- Glioma Diagnosis and Treatment
- Phytochemicals and Medicinal Plants
- Essential Oils and Antimicrobial Activity
- Cancer Cells and Metastasis
- CAR-T cell therapy research
- Angiogenesis and VEGF in Cancer
- Medicinal Plants and Neuroprotection
- Virus-based gene therapy research
- Bone health and treatments
- Cardiovascular Function and Risk Factors
- Respiratory and Cough-Related Research
- Food Science and Nutritional Studies
- Boron Compounds in Chemistry
- Radiopharmaceutical Chemistry and Applications
- Ear and Head Tumors
- Streptococcal Infections and Treatments
- Genomics and Phylogenetic Studies
- Histone Deacetylase Inhibitors Research
- Cutaneous Melanoma Detection and Management
- Facial Nerve Paralysis Treatment and Research
- Adenosine and Purinergic Signaling
- Agricultural Economics and Practices
- Reconstructive Facial Surgery Techniques
- Protein Degradation and Inhibitors
- Appendicitis Diagnosis and Management
University of Bergen
2017-2023
Gopalganj Science and Technology University
2023
Bangladesh Agricultural University
2016-2020
National Institute of Nuclear Medicine & Allied Sciences
2020
Haukeland University Hospital
2017-2019
Chittagong Medical College
2018
Aligarh Muslim University
2018
St. Luke's International University
2018
Mawlana Bhashani Science and Technology University
2015
Karakoram International University
2013
Abstract Background Microtubes (MTs), cytoplasmic extensions of glioma cells, are important cell communication structures promoting invasion and treatment resistance through network formation. MTs abundant in chemoresistant gliomas, particular, glioblastomas (GBMs), while they uncommon chemosensitive IDH-mutant 1p/19q co-deleted oligodendrogliomas. The aim this study was to identify potential signaling pathways involved MT Methods Bioinformatics analysis TCGA performed analyze differences...
Despite the high prevalence of hospitalization for left iliac fossa tenderness, there is a striking lack randomized data available to guide therapy. The authors hypothesize that an oral antibiotic and fluids are not inferior intravenous (IV) antibiotics 'bowel rest' in clinically diagnosed acute uncomplicated diverticulitis.A controlled trial was constructed two District General Hospitals. All patients presenting with diverticulitis were eligible study. Oral IV regimens utilizing...
Glioblastoma multiforme (GBM) has a poor prognosis with an overall survival of 14–15 months after surgery, radiation and chemotherapy using temozolomide (TMZ). A major problem is that the tumors acquire resistance to therapy. In effort improve therapeutic efficacy TMZ, we performed genome‐wide RNA interference (RNAi) synthetic lethality screen establish functional gene signature for TMZ sensitivity in human GBM cells. We then queried Connectivity Map database search drugs would induce...
Abstract Background Suicide gene therapy for malignant gliomas has shown encouraging results in the latest clinical trials. However, prodrug application was most often restricted to short-term treatment (14 days), especially when replication-defective vectors were used. We previously showed that a substantial fraction of herpes simplex virus thymidine kinase (HSV-TK) transduced tumor cells survive ganciclovir (GCV) an orthotopic glioblastoma (GBM) xenograft model. Here we analyzed whether...
This report describes the clinical and radiographic findings together with surgical management of temporomandibular joint contents herniation through tympanic plate external auditory canal. Two patients are reported. A review literature is presented, including a brief discussion embryological development Excluding infection, trauma or neoplasm, defect in canal represents developmental aberration failure foramen Huschke to close during development. pre-auricular approach insertion fixation an...
Background: Chronic Heart Failure is a complex clinical conditions affecting patients' Quality of Life (QoL) globally. Objective: The aim the study was to identify factors influencing quality life chronic heart failure patients. Methods: A descriptive exploratory carried out by face-to-face interview with structured standard questionnaire. One hundred and forty two hospitalized patients were conveniently recruited from National Institute Cardiovascular Disease Hospital, Sher-e-Bangla Nagar,...
Knowledge on intra-specific genetic variation of an organism is important for its improvement and conservation. In order to estimate relatedness in eleven tropical Sugar beet varieties we used randomly amplified polymorphic DNA (RAPD) markers. The RAPD analysis was performed using six decamer random primers, which a total 63 fragments 43 (68.25%) were found polymorphic. average bands per primer 7.17 the overall gene diversity 0.24. Among loci studied, 2 specific 2K 310, 1 Shubraha, Natura...
Streptomyces xinghaiensis is a Gram-positive, aerobic and non-motile bacterium. The bacterial genome known. Therefore, it of interest to study the uncharacterized proteins in genome. An protein (gi|518540893|86 residues) was selected for comprehensive computational sequence-structure-function analysis using available data tools. Subcellular localization targeted with conserved residues assigned secondary structures documented. Sequence homology search against bank (PDB) non-redundant GenBank...
Pendahuluan : Kanker serviks merupakan salah satu penyakit yang disebabkan oleh infeksi Human Papiloma Virus (HPV) dan menyerang organ reproduksi perempuan. dapat dideteksi dini melalui pemeriksaan Inspeksi Visual Asetat (IVA test). Pemeriksaan IVA dilakukan secara mudah tidak memerlukan waktu lama pada hasil pemeriksaan. pasangan Usia Subur (PUS) berusia mulai 15 – 49 tahun, khususnya perempuan aktif seksual. Observasi awal bahwa sebagian besar menolak melakukan IVA. Tujuan: penelitian ini...
Bernhardt, J; Boldeman, C; Breitbart, E W; M; Christophers, E; Elvers, H; Gefeller, O; Henseler, T; Hutzler, D; Johnson, S; Karsa, L; Kölmel, K; Latif, Matthes, R; McKinlay, A F; Murphy, G; Newton, J A; Petres, Plentz, Repacholi, Sebastian, Shafir, Stein, Tilgen, Ullen, Weichenthal, M Author Information
Industrial wastewater is a major problem in Gazipur, Bangladesh which very cheaply available the surrounding area for crop production. An experiment was conducted at Farmer’s Field of Gazipur district to study effect irrigation water quality on yield boro rice. The comprised three varieties viz., BR14, BRRI dhan28 and dhan29 sources viz. fresh irrigation, mixed (fresh + industrial wastewater) irrigation. laid out split-plot design with replications where assigned main plot rice subplot....
Lentiviral vector mediated herpes simplex virus thymidine kinase (HSV-Tk)/ ganciclovir (GCV) therapy is a very promising therapeutic option for the treatment of glioblastoma (GBM). Although this leads to complete remission GBM in an orthotopic PDX model, recurrent tumors are observed, which contain fraction surviving Tk-GFP+ cells. Here, we hypothesize that prolonged prodrug could provide significant survival benefit through killing these remaining After intracranial implantation patient...
Background: To find out the renal morphological changes after Extracorporeal Shock Wave Lithotripsy (ESWL) both in short and long term. Materials methods: This prospective study was carried Department of Urology, Chittagong Medical College Hospital, from January 2009 to 2010. Patients with symptom, radio logically proved stone(s) measuring less than 2 cm diameter who are normotensive were enrolled this study. Results: All 50 patients divided into four age groups. The ranged 38 68 years...
Abstract Microtubes (MTs), cytoplasmic extensions of glioma cells, are important cell communication structures promoting invasion and treatment resistance through network formation. MTs abundant in chemoresistant gliomas, particular glioblastomas (GBMs), while they uncommon chemosensitive IDH-mutant 1p/19q co-deleted oligodendrogliomas. To identify potential signaling pathways involved MT formation we performed a bioinformatics analysis TCGA data showing that the TGF-β pathway is highly...
Abstract Suicide Gene therapy (SGT) has been regarded as a promising experimental treatment modality for high-grade gliomas several decades. However, large-scale clinical trials have failed so far. One hypothesis behind this failure is that, even though SGT directly kills the bulk of tumor cells, it fails to activate an efficient anti-tumor immune response. Indeed, despite extensive research on SGT, mechanism cell death caused by and its immunogenic significance are largely unknown. The most...
Transforming growth factor-β (TGF-β) is a cytokine with key role in tissue homeostasis and cancer. TGF-β signalling highly active glioblastomas (GBM) elevated activity has been associated poor clinical outcome. Here we report the of mediating formation membrane tubes (MTs), which are tubular cytoplasmic extensions forming important communication structures. We observed that stimulation promotes enhanced MT both vitro vivo. Blockade pathway using selective inhibitor (A8301) or administration...
Microtubes (MTs), which are cytoplasmic extensions of glioma cells, have recently been discovered as important cell communication structures. MTs abundant in chemoresistant 1p/19q non-codeleted tumors, particular glioblastomas, however scarce chemosensitive co-deleted oligodendrogliomas. Here we report that TGF-β is an mediator MT formation. TCGA data analysis revealed upregulation growth-factors and receptors versus tumors. stimulation vitro promotes enhanced formation a panel GBM stem...
Background: Present study was undertaken to evaluate the wound healing property of a Unani herbal ointment prepared by 10% hydroalcoholic extract Berg-e-Hena (leaves Lawsonia alba Lamk) and 05% destructive distillate resin Raal (Shorea robusta Gaertn) with 25% emulsifying wax 60% white petroleum jelly.