- Retinal Diseases and Treatments
- Retinopathy of Prematurity Studies
- Glaucoma and retinal disorders
- Retinal and Optic Conditions
- Retinal Imaging and Analysis
- Retinal and Macular Surgery
- Intraocular Surgery and Lenses
- Neonatal Respiratory Health Research
- Ocular Oncology and Treatments
- Neonatal and fetal brain pathology
- Retinal Development and Disorders
- Ocular Diseases and Behçet’s Syndrome
- Ocular Infections and Treatments
- Ophthalmology and Visual Impairment Studies
- Preterm Birth and Chorioamnionitis
- Photodynamic Therapy Research Studies
- Cardiovascular Conditions and Treatments
- Child Abuse and Related Trauma
- Photoacoustic and Ultrasonic Imaging
- Optical Coherence Tomography Applications
- Traumatic Ocular and Foreign Body Injuries
- Nanoplatforms for cancer theranostics
- Neonatal Health and Biochemistry
- Drug-Induced Ocular Toxicity
- Restraint-Related Deaths
Stanford University
2016-2025
Smith-Kettlewell Eye Research Institute
2016-2025
Palo Alto University
2007-2024
Palo Alto Institute
2011-2021
Stanford Medicine
2003-2018
Lucile Packard Children's Hospital
2018
Topcon (Netherlands)
2016
Menlo School
2008-2010
Colégio Brasileiro de Cirurgiões
2009
Cleveland Eye Clinic
2001-2008
Laser photocoagulation, which is the standard treatment for retinopathy of prematurity (ROP), can have adverse events. Studies anti-vascular endothelial growth factor injections suggested efficacy in ROP, but few studies directly compared them with laser treatments.To compare intravitreal aflibercept vs photocoagulation infants ROP requiring treatment.This noninferiority, phase 3, 24-week, randomized clinical trial was conducted 27 countries (64 hospital sites) throughout Asia, Europe, and...
Retinopathy of prematurity (ROP) is a leading cause blindness in premature and low birth weight infants. Here, the authors examine incidence ROP United States evaluate risk factors associated with development.The National Healthcare Cost Utilization Project Kids' Inpatient Database was queried for all newborns without ROP. Adjusted odds ratios were constructed predictors using multivariate logistic regression modeling.The increased from 14.70% 2000 to 19.88% 2012. Multivariate analysis...
Optical coherence tomography (OCT) is a powerful biomedical imaging technology that relies on the coherent detection of backscattered light to image tissue morphology in vivo. As consequence, OCT susceptible noise (speckle noise), which imposes significant limitations its diagnostic capabilities. Here we show method based purely manipulation able entirely remove speckle originating from turbid samples without any compromise resolution. We refer this as Speckle-Free (SFOCT). Using SFOCT,...
We developed a photoacoustic ocular imaging device and demonstrated its utility in the deeper layers of eye including retina, choroid, optic nerve. Using safe laser intensity, system was able to visualize blood distribution an enucleated pig's living rabbit. Ultrasound images, which were simultaneously acquired, overlaid on images eye's anatomy. Such may be used future for early detection improved management neovascular diseases, wet age-related macular degeneration proliferative diabetic...
Purpose: To understand factors associated with poor attendance of follow-up appointments for care glaucoma (GL), AMD, and diabetic retinopathy (DR) in a tertiary referral center, to identify strategies improve adherence. Methods: Cross-sectional study 240 adults attending GL, or DR. Cases (N = 102) were patients who missed failed reschedule an appointment within 1 month the recommended date during preceding year. Controls 138) completed assigned follow-up. Data regarding impacting adherence...
To validate a vascular severity score as an appropriate output for artificial intelligence (AI) Software Medical Device (SaMD) retinopathy of prematurity (ROP) through comparison with ordinal disease labels stage and plus assigned by the International Classification Retinopathy Prematurity, Third Edition (ICROP3), committee.Validation study AI-based ROP score.A total 34 experts from ICROP3 committee.Two separate datasets 30 fundus photographs each (0-5) (plus, preplus, neither) were labeled...
X-linked cone dystrophy is a type of hereditary retinal degeneration characterized by progressive dysfunction the day vision or photopic (cone) system with preservation night scotopic (rod) function. The disease presents triad photophobia, loss color and reduced central vision. This phenotype distinct from retinitis pigmentosa (RP) in which there are prominent peripheral disturbances. genetically heterogeneous disorder, linkage to loci on Xp11.4–Xp21.1 (COD1, OMIM 304020) Xq27 (COD2,...
<h3>Aims</h3> To determine the incidence of retinopathy prematurity (ROP) based upon a national database and to identify baseline characteristics, demographic information, comorbidities, surgical interventions. <h3>Methods</h3> The National Inpatient Sample, representative sample all US hospital discharges from 1997 2002, was queried for newborn infants with without ROP. Primary outcome variables included demographics, length stay (LOS), charges. Multivariate logistic regression used predict...
BACKGROUND AND OBJECTIVE: To report the 5-year results of Stanford University Network for Diagnosis Retinopathy Prematurity (SUNDROP) telemedicine initiative. PATIENTS METHODS: Infants requiring retinopathy prematurity (ROP) screening at six neonatal intensive care units from December 1, 2005, to November 30, 2010, were evaluated with remote retinal photography by an ROP specialist. Every infant received outpatient binocular indirect ophthalmoscope examinations until termination criteria...
BackgroundAge-related macular degeneration (AMD) is a leading cause of visual loss among the elderly. A key cell type involved in AMD, retinal pigment epithelium, expresses G protein–coupled receptor that, response to its ligand, L-DOPA, up-regulates epithelia–derived factor, while down-regulating vascular endothelial growth factor. In this study we investigated potential relationship between L-DOPA and AMD.MethodsWe used retrospective analysis compare incidence AMD patients taking vs not...