Sophie J. Bakri

ORCID: 0000-0002-0887-3194
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About
Contact & Profiles
Research Areas
  • Retinal Diseases and Treatments
  • Retinal and Optic Conditions
  • Glaucoma and retinal disorders
  • Retinal Imaging and Analysis
  • Retinal and Macular Surgery
  • Ocular Diseases and Behçet’s Syndrome
  • Intraocular Surgery and Lenses
  • Ocular Infections and Treatments
  • Retinal Development and Disorders
  • Ocular Oncology and Treatments
  • Health Systems, Economic Evaluations, Quality of Life
  • Meta-analysis and systematic reviews
  • Vascular Malformations Diagnosis and Treatment
  • Cerebral Venous Sinus Thrombosis
  • Diversity and Career in Medicine
  • Ophthalmology and Visual Impairment Studies
  • Sinusitis and nasal conditions
  • Clinical practice guidelines implementation
  • Optical Coherence Tomography Applications
  • melanin and skin pigmentation
  • Drug-Induced Ocular Toxicity
  • Angiogenesis and VEGF in Cancer
  • scientometrics and bibliometrics research
  • Artificial Intelligence in Healthcare and Education
  • Statistical Methods in Clinical Trials

Mayo Clinic in Arizona
2015-2025

Mayo Clinic
2015-2024

WinnMed
2013-2024

Hasanuddin University
2024

University of Minnesota Rochester
2008-2022

Ophthalmology Associates (United States)
2009-2019

Mayo Clinic in Florida
2015-2017

Research to Prevent Blindness
2013-2015

St. Luke's Hospital
2015

Allergan (Ireland)
2013

In Brief Purpose: To review evidence and provide updated guidelines on intravitreal (IVT) injection technique monitoring. Methods: A of the published literature IVT from 2004 to 2014 formed basis for round table deliberations by an expert panel ophthalmologists. Results: The dramatic increase in number injections has been accompanied a comparable surrounding practice patterns techniques. identified areas that have evolved since publication original 2004, most notable which were lack support...

10.1097/iae.0000000000000399 article EN Retina 2014-12-01

<h3>Importance</h3> The Diabetic Retinopathy Clinical Research Network (DRCR Network), sponsored by the National Eye Institute, reported results of a comparative effectiveness randomized clinical trial (RCT) evaluating 3 anti–vascular endothelial growth factor (anti-VEGF) agents aflibercept (2.0 mg), bevacizumab (1.25 and ranibizumab (0.3 mg) for treatment diabetic macular edema (DME) involving center retina associated with visual acuity loss. many important findings RCT prompted American...

10.1001/jamaophthalmol.2015.4110 article EN JAMA Ophthalmology 2015-10-29

Purpose: To identify the microvascular changes associated with paracentral acute middle maculopathy (PAMM) and macular neuroretinopathy (AMN) to improve our understanding of relevant involvement three retinal capillary plexuses using projection-resolved optical coherence tomography angiography (PR-OCTA). Methods: This was a retrospective study 18 eyes AMN or PAMM imaged OCTA. We used cross-sectional PR-OCTA localize reduced flow signal superficial (SCP), (MCP), deep plexus (DCP)...

10.1167/iovs.18-24112 article EN cc-by-nc-nd Investigative Ophthalmology & Visual Science 2018-06-06

Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD), characterized by atrophic lesions that first start in the outer retina and progressively expand to cover macula fovea, center macula, leading irreversible loss vision over time. GA distinct from wet or neovascular AMD (nAMD), other AMD. Neovascular new invading leaky blood vessels can lead acute loss. nAMD may coexist same eye. The underlying pathophysiology complex thought involve chronic inflammation due...

10.18553/jmcp.2023.29.5-a.s2 article EN Journal of Managed Care & Specialty Pharmacy 2023-05-01

ObjectiveTo assess the quality, empathy, and safety of expert edited large language model (LLM), human created LLM responses to common retina patient questionsDesignRandomized, masked multicenter studyParticipantsTwenty-one questions were randomly assigned among 13 specialists. Each a response (Expert) then (ChatGPT-4)-generated that question (Expert+AI), timing themselves for both tasks. Five LLMs (ChatGPT-3.5, ChatGPT-4, Claude 2, Bing, Bard) also generated each question. The original...

10.1016/j.xops.2024.100485 article EN cc-by-nc-nd Ophthalmology Science 2024-02-06

ObjectiveTo determine the appropriateness of ophthalmology recommendations from an online chat-based artificial intelligence model to questions.Patients and MethodsCross-sectional qualitative study April 1, 2023, 30, 2023. A total 192 questions were generated spanning all ophthalmic subspecialties. Each question was posed a large language (LLM) 3 times. The responses graded by appropriate subspecialists as appropriate, inappropriate, or unreliable in 2 grading contexts. first context if...

10.1016/j.mcpdig.2024.01.003 article EN cc-by-nc-nd Mayo Clinic Proceedings Digital Health 2024-02-15

Specialized ophthalmology terminology limits comprehension for nonophthalmology clinicians and professionals, hindering interdisciplinary communication patient care. The clinical implementation of large language models (LLMs) into practice has to date been relatively unexplored. To evaluate LLM-generated plain summaries (PLSs) integrated standard notes (SONs) in improving diagnostic understanding, satisfaction, clarity. Randomized quality improvement study conducted from February 1, 2024,...

10.1001/jamaophthalmol.2025.0351 article EN JAMA Ophthalmology 2025-04-03

To ascertain whether a single 4-mg intravitreal triamcinolone acetonide injection is associated with elevated intraocular pressure (IOP).Retrospective noncomparative interventional case series. Forty-three consecutive eyes of 38 patients who had 12 weeks follow-up were included. The IOPs before and after treatment recorded by Goldmann applanation at each patient visit.Within injection, 21 43 (48.8%) demonstrated an increase in IOP 5 mm Hg or greater, (27.9%) 10 greater. mean time for greater...

10.3928/1542-8877-20030901-08 article EN Ophthalmic surgery, lasers & imaging retina 2003-09-01

10.1007/s00417-008-0819-2 article EN Graefe s Archive for Clinical and Experimental Ophthalmology 2008-04-18

In Brief Purpose: To present the finding of tiny silicone oil droplets in 15 eyes patients after intravitreal injections an anti–vascular endothelial growth factor agent or triamcinolone acetonide and to discuss likely source oil. Methods: observational case series, charts who had undergone by one surgeon were reviewed retrospectively. The was noted. following information also documented: number type before appearance droplets, symptoms evidence ocular inflammation, visual acuity length...

10.1097/iae.0b013e31816c6868 article EN Retina 2008-07-01

10.1007/s00417-007-0754-7 article EN Graefe s Archive for Clinical and Experimental Ophthalmology 2008-01-16
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