A5062142920- Retinopathy of Prematurity Studies
- Glaucoma and retinal disorders
- Intraocular Surgery and Lenses
- Retinal Diseases and Treatments
- Corneal surgery and disorders
- Neonatal Respiratory Health Research
- Neonatal and fetal brain pathology
- Retinal Imaging and Analysis
- Ophthalmology and Eye Disorders
- Retinal and Optic Conditions
- Ophthalmology and Visual Impairment Studies
- Neonatal Health and Biochemistry
- Retinal and Macular Surgery
- Ocular Diseases and Behçet’s Syndrome
- Ocular Infections and Treatments
- Traumatic Ocular and Foreign Body Injuries
- Ophthalmology and Visual Health Research
- Cerebral Venous Sinus Thrombosis
- Optical Imaging and Spectroscopy Techniques
- Optical Coherence Tomography Applications
- Ocular Surface and Contact Lens
- Corneal Surgery and Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Retinal Development and Disorders
- Cardiovascular Conditions and Treatments
Duke Medical Center
2016-2025
Duke University
2015-2024
Duke University Hospital
1999-2024
Duke Regional Hospital
2018-2022
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2021
Research Network (United States)
2021
Triangle
2020
National Center on Birth Defects and Developmental Disabilities
2020
W.K. Kellogg Foundation
2020
University of Michigan
2020
Glaucoma-related adverse events constitute major sight-threatening complications of cataract removal in infancy, yet their relationship to aphakia vs primary intraocular lens (IOL) implantation remains unsettled.To identify and characterize cases glaucoma glaucoma-related (glaucoma + suspect) among children the Infant Aphakia Treatment Study by age 5 years.A multicenter randomized clinical trial 114 infants with unilateral congenital referral centers who were between ages 1 6 months at...
To describe age-related considerations and methods to improve hand-held spectral domain optical coherence tomography (HH-SD OCT) imaging of eyes neonates, infants, children.
The Infant Aphakia Treatment Study recommended primary intraocular lens (IOL) implantation be reserved for infants with parents unable to manage contact lenses. best baseline predictor of a good visual outcome was private health insurance. IOL associated more adverse events, but lower direct costs parents.
<h3>Objectives</h3> To evaluate the spectrum of foveal architecture in pediatric albinism and to assess utility spectral-domain optical coherence tomography (OCT) ocular imaging children with nystagmus. <h3>Methods</h3> Spectral-domain OCT was performed on study subjects 3 groups: (OA) or suspected OA hypoplasia, nystagmus, without iris transillumination; a subject oculocutaneous Hermansky-Pudlak syndrome; control subjects. Dense volumetric scans each fovea were captured using standard...
Intravitreous bevacizumab (0.25 to 0.625 mg) is increasingly used treat type 1 retinopathy of prematurity (ROP), but there remain concerns about systemic toxicity. A much lower dose may be effective while reducing risk.To find a intravitreous that was than previously for severe ROP, in this study, and could tested future larger studies.Between May 2015 September 2016, 61 premature infants with ROP or both eyes were enrolled masked, multicenter, phase de-escalation study. One eye 10 14...
To investigate whether the severity of cystoid macular edema (CME) in neonates who were 31 to 36 weeks' postmenstrual age, as viewed by spectral-domain optical coherence tomography (SD-OCT)imaging, predicts retinopathy prematurity(ROP) or is related systemic health.Of 62 prematurely born a prospective institutional review board-approved study, 42 met following inclusion criteria: at least 1 SD-OCT imaging session prior 37 age and ROP laser treatment, if treatment was performed,and an...
Objectives: To report the incidence of glaucoma and suspects in IATS, to evaluate risk factors for development a glaucoma-related adverse event patients IATS first year follow-up.Methods: A total 114 infants between 1 6 months age with unilateral congenital cataract were assigned undergo surgery either or without an intraocular lens implant.Standardized definitions suspect created used IATS.Results: Of these patients, 10 (9%) developed 4 (4%) had suspect, 14 (12%) treated eye through...
To determine whether earlier treatment of high-risk, prethreshold retinopathy prematurity (ROP) improves retinal structural outcome at 2 years age.Infants with bilateral high-risk ROP had one eye randomly assigned to peripheral ablation. The fellow was managed conventionally, and either treated threshold or observed if never reached. In patients asymmetrical disease, the randomised conventional management. At age, children were examined comprehensively by certified ophthalmologists outcomes...
To compare vitreoretinal pathology imaged with portable handheld spectral-domain optical coherence tomography (SD-OCT) to conventional indirect ophthalmoscopic examination in neonates undergoing screening for retinopathy of prematurity.Spectral-domain images were collected from 76 eyes 38 during 118 routine prematurity examinations. Imaging sessions the Neonatal Intensive Care Unit performed immediately after subjects underwent a standard ophthalmic by pediatric ophthalmologist. Masked...
Self-poisoning-Kessel MEDITALIJOURNAL cases of self-poisoning coming to hospital and not just with those somehow selected for psychiatric investigation.Those no illness tended be younger ; organic illnesses were generally old.Apart from this the relation between diagnosis age was close.The principal related index endanger- ing life (Table VIII).The acts patients a formal (excluding character disorder) more life-endangering than personality abnor- mality or without illness.Yet majority even...
<h3>BACKGROUND AND PURPOSE:</h3> IIH is a disorder associated with increased intracranial pressure no clinical, laboratory, or radiologic evidence of an space-occupying lesion. The aim this study was to establish ONSD standards healthy pediatric subjects and compare the normal measurements those patients IIH. <h3>MATERIALS METHODS:</h3> One hundred fifteen MR imaging studies children 4 months 17 years age were blinded reviewed by neuroradiologist. A total 230 optic nerves measured....
To determine the reproducibility of spectral-domain optical coherence tomography (OCT) measurements peripapillary retinal nerve fiber layer (RNFL) and macular thickness central 20-degree area posterior pole in adult pediatric glaucoma normal subjects.Prospective.Normal, suspect eyes subjects were recruited. Spectralis OCT scans obtained 3 times on same day (intravisit) 4 weeks later (intervisit). Six individual sectors, average RNFL, using an 8×8 mm grid centered foveal pit measured for all...