A5034539727- Cellular Mechanics and Interactions
- 3D Printing in Biomedical Research
- Cancer Cells and Metastasis
- Cardiac electrophysiology and arrhythmias
- Advanced Fluorescence Microscopy Techniques
- Hippo pathway signaling and YAP/TAZ
- Neuroscience and Neural Engineering
- Hybrid Renewable Energy Systems
- Collagen: Extraction and Characterization
- Wnt/β-catenin signaling in development and cancer
- Microfluidic and Bio-sensing Technologies
- Cancer Research and Treatments
- Planarian Biology and Electrostimulation
- Spectroscopy Techniques in Biomedical and Chemical Research
- Orthopaedic implants and arthroplasty
- Bone fractures and treatments
- Wind Energy Research and Development
- Bone Tissue Engineering Materials
- bioluminescence and chemiluminescence research
- Force Microscopy Techniques and Applications
- Wind Turbine Control Systems
University of Illinois Urbana-Champaign
2020-2025
Bangladesh University of Engineering and Technology
2017
Colorectal cancer metastasis is governed by a variety of chemical and mechanical signaling that are largely influenced cancer-associated fibroblasts (CAFs) in the tumor microenvironment. Here, we deconvolute from case colon cell line HCT-116 CAFs. We examined three chemoattractants (CXCL12, TGF-β, activin A) which allegedly secreted CAFs induce migration. None tested resulted enhanced migration 2D transwell assay, at low density. Similarly, CAF-conditioned media also did not lead to...
A nano-resolution PDMS sensor simultaneously measures cell force and matrix stiffening dynamics in 3D.
Abstract Cells in vivo generate mechanical forces (traction) on surrounding 3D extra cellular matrix (ECM) and cells. Such traction biochemical cues may remodel the matrix, e.g. increase stiffness, which turn influences cell functions forces. This dynamic reciprocity mediates development tumorigenesis. Currently, there is no method available to directly quantify single remodeling 3D. Here, we introduce a fulfil this long-standing need. We developed high-resolution microfabricated sensor...
Abstract Fluorescent microscopy employs monochromatic light which can affect the cells being observed. We reported earlier that fibroblasts relax their contractile force in response to green of typical intensity. Here we show such effects are independent extracellular matrix and type cell. In addition, establish a threshold invokes minimal effect on cells. cultured soft 2D elastic hydrogels embedded with fluorescent beads trace substrate deformation. The move towards cell center when...
In this work, a theoretical analysis has been carried out to analyze the prospect of Wind Pumping System (WPS) for using in coastal areas Bangladesh. speed data three Bangladesh-Kutubdia, Patenga and Sathkhira analyzed an optimal wind turbine viable range designed simulation software Q-blade. The simulated is then coupled with rotodynamic pump. output studied.
Cells in functional tissues execute various collective activities to achieve diverse ordered processes including wound healing, organogenesis and tumor formation. How a group of individually operating cells initiate such complex is still not clear. Here, we report that 3D Extra Cellular Matrix (ECM) behavior by forming cell-ECM network when the are within critical distance between each other. Beyond distance, does emerge. We studied compaction free-floating (FF) collagen gels with embedded...