Meta-analysis and systematic reviews
- Ethics in Clinical Research
- Retinal and Optic Conditions
- Vasculitis and related conditions
- Intraocular Surgery and Lenses
- Retinal and Macular Surgery
- Ocular Diseases and Behçet’s Syndrome
- Retinal Diseases and Treatments
- Biomedical Ethics and Regulation
- Pharmaceutical studies and practices
- Tuberculosis Research and Epidemiology
- Health and Medical Research Impacts
- Vascular Malformations Diagnosis and Treatment
- Healthcare Systems and Reforms
- Obstructive Sleep Apnea Research
- Statistical Methods in Clinical Trials
- Drug-Induced Hepatotoxicity and Protection
- Pneumonia and Respiratory Infections
- Cardiac Valve Diseases and Treatments
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Intellectual Property and Patents
- Innovations in Medical Education
- Diversity and Career in Medicine
Thomas Jefferson University
2020-2022
Wills Eye Hospital
2020-2022
Yale University
2015-2018
All India Institute of Medical Sciences
2015
Center for Clinical Research (United States)
2014
University of the Sciences
2013
University of Pennsylvania
2013
Rationale: Intensive care unit (ICU)-based randomized clinical trials (RCTs) among adult critically ill patients commonly fail to detect treatment benefits.Objectives: Appraise the rates of success, outcomes used, statistical power, and design characteristics published trials.Methods: One hundred forty-six ICU-based RCTs diagnostic, therapeutic, or process/systems interventions from January 2007 May 2013 in 16 high-impact general critical journals were studied.Measurement Main Results: Of...
Registration of clinical trials is critical for promoting transparency and integrity in medical research; however, must be registered a prospective fashion to deter unaccounted protocol modifications or selection alternate outcomes that may enhance favorability reported findings. We assessed adherence the International Committee Medical Journal Editors' (ICMJE) registration policy identified frequency registrations occurring after potential observation primary outcome data among published...
Although the peer review process is believed to ensure scientific rigor, enhance research quality, and improve manuscript clarity, many investigators are concerned that too slow, expensive, unreliable, static. In this feasibility study, we sought survey corresponding authors of recently published clinical studies on speed efficiency publication process. Web-based a 20% random sample in MEDLINE-indexed journals with Ovid MEDLINE entry dates between December 1 15, 2016. Survey addressed...
To determine factors associated with loss of good vision (defined as Snellen visual acuity [VA] < 20/40) after surgery among eyes presenting macula-on primary rhegmatogenous retinal detachment (RRD) initial VA ≥20/40.Multicenter, retrospective, cohort study undergoing scleral buckle (SB), pars plana vitrectomy (PPV), or combined vitrectomy/scleral (PPV/SB) for non-complex RRD ≥20/40.Among 646 RRDs ≥20/40, 106 (16.4%) had <20/40 (i.e. lost vision) at final follow-up. Eyes losing slightly...
Background : our objective was to determine the incidence of toxicity among veterans initiating isoniazid therapy for latent tuberculosis infection (LTBI) and whether advancing age a risk factor toxicity. Methods we performed retrospective cohort study all adults treatment LTBI at Veterans Medical Center from 1999 2005. We collected data on patient demographics, co-morbidities, site initiation, outcome. Results 219 patients initiated during period observation, completion confirmed in 100...
Left ventricular outflow tract obstruction (LVOTO) has been reported with bio-prosthetic and mechanical mitral valves (MV), though it is more common the former. The can be dynamic or fixed. We hereby report a case of fixed LVOTO following MV replacement (MVR).
Sarcoidosis, an idiopathic systemic disorder characterized by noncaseating granulomas, is often associated with granulomatous uveitis. Anterior segment involvement can present mutton-fat keratic precipitates, anterior chamber cell, and iris nodules. Sarcoid posterior uveitis may vitritis, retinal vasculitis, choroidal lesions.Sarcoid-associated vasculitis classically thought of as predominantly involving veins, but in this case report we describe a 76-year-old Caucasian woman presenting...
Problem Health disparities among racial and ethnic groups exist in the United States despite improvements health status access to care. These inequalities may be reduced by increasing minority physician recruitment; however, how best recruit these physicians remains unclear. Approach Near-peer teachers are not professionally trained, but have recently learned material that they themselves teach. teaching student outreach programs effective recruitment. The authors used a near-peer model...