A5068078572- Evolutionary Psychology and Human Behavior
- Neuroendocrine regulation and behavior
- Psychology of Moral and Emotional Judgment
- Cultural Differences and Values
- Attachment and Relationship Dynamics
- Metabolism, Diabetes, and Cancer
- Neural and Behavioral Psychology Studies
- Functional Brain Connectivity Studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Neural dynamics and brain function
- Social and Intergroup Psychology
- Neurotransmitter Receptor Influence on Behavior
- Action Observation and Synchronization
- Face Recognition and Perception
- Death Anxiety and Social Exclusion
- Macrophage Migration Inhibitory Factor
- Psychosomatic Disorders and Their Treatments
- Cardiovascular Function and Risk Factors
- Evolutionary Game Theory and Cooperation
- Cancer, Hypoxia, and Metabolism
- Pancreatic function and diabetes
- Sirtuins and Resveratrol in Medicine
- Mitochondrial Function and Pathology
- Mental Health Research Topics
- Cardiac Ischemia and Reperfusion
Beijing Normal University
2016-2025
Chinese Institute for Brain Research
2016-2025
Yale University
2016-2024
State Key Laboratory of Cognitive Neuroscience and Learning
2018-2024
Beijing Chao-Yang Hospital
2024
Capital Medical University
2024
University of Malaya
2024
McGovern Institute for Brain Research
2015-2022
Capital Region of Denmark
2021
Indiana University
2021
Humans observe various peoples' social suffering throughout their lives, but it is unknown whether the same brain mechanisms respond to people we are close and strangers' suffering. To address this question, had participant's complete functional magnetic resonance imaging (fMRI) while observing a friend stranger experience exclusion. Observing friend's exclusion activated affective pain regions associated with direct (i.e. firsthand) of [dorsal anterior cingulate cortex (dACC) insula],...
Human adults usually respond faster to their own faces rather than those of others. We tested the hypothesis that an implicit positive association (IPA) with self mediates self-advantage in face recognition through 4 experiments. Using a self-concept threat (SCT) priming associated negative personal traits and led weakened IPA self, we found self-face advantage face-recognition task required identification orientation was eliminated by SCT priming. Moreover, effect on evident only left-hand...
Western cultures encourage self-construals independent of social contexts, whereas East Asian foster interdependent that rely on how others perceive the self. How are culturally specific mediated by human brain? Using functional magnetic resonance imaging, we monitored neural responses from adults in (Chinese) and (Danish) cultural contexts during judgments social, mental physical attributes themselves public figures to assess influences self-referential processing personal different...
Christianity strongly encourages its believers to surrender God and judge the self from God's perspective. We used functional MRI assess whether this religious belief is associated with neural correlates of self-referential processing distinct that non-religious people. Non-religious Christian participants were scanned while performing tasks personal-trait judgments regarding or public persons. found that, self-judgment was linked better memory traits related than others, induced increased...
The regulation of AMPK in the ischemic heart remains incompletely understood. Recent evidence implicates role Sestrin2 signaling pathway, and it is hypothesized that plays an influential during myocardial ischemia to promote activation. protein was found be expressed adult cardiomyocytes accumulated conditions. knockout (KO) mice were used determine importance reperfusion (I/R) injury. When wild-type (WT) KO subjected vivo I/R, infarct size significantly greater compared with WT hearts....
Starvation induces liver autophagy, which is thought to provide nutrients for use by other organs and thereby maintain whole-body homeostasis. Here we demonstrate that O-linked β-N-acetylglucosamine (O-GlcNAc) transferase (OGT) required glucagon-stimulated autophagy metabolic adaptation starvation. Genetic ablation of OGT in mouse livers reduces autophagic flux the production glucose ketone bodies. Upon glucagon-induced calcium signaling, calcium/calmodulin-dependent kinase II (CaMKII)...
Recent evidence suggests that the association between oxytocin receptor polymorphism (OXTR rs53576) and emotion-related behavioral/psychological tendencies differs individuals from East Asian Western cultures. What remains unresolved is which specific dimension of cultural orientations interacts with OXTR rs53576 to shape these whether such gene × culture interactions occurs at both behavioral neural level. This study investigated how interdependence—a key distinguish cultures—to affect...
Intergroup conflict contributes to human discrimination and violence, but persists because individuals make costly contributions their group's fighting capacity. Yet, how group members effectively coordinate during intergroup remains poorly understood. Here, we examine the role of oxytocin for (the coordination of) attack or defense in multi-round, real-time feedback contests. In a double-blind placebo-controlled study with N = 480 males Attacker-Defender Contests, found that reduced over...
Neural activity in the social brain network varies across individuals with different cultural traits and genetic polymorphisms. It remains unknown whether a specific polymorphism may influence association between neural network. We tested serotonin transporter promoter (5-HTTLPR) affects self-construals involved reflection of personal attributes oneself significant other (i.e., mother). Using functional MRI, we scanned Chinese adults short/short (s/s) or long/long (l/l) variants 5-HTTLPR...
Our recent work showed that close relationships result in shared cognitive and neural representations of the self one's mother collectivistic individuals (Zhu et al., 2007, Neuroimage, 34, 1310-7). However, it remains unknown whether others, such as mother, father best friend, are differentially represented brains. Here, using functional magnetic resonance imaging a trait judgment task, we evidence that, while judgments generated comparable activity medial prefrontal cortex (MPFC) anterior...
Human adults typically respond faster to their own face than the faces of others. However, in Chinese participants, this self-face advantage is lost presence one's supervisor, and they supervisor's own. While "boss effect" suggests a strong modulation self-processing influential social superiors, current study examined whether effect was true across cultures. Given wealth literature on cultural differences between collectivist, interdependent versus individualistic, independent...