A5100691513- Cancer-related molecular mechanisms research
- Liver Disease and Transplantation
- RNA modifications and cancer
- MicroRNA in disease regulation
- Autophagy in Disease and Therapy
- Organ Transplantation Techniques and Outcomes
- Liver Disease Diagnosis and Treatment
- Beetle Biology and Toxicology Studies
- Circular RNAs in diseases
The First Affiliated Hospital, Sun Yat-sen University
2024
Sun Yat-sen University
2024
First Hospital of Shanxi Medical University
2020
Shanxi Medical University
2020
Autophagy plays a vital role in hepatocellular carcinoma (HCC) pathogenesis. Long non-coding RNAs (lncRNAs) are considered regulators of autophagy, and the aim present study was to investigate prognostic value autophagy-related lncRNA (ARlncRNA) develop new signature predict 1-year 3-year overall survival (OS) HCC patients. Transcriptome clinical information patients obtained from The Cancer Genome Atlas database. A set ARlncRNAs identified by co-expression analysis, which seven (AC005229.4,...
Purpose: There is no golden noninvasive and effective technique to diagnose lymph node metastasis (LNM) for esophageal squamous cell carcinoma (ESCC) patients. Here, a classifier was proposed consisting of miRNAs screen ESCC patients with LNM from the ones without LNM. Methods: miRNA expression clinical data files 93 samples were downloaded TCGA as discovery set 119 similar dataset GSE43732 validation set. Differentially expressed (DE-miRNAs) analyzed between LASSO regression performed...
ABSTRACT Background Avatrombopag has been approved for elevating platelet counts in patients with chronic liver diseases (CLDs) accompanied by thrombocytopenia (TCP). However, limited research focuses on its safety and efficacy CLD during the perioperative period of transplantation (LT). Methods We retrospectively enrolled severe TCP who received avatrombopag LT analyzed therapeutic efficacy, changes counts, related adverse events. Comparisons were conducted between transplant recipients...