- Plant Stress Responses and Tolerance
- Retinal Development and Disorders
- Plant responses to water stress
- Retinal Diseases and Treatments
- Photosynthetic Processes and Mechanisms
- Botulinum Toxin and Related Neurological Disorders
- Connexins and lens biology
- GABA and Rice Research
- Legume Nitrogen Fixing Symbiosis
- Ocular Disorders and Treatments
- Rice Cultivation and Yield Improvement
- Neurological disorders and treatments
- Plant tissue culture and regeneration
- Cell Adhesion Molecules Research
- Plant nutrient uptake and metabolism
- Nutritional Studies and Diet
- Plant Molecular Biology Research
- RNA regulation and disease
- Soybean genetics and cultivation
- Plant Genetic and Mutation Studies
- Fatty Acid Research and Health
- Nematode management and characterization studies
- melanin and skin pigmentation
- Glaucoma and retinal disorders
- Genetic Mapping and Diversity in Plants and Animals
Jawaharlal Nehru University
2014-2024
Nalanda Medical College and Hospital
2022
COMSATS University Islamabad
2020
Patna Medical College and Hospital
2018
Indian Institute of Technology Delhi
2016
Jamia Millia Islamia
2011
Walkergate Park Hospital
2009
Institute of Biomedical and Genetic Engineering
1998-2006
Crop plants face a multitude of diverse abiotic and biotic stresses in the farmers' fields. Although there now exists considerable knowledge underlying mechanisms response to individual stresses, crosstalk between pathways various remains enigmatic. Here, we investigated if cytotoxic metabolite methylglyoxal (MG), excess which is generated as common consequence many may serve key molecule linking responses stresses. For this, transgenic rice overexpressing entire two-step glyoxalase pathway...
Edaphic factors such as salinity, sodicity, and drought adversely affect crop productivity, either alone or in combination. Despite soil sodicity being reported an increasing problem worldwide, limited efforts have been made to address this issue. In the present study, we aimed generate rice with tolerance conjunction salinity drought. Using a fusion gene from E. coli coding for trehalose-6-phosphate synthase/phosphatase (TPSP) under control of ABA-inducible promoter, generated marker-free,...
Abstract Abiotic stresses such as heat, drought and submergence are major threats to global food security. Despite simultaneous or sequential occurrence of these being recurrent under field conditions, crop response stress combinations is poorly understood. Rice a staple for the majority human beings. Exploitation existing genetic diversity in rice combined and/or useful approach developing climate‐resilient cultivars. We phenotyped ~400 accessions high temperature, drought, their...
Cytoskeleton plays a vital role in stress tolerance; however, involvement of intermediate filaments (IFs) such response remains elusive crop plants. This study provides clear evidence about the unique IFs cellular protection against abiotic rice. Transcript abundance Oryza sativa filament (OsIF) encoding gene showed 2-10 fold up-regulation under different stress. Overexpression OsIF transgenic rice enhanced tolerance to salinity and heat stress, while its knock-down (KD) rendered plants more...
Abstract High salinity is one of the major problems in crop productivity, affecting seed germination as well yield. In order to enhance tolerance crops towards salinity, it essential understand underlying physiological and molecular mechanisms. this endeavor, study contrasting genotypes same species differing their response stress can be very useful. present study, we have investigated temporal differences morphological, proteome profiles two rice basis salt tolerance. When compared IR64...
<h3>Objectives</h3> To describe the phenotype of Leber congenital amaurosis (LCA) in 26probands with mutations aryl hydrocarbon receptor interacting protein-like1 protein (<i>AIPL1</i>) and compare it phenotypesof other LCA-related genes. electroretinogram (ERG) heterozygotecarriers. <h3>Methods</h3> Patients with<i>AIPL1</i>-related LCA were identifiedin a cohort 303 patients by polymerase chain reaction single-strandconfirmational polymorphism mutation screening and/or direct sequencing....
Saffron is one of the most expensive spices world. Since this spice triploid and meiosis unusual, it cannot reproduce sexually like other plants; rather, propagated vegetatively via an underground corm, which can withstand a long dry dormant period before sprouting. Thus, corms are indispensable to saffron propagation. To identify analyse signature metabolites associated with 'dormancy-sprouting' process, non-targeted GC-MS was performed at different stages corm development. Comparative...
Abstract With the growing resistance of parasites to most currently available anthelmintics and increasing concerns about anthelmintic residues in animal products environment, there is a heightened interest exploring plant-based alternatives. This study aims evaluate properties Leucaena leucocephala var. tarramba leaf extracts against gastrointestinal ruminants, examining their effects on internal vitro vivo. For analysis, eggs isolated from fresh fecal samples worm-infected goats were...
Objective: To assess the validity and reliability of a Numeric Rating Scale (NRS) for measurement spasticity in multiple sclerosis. Design: Longitudinal study with comparators over two clinic visits. Setting: Rehabilitation Centre
Abstract Intensive breeding programs have increased rice yields, strongly contributing to increasing global food security during the post‐green revolution period. However, productivity has reached a yield barrier where further improvement is restricted by inadequate information on association of components, and morphological physiological traits with yield. We conducted field experiment evaluate (i) contribution (ii) quantify trade‐off effect between components in rice, using mini‐core...
Mutations in the rhodopsin gene are reported to be responsible for approximately 25% of all cases autosomal dominant Retinitis pigmentosa (adRP). Affected individuals from a large family with an unusually severe form adRP were screened mutations gene. Direct sequencing exon 5 revealed TAA GAA transversion at nucleotide 5276 / codon 349, which was confirmed by Dde 1 restriction digest analysis. This change would replace normal termination glutamic acid residue (Ter-349-Glu, or X349E). The...