A5000643157- Ophthalmology and Visual Impairment Studies
- Ophthalmology and Eye Disorders
- Retinopathy of Prematurity Studies
- Intraocular Surgery and Lenses
- Glaucoma and retinal disorders
- Corneal surgery and disorders
- Visual perception and processing mechanisms
- Retinal Diseases and Treatments
- Neonatal Respiratory Health Research
- Ophthalmology and Visual Health Research
- Cerebral Venous Sinus Thrombosis
- Retinal and Optic Conditions
- Neonatal Health and Biochemistry
- Neonatal and fetal brain pathology
- Pituitary Gland Disorders and Treatments
- Vestibular and auditory disorders
- Traumatic Ocular and Foreign Body Injuries
- Nasolacrimal Duct Obstruction Treatments
- Tactile and Sensory Interactions
- Ocular Diseases and Behçet’s Syndrome
- Cancer and Skin Lesions
- Child Abuse and Related Trauma
- Retinal Imaging and Analysis
- Meningioma and schwannoma management
- Healthcare Policy and Management
Johns Hopkins University
2016-2025
Johns Hopkins Medicine
2016-2025
National Eye Institute
2009-2024
University of Baltimore
2008-2023
National Institutes of Health
2022
American Medical Association
2022
American Academy of Ophthalmology
2018-2021
Johns Hopkins Hospital
2002-2021
Ophthalmology Associates (United States)
2021
Hinge Health
2021
To evaluate the effectiveness of treatment amblyopia in children aged 7 to 17 years.At 49 clinical sites, 507 patients with amblyopic eye visual acuity ranging from 20/40 20/400 were provided optimal optical correction and then randomized a group (2-6 hours per day prescribed patching combined near activities for all plus atropine sulfate 12 years) or an (optical alone). Patients whose improved 10 more letters (> =2 lines) by 24 weeks considered responders.In 7- 12-year-olds (n = 404), 53%...
To compare 2 hours vs 6 of daily patching as treatments for moderate amblyopia in children younger than 7 years.In a randomized multicenter (35 sites) clinical trial, 189 years with the range 20/40 to 20/80 were assigned receive either or combined at least 1 hour per day near visual activities during patching.Main Outcome Measure Visual acuity amblyopic eye after 4 months.Visual improved similar amount both groups. The improvement from baseline months averaged 2.40 lines each group (P =.98)....
<h3>Objective</h3> To evaluate the reliability of a new visual acuity testing protocol for children using isolated surrounded HOTV optotypes. <h3>Methods</h3> After initial pilot and modification, was evaluated Baylor-Video Acuity Tester (BVAT) to present At 6 sites, testability in 178 aged 2 7 years subset 88 children. Twenty-eight percent were classified as having amblyopia. <h3>Results</h3> Using modified protocol, ranged from 24% 2-year-olds 96% 5- 7-year-olds. Test-retest high...
The purpose of the study was to examine spherical equivalent refractive errors, especially myopia, at six ages between 3 months and 5 1/2 years post-term in preterm children with birth weights less than 1251 g.A cohort study.There were a total 827 participants multicenter cryotherapy for retinopathy prematurity (ROP). Approximately one third eyes did not develop ROP, whereas two thirds developed mild-to-severe ROP. None underwent cryotherapy.Refractive error measured months, 1 year, term due...
<b>Background:</b> Although peripheral cryotherapy decreases the incidence of unfavorable anatomic outcomes in threshold retinopathy prematurity (ROP), apnea, bradycardia, and lid edema can occur. Argon laser indirect ophthalmoscope photocoagulation has been used as an alternative to cryotherapy, with fewer adverse effects. Retinal lesions placed diode lasers are deeper than similar argon lesions, it is not known whether this difference could influence response ablative therapy....
<h3>Objective</h3> To compare patching and atropine sulfate as treatments for moderate amblyopia in children 18 months after completion of a 6-month randomized trial. <h3>Methods</h3> In randomized, multicenter (47 sites) clinical trial, 419 younger than 7 years with (20/40 to 20/100 the affected eye) were assigned receive either or eye drops 6 months. Between 2 years, treatment was at discretion investigator. <h3>Main Outcome Measure</h3> Visual acuity amblyopic sound years....
We aimed to determine the long-term natural history of low-grade astrocytomas (LGA) in children, with respect pathology, and evaluate influence treatment on survival.A consecutive cohort patients < or =21 years surgically confirmed LGA from 1965 1996 was assembled. All available pathology specimens were reviewed, masked original diagnosis, patient data, neuroimaging.Two hundred seventy-eight children (160 males; mean age 9.1 years; tumor location: 77 cerebrum, 62 cerebellum, 51 hypothalamic,...
<h3>Objective</h3>To describe the structural and visual outcomes at age 6 years of retinal detachment (RD) from retinopathy prematurity (ROP) in Early Treatment for Retinopathy Prematurity (ETROP) study.<h3>Methods</h3>Prospective multicenter nonrandomized series infants with high-risk prethreshold ROP who developed an RD by months corrected treated observation or vitreoretinal surgery.<h3>Results</h3>Of 401 patients, 63 (89 eyes) experienced RD. Follow-up was available 70 eyes (79%) 49...
Intravitreous bevacizumab (0.25 to 0.625 mg) is increasingly used treat type 1 retinopathy of prematurity (ROP), but there remain concerns about systemic toxicity. A much lower dose may be effective while reducing risk.To find a intravitreous that was than previously for severe ROP, in this study, and could tested future larger studies.Between May 2015 September 2016, 61 premature infants with ROP or both eyes were enrolled masked, multicenter, phase de-escalation study. One eye 10 14...