A5083044064- Nanoparticles: synthesis and applications
- Metal complexes synthesis and properties
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Metal-Catalyzed Oxygenation Mechanisms
- Graphene and Nanomaterials Applications
- Phenothiazines and Benzothiazines Synthesis and Activities
- Computational Drug Discovery Methods
- Plant Pathogens and Fungal Diseases
- Microbial Natural Products and Biosynthesis
- Ethnobotanical and Medicinal Plants Studies
- Essential Oils and Antimicrobial Activity
- Antimicrobial Resistance in Staphylococcus
- Synthesis and biological activity
- Molecular Sensors and Ion Detection
- Antibiotic Resistance in Bacteria
- Diverse Scientific Research Studies
- Metal-Organic Frameworks: Synthesis and Applications
- Nanoparticle-Based Drug Delivery
- Microbial Metabolism and Applications
- Magnetism in coordination complexes
- Piperaceae Chemical and Biological Studies
- Probiotics and Fermented Foods
- Crystallography and molecular interactions
- Bacteriophages and microbial interactions
Arya Vaidya Sala
2023-2025
Central Institute of Brackishwater Aquaculture
2022-2024
Anna University, Chennai
2018-2023
Orthopaedic Research Group
2021-2022
Bharathidasan University
2020-2021
Sri Ramakrishna Institute of Paramedical Sciences
2016-2018
Pharmaceutical Biotechnology (Czechia)
2018
Tamil Nadu Dr. M.G.R. Medical University
2016
This is the first report of silver nanoparticles (AgNPs) synthesis utilizing pitcher secretion from an insectivorous plant, specifically Nepenthes ventrata, through a microwave assisted green approach. The successful formation AgNPs was validated comprehensive set analyses, including UV–Vis spectroscopy, Fourier-transform infrared transmission electron microscopy, DLS analysis and Zeta potential measurements. In addition gas chromatography-high-resolution mass spectrometry liquid analyses...
Melanin is a complex biological pigment found in various living organisms. The primary function of melanin to absorb and dissipate ultraviolet (UV) radiation, protecting against the harmful effects sunlight. To Present computational study electronic structures its binding propensities with skin cancer-related proteins (1P7K, 2VCJ, 5OTE). We used molecular docking, free energy analysis, MD simulations, DFT explore. Melanin's optimized geometry, quantum descriptors, electrostatic potential...
Abstract Currently, available treatment for osteosarcoma is combinational chemotherapy of doxorubicin, cisplatin, and methotrexate before after surgery with overall 5‐year survival rate less than 40%. The present study was aimed to assess the anticancer effects a phytochemical named β‐caryophyllene (BCP) in treating osteosarcoma. We assessed effect on oxidative stress, proliferation, apoptosis, inflammation human bone cancer cells MG‐63. Our results showed that BCP induced reactive oxygen...
In pursuit of the significant contribution copper ion in different biological processes, this research work describes synthesis, X‐ray structure, Hirshfeld surface analysis, oxidative dimerization 2‐aminophenol and antibacterial activity a newly designed (II)‐Schiff base complex, [Cu( L ) 2 ] (1), [Schiff (H = 2‐(2‐methoxybenzylideneamino)phenol]. X ‐ ray structural analysis 1 reveals that Cu (II) complex crystallizes cubic crystal system with I a‐3d space group. The centre adopts an...
The manuscript reports the green-chemical synthesis of a new diindole-substituted benzimidazole compound, B1 through straightforward route in coupling between indolyl-3-carboxaldehyde and o-phenylenediamine water medium under aerobic condition at 75 ºC. single crystal X-ray structural analysis suggests that disubstituted compound crystallizes monoclinic system indole groups exist perpendicular fashion with respect to moiety. SARS-CoV-2 screening activity has been studied against 1 × 10e4...
Phenazine scaffolds are the versatile secondary metabolites of bacterial origin. It functions in biological control plant pathogens and contributes to producing strains ecological fitness pathogenicity. In light excellent therapeutic properties phenazine, we have synthesized a hydrated 2,3-diaminophenazinium chloride (DAPH
Background: Medicinal plants present a wide range of potentially phytochemical compounds that contain many useful properties including anticancer, enzyme inhibition, anti-inflammatory, antifungal, antibacterial, immunomodulatory, antioxidant, and antiallergic activities. Phyllanthus niruri capsules are extensively recommended to improve the function diseased liver. Its leaves root whole plant used as an herbal complement.Aim: The study was aimed focus on in vitro immunomodulatory activity,...
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Green nanotechnology has recently had a significant influence on advances in biological applications. The surface manipulation of iron oxide NPs by zinc is increasing attention for biomedical research. Therefore, this work focused the phytochemicals creeper Blepharis maderaspantensis (BM) water extract synthesizing and oxide/zinc nanocomposite. UV spectrum analysis showed wavelength redshift from 294 to 302 nm oxide/ZnO nanocomposite, polydispersity index revealed that perfect preparations...
Introduction Microorganisms originating from the marine environment, such as bacteria, fungi, and algae, are deliberately employed in production of nanoparticles on account wide array bioactive compounds they produce. Methods Cell-free aqueous extracts Bacillus subtilis (CBPPR1) were used to synthesise AuNPs (CBPPR1AuNPs) AgNPs (CBPPR1AgNPs). Zetasizer Nano ZS (Malvern Instruments) zeta size potential, field emission transmission scanning electron microscopy (FE-SEM HR-TEM), UV-visible...
Background: Fungi produce a wide range of secondary metabolites with bactericidal or bacteriostatic properties. In search novel antibacterial compounds recently, many fungi marine and plant origin have been studied for their antimicrobial Aims: This work aimed to study bio-prospect endophytic Methods: Intensive microbiological methods were followed isolation, differential growth, qualitative screening enzyme production. The isolates characterised identified based on morpho-taxonomy, 18S rRNA...
Background: Marine sediment bacteria have been generating considerable attention lately due to their potential as valuable reservoirs of novel antimicrobial agents. Aim: In vitro and in silico antibacterial activities compounds isolated from the marine bacterium Enterococcus Lactis (S-2). Methods: Coastal samples were collected Rameswaram, Ramnathapuram District, Tamil Nadu, India. Bacteria using crowded plate method, phenotypic genotypic characteristics studied. Purified cultured large...
The beneficial effects of statins, other than their hypocholesterolemia role, have been well documented, however, use as an adjuvant drug with antiseizure drugs, in the treatment epilepsy is poorly understood.This study aimed to investigate symbiotic effect ATOR along either lacosamide (LACO) or levetiracetam (LEVE) on experimentally induced (Maximal electro-shock-MES pentylenetetrazol- PTZ) mice models.Conventional elevated-maze (EPM) and rotarod methods were performed observe behavioral...
This study deals with the synthesis, structural characterization, proto-coupled-electron-transfer, bactericidal and cytotoxicity of a hemilabile water-soluble 2-(2′-pyridyl)-imidazole nickel( ii ) complex.
The marine ecosystem contains many microbial species that produce unique, biologically active secondary metabolites with complex chemical structures. We aimed to isolate and identify bioactive compounds antimicrobial properties produced by a facultative anaerobic strain of Bacillus subtilis (AU-RM-1), isolated from sediment.We optimized the AU-RM-1 growth conditions, analyzed its kinetics phenotypic genotypic characteristics. Extracts were studied for activity against three clinically...
A photo‐switchable ionophore, (E)‐4‐([2‐hydroxy‐3‐methoxybenzylidene]amino)‐1,5‐dimethyl‐2‐phenyl‐1,2‐dihydro‐3H‐pyrazol‐3‐one ( S1 ), was rationally designed and developed for the visible light‐triggered selective efficient transport of Al (III) ions. The non‐fluorescent probe distinctly manifests its green light at 518 nm in presence ion upon irradiation 405 showed a turned‐off emission with EDTA ethanol. binding mode structural perspective were assessed through X‐ray crystallography,...
Background: Resistant growth is recognized as a significant public health hazard to human worldwide among the most critical bacterial diseases. The evolving multidrug-resistant species are now commonly found in community settings, not just hospital area, which means that antibiotic bacteria reservoirs beyond hospital. Aim: In this study, we synthesized novel N4, N4'-dibutyl-3,3'-dinitro-[1,1'-biphenyl]-4,4'-diamine from 3,3'-dinitro-[1,1'-biphenyl]-4,4'-diamine and evaluation of its...