Darius M. Moshfeghi

ORCID: 0000-0003-2254-292X
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About
Contact & Profiles
Research Areas
  • Retinal Diseases and Treatments
  • Retinopathy of Prematurity Studies
  • Glaucoma and retinal disorders
  • Retinal and Optic Conditions
  • Retinal Imaging and Analysis
  • Retinal and Macular Surgery
  • Intraocular Surgery and Lenses
  • Neonatal Respiratory Health Research
  • Ocular Oncology and Treatments
  • Neonatal and fetal brain pathology
  • Retinal Development and Disorders
  • Ocular Diseases and Behçet’s Syndrome
  • Ocular Infections and Treatments
  • Ophthalmology and Visual Impairment Studies
  • Preterm Birth and Chorioamnionitis
  • Photodynamic Therapy Research Studies
  • Cardiovascular Conditions and Treatments
  • Child Abuse and Related Trauma
  • Photoacoustic and Ultrasonic Imaging
  • Optical Coherence Tomography Applications
  • Traumatic Ocular and Foreign Body Injuries
  • Nanoplatforms for cancer theranostics
  • Neonatal Health and Biochemistry
  • Drug-Induced Ocular Toxicity
  • Restraint-Related Deaths

Stanford University
2016-2025

Smith-Kettlewell Eye Research Institute
2016-2025

Palo Alto University
2007-2024

Palo Alto Institute
2011-2021

Stanford Medicine
2003-2018

Lucile Packard Children's Hospital
2018

Topcon (Netherlands)
2016

Menlo School
2008-2010

Colégio Brasileiro de Cirurgiões
2009

Cleveland Eye Clinic
2001-2008

Jeffrey S. Heier Eleonora M. Lad Frank G. Holz Philip J. Rosenfeld Robyn H. Guymer and 95 more David S. Boyer F Grossi Caroline R. Baumal Jean‐François Korobelnik Jason S. Slakter Nadia K. Waheed Ravi Metlapally Ian Pearce Nathan Steinle A Francone Allen Hu David R. Lally Pascal Deschatelets Cedric Francois Caleb Bliss Giovanni Staurenghi Jordi Monés Rishi P. Singh Ramiro Ribeiro Charles C. Wykoff Abosede O Cole Adam T. Gerstenblith Ajay Kotagiri Albert O. Edwards Alberto D Zambrano Alexander M. Eaton Alexander Rubowitz Alice T. Lyon Allen Chiang Allen C. Ho Allen Hu Amir Guerami Amr Dessouki André Corrêa Maia de Carvalho Andrés Emanuelli Andrew Chang Andrew N. Antoszyk A Francone Anita Prasad Armin Wolf Arshad M. Khanani Ashkan M. Abbey Asma Moulana Barbara Wihelm Bartosz L. Sikorski Baruch D. Kuppermann Benjamin Wolff Brian Jewart K. Brian Brian T. Chan-Kai Calvin E. Mein Carel B. Hoyng Carl C. Awh Carl Regillio Carlos Zeolite Caroline R. Baumal Catherine Creuzot‐Garcher Catherine Français Maury Charles C. Wykoff Charles K Newell Chirag Jhaveri Chris P. Lohmann Christiana Dinah Colin Ma Courtney Crawford D Wilkin Parke Daniel Lavinsky Daniel B. Roth Dante J. Pieramici Darius M. Moshfeghi Darrin Levin David A. Saperstein David M. Brown David Gaucher David R. Lally David Liao David Warren Brown Debra A. Goldstein Dennis M. Marcus Derek G. Chan Dilsher S. Dhoot Domingo Tacite Dominik Zalewski Edgar M. Espana Eleonora M. Lad Eric H. Souied Eric Suan Eva Eting Federico Furno Sola F. De Bats Francesco Bandello Francisco Gómez‐Ulla François Devin Frank G. Holz Fred K. Chen

10.1016/s0140-6736(23)01520-9 article EN The Lancet 2023-10-01

Laser photocoagulation, which is the standard treatment for retinopathy of prematurity (ROP), can have adverse events. Studies anti-vascular endothelial growth factor injections suggested efficacy in ROP, but few studies directly compared them with laser treatments.To compare intravitreal aflibercept vs photocoagulation infants ROP requiring treatment.This noninferiority, phase 3, 24-week, randomized clinical trial was conducted 27 countries (64 hospital sites) throughout Asia, Europe, and...

10.1001/jama.2022.10564 article EN JAMA 2022-07-26

Retinopathy of prematurity (ROP) is a leading cause blindness in premature and low birth weight infants. Here, the authors examine incidence ROP United States evaluate risk factors associated with development.The National Healthcare Cost Utilization Project Kids' Inpatient Database was queried for all newborns without ROP. Adjusted odds ratios were constructed predictors using multivariate logistic regression modeling.The increased from 14.70% 2000 to 19.88% 2012. Multivariate analysis...

10.3928/23258160-20170630-06 article EN Ophthalmic surgery, lasers & imaging retina 2017-07-01

Optical coherence tomography (OCT) is a powerful biomedical imaging technology that relies on the coherent detection of backscattered light to image tissue morphology in vivo. As consequence, OCT susceptible noise (speckle noise), which imposes significant limitations its diagnostic capabilities. Here we show method based purely manipulation able entirely remove speckle originating from turbid samples without any compromise resolution. We refer this as Speckle-Free (SFOCT). Using SFOCT,...

10.1038/ncomms15845 article EN cc-by Nature Communications 2017-06-20

We developed a photoacoustic ocular imaging device and demonstrated its utility in the deeper layers of eye including retina, choroid, optic nerve. Using safe laser intensity, system was able to visualize blood distribution an enucleated pig's living rabbit. Ultrasound images, which were simultaneously acquired, overlaid on images eye's anatomy. Such may be used future for early detection improved management neovascular diseases, wet age-related macular degeneration proliferative diabetic...

10.1364/ol.35.000270 article EN Optics Letters 2010-01-19

Purpose: To understand factors associated with poor attendance of follow-up appointments for care glaucoma (GL), AMD, and diabetic retinopathy (DR) in a tertiary referral center, to identify strategies improve adherence. Methods: Cross-sectional study 240 adults attending GL, or DR. Cases (N = 102) were patients who missed failed reschedule an appointment within 1 month the recommended date during preceding year. Controls 138) completed assigned follow-up. Data regarding impacting adherence...

10.1167/iovs.15-16444 article EN Investigative Ophthalmology & Visual Science 2015-07-08

To validate a vascular severity score as an appropriate output for artificial intelligence (AI) Software Medical Device (SaMD) retinopathy of prematurity (ROP) through comparison with ordinal disease labels stage and plus assigned by the International Classification Retinopathy Prematurity, Third Edition (ICROP3), committee.Validation study AI-based ROP score.A total 34 experts from ICROP3 committee.Two separate datasets 30 fundus photographs each (0-5) (plus, preplus, neither) were labeled...

10.1016/j.ophtha.2022.02.008 article EN cc-by-nc-nd Ophthalmology 2022-02-12

X-linked cone dystrophy is a type of hereditary retinal degeneration characterized by progressive dysfunction the day vision or photopic (cone) system with preservation night scotopic (rod) function. The disease presents triad photophobia, loss color and reduced central vision. This phenotype distinct from retinitis pigmentosa (RP) in which there are prominent peripheral disturbances. genetically heterogeneous disorder, linkage to loci on Xp11.4–Xp21.1 (COD1, OMIM 304020) Xq27 (COD2,...

10.1093/hmg/11.5.605 article EN Human Molecular Genetics 2002-03-01

10.1007/s00417-008-0819-2 article EN Graefe s Archive for Clinical and Experimental Ophthalmology 2008-04-18

<h3>Aims</h3> To determine the incidence of retinopathy prematurity (ROP) based upon a national database and to identify baseline characteristics, demographic information, comorbidities, surgical interventions. <h3>Methods</h3> The National Inpatient Sample, representative sample all US hospital discharges from 1997 2002, was queried for newborn infants with without ROP. Primary outcome variables included demographics, length stay (LOS), charges. Multivariate logistic regression used predict...

10.1136/bjo.2007.126201 article EN British Journal of Ophthalmology 2008-02-26

10.1007/s00417-007-0559-8 article EN Graefe s Archive for Clinical and Experimental Ophthalmology 2007-03-06

BACKGROUND AND OBJECTIVE: To report the 5-year results of Stanford University Network for Diagnosis Retinopathy Prematurity (SUNDROP) telemedicine initiative. PATIENTS METHODS: Infants requiring retinopathy prematurity (ROP) screening at six neonatal intensive care units from December 1, 2005, to November 30, 2010, were evaluated with remote retinal photography by an ROP specialist. Every infant received outpatient binocular indirect ophthalmoscope examinations until termination criteria...

10.3928/23258160-20140122-01 article EN Ophthalmic surgery, lasers & imaging retina 2014-02-14

BackgroundAge-related macular degeneration (AMD) is a leading cause of visual loss among the elderly. A key cell type involved in AMD, retinal pigment epithelium, expresses G protein–coupled receptor that, response to its ligand, L-DOPA, up-regulates epithelia–derived factor, while down-regulating vascular endothelial growth factor. In this study we investigated potential relationship between L-DOPA and AMD.MethodsWe used retrospective analysis compare incidence AMD patients taking vs not...

10.1016/j.amjmed.2015.10.015 article EN cc-by-nc-nd The American Journal of Medicine 2015-11-04
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