Michael J. Lang

ORCID: 0000-0002-4755-0830
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About
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Research Areas
  • Intracranial Aneurysms: Treatment and Complications
  • Cerebrovascular and Carotid Artery Diseases
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Neurosurgical Procedures and Complications
  • Vascular Malformations Diagnosis and Treatment
  • Acute Ischemic Stroke Management
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Stroke Rehabilitation and Recovery
  • Venous Thromboembolism Diagnosis and Management
  • Spinal Hematomas and Complications
  • Head and Neck Surgical Oncology
  • Trigeminal Neuralgia and Treatments
  • Blood Coagulation and Thrombosis Mechanisms
  • Retinal and Optic Conditions
  • Cerebral Venous Sinus Thrombosis
  • Congenital heart defects research
  • Congenital Heart Disease Studies
  • Cardiovascular Conditions and Treatments

University of Pittsburgh Medical Center
2020-2024

Neurological Surgery
2020-2024

University of Pittsburgh
2022-2024

Beaumont Hospital, Royal Oak
1991

INTRODUCTION: Multiple preferences exist in terms of embolic materials middle meningeal artery embolization (MMAE) for chronic subdural hematoma (cSDH) with limited comparative literature data. METHODS: Consecutive patients undergoing MMAE cSDH at 14 North-American centers (2018-2023) were included. Patients classified into 3 groups a) particles, b) Onyx, c) n-BCA. The endpoints unplanned rescue surgery and radiographic success (=50% reduction thickness last imaging "minimum 2-weeks")....

10.1227/neu.0000000000003360_1141 article EN Neurosurgery 2025-03-14

Ruptured blister, dissecting, and iatrogenic pseudoaneurysms are rare pathologies that pose significant challenges from a treatment standpoint. Endovascular via flow diversion represents an increasingly popular option; however, drawbacks include the requirement for dual antiplatelet therapy potential thromboembolic complications, particularly acute complications in ruptured setting. The Pipeline Flex embolization device with Shield Technology (PED-Shield) offers reduced material...

10.3171/2023.2.focus233 article EN Neurosurgical FOCUS 2023-05-01

BACKGROUND AND OBJECTIVES: Multiple preferences exist for embolic materials selection in middle meningeal artery embolization (MMAE) chronic subdural hematoma with limited comparative literature data. Herein, we compare different materials. METHODS: Consecutive patients undergoing MMAE at 14 North-American centers (2018-2023) were classified into 3 groups: (a) particles, (b) Onyx, (c) n-butyl cyanoacrylate (n-BCA). The end points unplanned rescue surgery, radiographic success (≥50% reduction...

10.1227/neu.0000000000003218 article EN Neurosurgery 2024-10-17

Background We report the largest multicenter experience to date of utilizing Comaneci device for endovascular treatment refractory intracranial vasospasm. Methods Consecutive patients undergoing mechanical dilatation vasospasm were extracted from prospectively maintained registries in 11 North American centers (2020–2022). Intra-arterial vasodilators (IAV) allowed, with utilized after absence vessel dilation post-infusion. Pre- and post-vasospasm scores recorded each segment, primary...

10.1136/jnis-2022-019272 article EN Journal of NeuroInterventional Surgery 2022-08-24

Abstract Introduction United States stroke systems are increasingly transitioning from alteplase (TPA) to tenecteplase (TNK). Real-world data on the safety and effectiveness of replacing TPA with TNK before large vessel occlusion (LVO) endovascular treatment (EVT) lacking. Methods Four Pennsylvania transitioned during study period 01/2020–06/2023. LVO patients who received intravenous thrombolysis or EVT were reviewed. Multivariate logistic analysis was conducted adjusting for age, sex,...

10.1007/s00415-024-12530-x article EN cc-by Journal of Neurology 2024-07-03

Abstract BACKGROUND While multiple new larger-bore aspiration catheters have been introduced for stroke thrombectomy, sizeable cohort outcome studies are lacking along with meaningful comparative to evaluate whether they represent a clinically relevant improvement compared predecessors. OBJECTIVE To angiographic and clinical outcomes between an 071 068 catheter. METHODS The authors reviewed institutional thrombectomy database extracting the first 150 consecutive cases utilizing React 71...

10.1093/neuros/nyaa498 article EN Neurosurgery 2020-11-06

OBJECTIVE Acute basilar artery occlusion (BAO) harbors a more guarded prognosis after thrombectomy compared with anterior circulation large-vessel occlusion. Whether this is function of greater proportion atherosclerotic/intrinsic lesions not well studied. The authors aimed to elucidate the prevalence and predictors intracranial intrinsic atherosclerotic disease in patients acute BAO compare angiographic clinical outcomes between secondary embolic versus disease. METHODS A prospectively...

10.3171/2021.4.focus2189 article EN Neurosurgical FOCUS 2021-07-01

Persistent truncus arteriosus (TA) is an uncommon congenital cardiovascular malformation, which comprises between 0.4% and 4% of all heart defects. Occurrence TA in siblings has been reported infrequently. Twins concordant for isolated appear to have only once previously. In this paper, we describe dizygotic twin females who were TA.

10.1111/j.1399-0004.1991.tb02989.x article EN Clinical Genetics 1991-01-01

Middle meningeal artery embolization (MMAE) has revolutionized the armamentarium for chronic subdural hematoma (CSDH) treatment. Technical and angiographic benchmarks to guide procedural clinical success are less well established.

10.1016/j.wneu.2024.10.013 article EN cc-by-nc World Neurosurgery 2024-11-01

BACKGROUND AND OBJECTIVES: The benefit of middle meningeal artery embolization (MMAE) in the treatment chronic subdural hematoma (CSDH) has been recently demonstrated a series clinical trials. Whether MMAE benefits “trial-ineligible” patients remains elusive. We thus sought to explore potential neurologically stable (modified Rankin Scale ≤3) with CSDHs because large size: Thickness >15 mm and/or midline shift ≥5 mm. METHODS: A prospectively maintained database was reviewed identify...

10.1227/neu.0000000000003136 article EN Neurosurgery 2024-08-08
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