- Lung Cancer Diagnosis and Treatment
- Ocular Oncology and Treatments
- Pulmonary Hypertension Research and Treatments
- Cellular Mechanics and Interactions
- Tracheal and airway disorders
- Shoulder Injury and Treatment
- COVID-19 and healthcare impacts
- Immunotherapy and Immune Responses
- Head and Neck Cancer Studies
- Management of metastatic bone disease
- 3D Printing in Biomedical Research
- Medical Imaging and Pathology Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Cancer Diagnosis and Treatment
- Venous Thromboembolism Diagnosis and Management
- Spinal Fractures and Fixation Techniques
- Glioma Diagnosis and Treatment
- Hip and Femur Fractures
- Veterinary Oncology Research
- Dysphagia Assessment and Management
- Single-cell and spatial transcriptomics
- Advanced Fluorescence Microscopy Techniques
- Pelvic and Acetabular Injuries
- Meningioma and schwannoma management
- Bone health and treatments
University of South Florida
2022-2024
University of Florida
2024
Johns Hopkins University
2024
Stony Brook University
2024
Lehigh Valley Health Network
2024
Children's Hospital of Philadelphia
2024
Moffitt Cancer Center
2023
Bioengineering Center
2023
University of Illinois Urbana-Champaign
2020-2022
Aim: Conventional techniques to share and archive spinal imaging data raise issues with trust security, novel approaches being more greatly considered. Ethereum smart contracts present one such approach. is an open-source platform that allows for the use of contracts. Smart are packages code self-executing reside in state, defining conditions programmed transactions. Though powerful, limited attempts have been made showcase clinical utility technologies, especially pre- post-operative...
Hypoxia has established associations with aggressive tumor phenotypes in many cancers. However, it is not currently understood whether hypoxia levels map to distinct immune infiltrates cutaneous melanoma, potentially unveiling novel therapeutic targets. To this end, we leveraged a previously identified seven-gene signature grade of 460 melanomas obtained from the Broad Institute GDAC Firehose portal. CIBERSORTx (https://cibersortx.stanford.edu/) was employed calculate relative abundance 22...
American football is the most popular sport in United States, with over 5.6 million people >6 years old playing sport. Fractures athletes are significant, as they compromise an athlete's performance and can also lead to prolonged recovery periods, affecting team dynamics player careers. Analyzing these injuries critical evaluate preventive measures tailor rehabilitation strategies ensure well-being sustained peak of on off field.
Abstract Purpose: Intracranial neoplasms are the leading cause of cancer death among men under 40 years old. A major part standard care is excision tumor, but there a lack robust large-patient studies outcomes for these patients. Methods: The Nationwide Inpatient Sample was queried from 2018 to 2020 identify patients with an intracranial neoplasm. Multivariable linear regression patient- and hospital-level characteristics as covariates used factors associated long hospital stays. Results:...
Abstract Purpose: Excision of intracranial neoplasms is a life-saving procedure. However, there not much research that has demonstrated how demographic variables interact with patient’s access to healthcare for neoplasms. Methods: The Nationwide Inpatient Sample was queried from 2018 2020 identify patients an neoplasm. Multivariable logistic regression patient- and hospital-level characteristics as covariates used factors associated receiving tumor excision. Results: From 2020, were 97,795...
Introduction: Proximal humerus fractures (PHFs) are one of the most common among patients aged 65 years and older, commonly due to low-energy mechanisms. It is essential identify drivers increased healthcare utilization in geriatric PHF bring awareness any disparities care. Here, we factors associated with likelihood inpatient admission prolonged hospital stay older who sustain falls. Methods: A national database was used suffered proximal humeral a fall. Patient were analyzed for...
Thumb carpometacarpal arthritis is common with aging, more in women than men, and usually occurs after age 40. If a patient fails conservative treatments such as splinting, medications, corticosteroid injections, then surgical intervention may be appropriate. Currently, there no consensus on the best treatment. By limiting metacarpal subsidence, ligament suspensionplasty suture tape augmentation offers great pain relief, excellent functional outcomes, limited postoperative immobilization....
ABSTRACT Introduction: Atlas and axis fractures are the most severe cervical which may result in complete paralysis or death. The purpose of current study is to identify disparities regarding length stay (LOS), mortality, demographic factors patients with serious spine utilizing a nationally representative database. Materials Methods: Nationwide Emergency Department Sample was utilized provide sample for primary diagnosis C1 C2 fracture presenting emergency departments years from October...
Abstract Purpose: Uveal melanoma has a high tendency to metastasize. Due its rarity, there not been large population studies that have demonstrated the effect of demographic variables on patient’s risk metastases. Methods: The Nationwide Emergency Department Sample was queried from last quarter 2015 2019 identify patients with diagnosis uveal melanoma. Multivariable logistic regression, patient- and hospital-level characteristics as covariates, used factors associated higher chance...
Abstract Purpose: Uveal melanoma is a rare ocular malignancy that has not been well characterized at large scale. Specifically, uveal diagnosis and outcomes in the emergency department (ED) characterized. Methods: The Nationwide Emergency Department Sample was queried from last quarter of 2015 to 2019 identify patients with primary melanoma. Multivariable logistic regression, patient- hospital-level characteristics as covariates, used factors associated increased risk inpatient admission....
Abstract Purpose: A considerable amount of uveal melanoma patients present to the emergency department (ED) for a complication related their primary tumor. However, there is not much research into reasons these ED and outcomes. Methods: The Nationwide Emergency Department Sample was queried from last quarter 2015 2019 identify with diagnosis melanoma. Multivariable logistic regression, patient- hospital-level characteristics as covariates, used factors associated increased risk in-hospital...
Purpose There has been abundant research published regarding the impact of COVID-19 on orthopaedic surgical patients which have varying degrees clinical practice. Thus, purpose this study was to examine most influential articles relating and undergoing procedures. Though global pandemic is over, it beneficial understand how resilience healthcare system adapted guide policy development improve patient care amidst a worldwide time crisis. Methods The Clarivate Web Science Core Collection...
Since the early 2000s, robotic-assisted surgery has evolved in field of thoracic surgery, and pulmonary lobectomy (RAPL) become a popular safe treatment method for patients seeking removal lung cancer. The purpose current study was to identify examine top-50 most influential articles RAPL from 2003 2021 using bibliometric analysis. Clarivate Web Science Core Collection systematically searched gather data on RAPL. Descriptive information each article collected reported descriptive statistics....
Background: The blood urea nitrogen to serum albumin ratio (BAR) is an emerging prognostic parameter of interest. utility BAR as a factor has not been analyzed in lung cancer patients undergoing pulmonary lobectomy. We evaluated the ability High predict worse outcomes after robotic-assisted lobectomy (RAPL) for cancer. Methods: retrospectively 400 who underwent RAPL from September 2010 March 2022 by one surgeon. Patients were stratified Low (<6.25 mg/g) and (≥6.25 mg/g). Patients’...
Objective: The significant metastatic potential of uveal melanoma (UVM) lends to high mortality. Even with successful local tumor treatment, many patients will develop disease. present study aims elucidate the relationship between tumor-infiltrating immune cell (TIIC) diversity and survival identify therapeutic targets improve UVM prognosis. Methods: Bulk deconvolution was used determine relative proportions 22 hematopoietic TIIC from 80 samples. Cytolytic activity (CYT) determined,...
Abstract Fluorescent microscopy employs monochromatic light which can affect the cells being observed. We reported earlier that fibroblasts relax their contractile force in response to green of typical intensity. Here we show such effects are independent extracellular matrix and type cell. In addition, establish a threshold invokes minimal effect on cells. cultured soft 2D elastic hydrogels embedded with fluorescent beads trace substrate deformation. The move towards cell center when...