Matthew R. Starr

ORCID: 0000-0002-3021-5630
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About
Contact & Profiles
Research Areas
  • Retinal and Macular Surgery
  • Intraocular Surgery and Lenses
  • Retinal Diseases and Treatments
  • Retinal and Optic Conditions
  • Retinal Imaging and Analysis
  • Glaucoma and retinal disorders
  • Vascular Malformations Diagnosis and Treatment
  • Ocular Diseases and Behçet’s Syndrome
  • Artificial Intelligence in Healthcare and Education
  • Corneal surgery and disorders
  • Ocular Infections and Treatments
  • Opioid Use Disorder Treatment
  • Acute Ischemic Stroke Management
  • Ophthalmology and Visual Impairment Studies
  • Traumatic Ocular and Foreign Body Injuries
  • Pain Management and Opioid Use
  • Anesthesia and Pain Management
  • Cerebral Venous Sinus Thrombosis
  • Cerebrovascular and Carotid Artery Diseases
  • Dermatological and Skeletal Disorders
  • Systemic Lupus Erythematosus Research
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Vasculitis and related conditions
  • Bartonella species infections research
  • COVID-19 diagnosis using AI

Mayo Clinic
2016-2025

Mayo Clinic in Arizona
2019-2024

University of Pittsburgh Medical Center
2024

WinnMed
2021-2024

Wills Eye Hospital
2020-2023

Thomas Jefferson University
2020-2023

UPMC Health System
2023

Allergan (Ireland)
2022

Health First
2021

Jefferson University Hospitals
2020

ObjectiveTo assess the quality, empathy, and safety of expert edited large language model (LLM), human created LLM responses to common retina patient questionsDesignRandomized, masked multicenter studyParticipantsTwenty-one questions were randomly assigned among 13 specialists. Each a response (Expert) then (ChatGPT-4)-generated that question (Expert+AI), timing themselves for both tasks. Five LLMs (ChatGPT-3.5, ChatGPT-4, Claude 2, Bing, Bard) also generated each question. The original...

10.1016/j.xops.2024.100485 article EN cc-by-nc-nd Ophthalmology Science 2024-02-06

ObjectiveTo determine the appropriateness of ophthalmology recommendations from an online chat-based artificial intelligence model to questions.Patients and MethodsCross-sectional qualitative study April 1, 2023, 30, 2023. A total 192 questions were generated spanning all ophthalmic subspecialties. Each question was posed a large language (LLM) 3 times. The responses graded by appropriate subspecialists as appropriate, inappropriate, or unreliable in 2 grading contexts. first context if...

10.1016/j.mcpdig.2024.01.003 article EN cc-by-nc-nd Mayo Clinic Proceedings Digital Health 2024-02-15

Specialized ophthalmology terminology limits comprehension for nonophthalmology clinicians and professionals, hindering interdisciplinary communication patient care. The clinical implementation of large language models (LLMs) into practice has to date been relatively unexplored. To evaluate LLM-generated plain summaries (PLSs) integrated standard notes (SONs) in improving diagnostic understanding, satisfaction, clarity. Randomized quality improvement study conducted from February 1, 2024,...

10.1001/jamaophthalmol.2025.0351 article EN JAMA Ophthalmology 2025-04-03

PurposeTo investigate the effect of coronavirus disease 2019 (COVID-19) pandemic on clinical presentation acute, primary rhegmatogenous retinal detachment (RRD).DesignSingle-center, consecutive case series with historical controls.ParticipantsConsecutive patients seeking treatment for RRD in a 50-day period during COVID-19 (March 9–April 27, 2020) and corresponding previous year 4–April 22, 2019) United States.MethodsThe cohorts were compared to assess demographic variables presentations....

10.1016/j.ophtha.2020.10.009 article EN other-oa Ophthalmology 2020-10-13

Current studies assessing the risk of stroke, myocardial infarction (MI), and death in patients undergoing intravitreal anti-vascular endothelial growth factor (VEGF) therapy are inconclusive. To our knowledge, no population-based have been performed to examine these potential risks.To whether with exudative age-related macular degeneration (AMD) receiving anti-VEGF injections a higher incidence MI, or compared control populations.This population-based, retrospective cohort study included...

10.1001/jamaophthalmol.2018.6891 article EN JAMA Ophthalmology 2019-01-31

Rhegmatogenous retinal detachments with inferior breaks are believed to have a higher risk of recurrent rhegmatogenous detachment. This study compared anatomic and visual outcomes between primary pars plana vitrectomy (PPV) combination PPV scleral buckle (PPV/SB) for breaks.This is an analysis the Primary Retinal Detachment Outcomes study, multi-institutional cohort consecutive detachment surgeries from January 1, 2015, through December 31, 2015. The outcome was single-surgery success rate....

10.1097/iae.0000000000002917 article EN Retina 2020-07-23

Background: While large language models (LLMs) are increasingly used in medicine, their effectiveness compared with human experts remains unclear. This study evaluates the quality and empathy of Expert + AI, experts, LLM responses neuro-ophthalmology. Methods: randomized, masked, multicenter cross-sectional was conducted from June to July 2023. We randomly assigned 21 neuro-ophthalmology questions 13 experts. Each expert provided an answer then edited a ChatGPT-4–generated response, timing...

10.1097/wno.0000000000002145 article EN Journal of Neuro-Ophthalmology 2024-04-02

Background: Successful recanalization following endovascular thrombectomy (EVT) in vertebrobasilar artery occlusions (VBAOs) does not uniformly translate into favorable functional outcomes. Identifying predictors of futile is critical for improving patient selection and treatment strategies. This study aimed to compare patients with good versus poor outcomes despite successful VBAO establish predictive factors recanalization. Methods: We retrospectively analyzed who achieved after EVT from a...

10.1161/str.56.suppl_1.tmp78 article EN Stroke 2025-01-30

Background: The effect of renal dysfunction on early infarct growth rate (IGR) in anterior circulation large vessel occlusion (ACLVO) stroke is not well studied. This study aimed to explore the association between creatinine-based biomarkers dysfunction, fast or slow progressor phenotypes ACLVO stroke, and related clinical outcomes. Methods: retrospective examined patients with acute intracranial internal carotid artery middle cerebral M1 occlusions admitted 2014 2019. Patients were included...

10.1161/str.56.suppl_1.wp88 article EN Stroke 2025-01-30

Background: Endovascular therapy (EVT) has emerged as a first-line intervention for vertebrobasilar artery occlusion (VBAO) patients, supported by two recent landmark randomized controlled trials. However, EVT outcomes may vary based on patient age and collateral status. This study examines the interaction between status in VBAO patients. Methods: We retrospectively analyzed patients who underwent from prospectively maintained database January 2014 2024. Patients were categorized into...

10.1161/str.56.suppl_1.dp38 article EN Stroke 2025-01-30

Purpose: To report the anatomic and visual outcomes of eyes developing delayed rhegmatogenous retinal detachment (RRD) post macular surgery. Methods: This was a retrospective, multicentric study including undergoing RRD repair at least 3 months after surgery for either full-thickness hole (FTMH) or epiretinal membrane (ERM). Anatomic functional assessment, i.e., pre- post-operative best corrected acuity (BCVA), indications details surgery, time interval from to RRD, intraocular tamponade,...

10.1097/iae.0000000000004433 article EN Retina 2025-02-19
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