María Ana Martínez-Castellanos

ORCID: 0000-0002-1265-3725
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About
Contact & Profiles
Research Areas
  • Retinopathy of Prematurity Studies
  • Retinal Diseases and Treatments
  • Neonatal Respiratory Health Research
  • Neonatal and fetal brain pathology
  • Retinal and Optic Conditions
  • Retinal Imaging and Analysis
  • Cardiovascular Conditions and Treatments
  • Neonatal and Maternal Infections
  • Retinal and Macular Surgery
  • Intraocular Surgery and Lenses
  • Ocular Diseases and Behçet’s Syndrome
  • Glaucoma and retinal disorders
  • Optical Imaging and Spectroscopy Techniques
  • Neonatal Health and Biochemistry
  • Preterm Birth and Chorioamnionitis
  • Anesthesia and Neurotoxicity Research
  • Retinal Development and Disorders
  • Corneal Surgery and Treatments
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Congenital Heart Disease Studies
  • Diabetes and associated disorders
  • Hemostasis and retained surgical items
  • Corneal surgery and disorders
  • Non-Invasive Vital Sign Monitoring
  • Pediatric Pain Management Techniques

Universidad Nacional Autónoma de México
2012-2025

Asociacion Para Evitar la Ceguera en México Hospital Dr. Luis Sánchez Bulnes
2014-2024

St. Luke's Medical Center
2019

Information Group on Reproductive Choice
2011-2018

Tennessee Retina
2010

In Brief Purpose: To evaluate the role of antiangiogenic therapy with intravitreal bevacizumab for retinopathy prematurity (ROP). Methods: this noncomparative, prospective, interventional case series, was injected into vitreous patients ROP in three different groups: group I, stage IVa or IVb who had no response to conventional treatment; II, threshold were difficult treat because poor visualization retina; and III, high-risk prethreshold ROP. Results: Thirteen (18 eyes; mean age ± SD, 4 3...

10.1097/iae.0b013e318159ec6b article EN Retina 2008-03-01

In Brief Purpose: To evaluate ocular function and systemic development in premature infants treated with intravitreal bevacizumab injections for retinopathy of prematurity over a period 5 years. Methods: A prospective, interventional, noncomparative case study. The primary outcome measure was visual acuity. secondary outcomes were structural assessment, other functional measurements, developmental state. Results: Eighteen eyes 13 consecutive patients divided into 3 groups: Group 1, Stage 4...

10.1097/iae.0b013e318275394a article EN Retina 2012-10-25

Published definitions of plus disease in retinopathy prematurity (ROP) reference arterial tortuosity and venous dilation within the posterior pole based on a standard published photograph. One possible explanation for limited interexpert reliability diagnosis is that experts deviate from definitions.To identify vascular features used by through quantitative image analysis.A computer-based analysis system (Imaging Informatics ROP [i-ROP]) was developed using set 77 digital fundus images,...

10.1001/jamaophthalmol.2016.0611 article EN JAMA Ophthalmology 2016-04-14

To validate a vascular severity score as an appropriate output for artificial intelligence (AI) Software Medical Device (SaMD) retinopathy of prematurity (ROP) through comparison with ordinal disease labels stage and plus assigned by the International Classification Retinopathy Prematurity, Third Edition (ICROP3), committee.Validation study AI-based ROP score.A total 34 experts from ICROP3 committee.Two separate datasets 30 fundus photographs each (0-5) (plus, preplus, neither) were labeled...

10.1016/j.ophtha.2022.02.008 article EN cc-by-nc-nd Ophthalmology 2022-02-12

To evaluate ocular outcome in premature infants treated with intravitreal ranibizumab injections for retinopathy of prematurity (ROP) over a period 3 years.An interventional case series. Premature high-risk prethreshold or threshold ROP plus disease received an off label monotherapy ranibizumab. The primary was treatment success defined as regression neovascularisation (NV) and absence recurrence. secondary outcomes were systemic adverse events visual acuity.Six eyes included the study All...

10.1136/bjophthalmol-2012-302276 article EN British Journal of Ophthalmology 2012-12-08

Although race is a social construct, it associated with variations in skin and retinal pigmentation. Image-based medical artificial intelligence (AI) algorithms that use images of these organs have the potential to learn features self-reported (SRR), which increases risk racially biased performance diagnostic tasks; understanding whether this information can be removed, without affecting AI algorithms, critical reducing racial bias AI.

10.1001/jamaophthalmol.2023.1310 article EN JAMA Ophthalmology 2023-05-04

Abstract We conducted a genome-wide association study (GWAS) in multiethnic cohort of 920 at-risk infants for retinopathy prematurity (ROP), major cause childhood blindness, identifying 1 locus at significance level (p < 5×10 -8 ) and 9 with p -6 ROP ≥ stage 3. The most significant locus, rs2058019, reached within the full = 4.96×10 -9 ); Hispanic European Ancestry driving association. lead single nucleotide polymorphism (SNP) falls an intronic region Glioma-associated oncogene family...

10.1038/s42003-023-05743-9 article EN cc-by Communications Biology 2024-01-17

Retinopathy of prematurity (ROP) is a leading cause childhood blindness. Not only do the epidemiologic determinants and distributions patients with ROP vary worldwide, but clinical differences have also been described. The Third Edition International Classification (ICROP3) acknowledges that aggressive (AROP) can occur in larger preterm infants involve areas more anterior retina, particularly low-resource settings unmonitored oxygen supplementation. As sub-specialty training programs are...

10.3390/jcm12031228 article EN Journal of Clinical Medicine 2023-02-03

This retrospective report describes our 20 months'experience using intravitreal injections of bevacizumab for the treatment several retinal diseases. We describe experience after 1765 in different proliferative retinopathies – retinopathy prematurity, choroidal neovascularization, diabetic retinopathy, among others. believe that findings reported this study move us closer to a better pathologies. However, further studies need be performed order determine safety and long-term efficacy either...

10.1080/08820530701420082 article EN Seminars in Ophthalmology 2007-01-01
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