A5015981210- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Music Technology and Sound Studies
- Metal complexes synthesis and properties
- Neuroscience and Music Perception
- Music and Audio Processing
- Diverse Musicological Studies
- Metal-Catalyzed Oxygenation Mechanisms
- Magnetism in coordination complexes
- Multisensory perception and integration
- Musicology and Musical Analysis
- HIV/AIDS drug development and treatment
- Organometallic Complex Synthesis and Catalysis
- History, Culture, and Society
- Lanthanide and Transition Metal Complexes
- Computational Drug Discovery Methods
- Synthesis and Biological Evaluation
- Biochemical and Molecular Research
- Quantum Chromodynamics and Particle Interactions
- Crystallography and molecular interactions
- Particle physics theoretical and experimental studies
- N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
- Communication in Education and Healthcare
- Multicomponent Synthesis of Heterocycles
- Bioactive Compounds and Antitumor Agents
Universidade Nova de Lisboa
2022-2023
University of Lisbon
2012-2022
Nova Southeastern University
2020
Instituto Superior Técnico
2009-2015
Rede de Química e Tecnologia
2015
Instituto Politécnico de Lisboa
2012-2015
In-Q-Tel
2015
Universidade Lusófona
2008
Università di Camerino
2007
The University of Western Australia
2007
Reactions between CuCl2 and the functionalized scorpionate 2,2,2-tris(1-pyrazolyl)ethanol HOCH2C(pz)31 (pz = pyrazolyl) or 2,2,2-tris(1-pyrazolyl)ethyl methanesulfonate CH3SO2OCH2C(pz)32 yield corresponding water soluble CuII complexes [CuCl2{HOCH2C(pz)3}] 3 [CuCl2{CH3SO2OCH2C(pz)3}]24. In ligand shows typical N,N,N-coordination mode, whereas in dinuclear complex 4 it binds metal as a bidentate species. Compounds 1-4 have been characterized by IR, far-IR, elemental analysis (for 2-4) single...
A bstract measurement of the $$ {K}^{+}\to {\pi}^{+}\nu \overline{\nu} <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msup> <mml:mi>K</mml:mi> <mml:mo>+</mml:mo> </mml:msup> <mml:mo>→</mml:mo> <mml:mi>π</mml:mi> <mml:mi>ν</mml:mi> <mml:mover> <mml:mo>¯</mml:mo> </mml:mover> </mml:math> decay by NA62 experiment at CERN SPS is presented, using data collected in 2021 and 2022. This dataset was recorded, after modifications to beamline detectors, a higher instantaneous beam...
Abstract Cobalt( II ) porphyrin complexes catalyze reactions between ethyl diazoacetate (EDA) and styrenes to give the corresponding cyclopropanes with trans selectivity. The of other diazoalkanes olefins have also been carried out, mechanism reaction has investigated. Kinetic data stoichiometric support formation a diazoalkane cobalt‐porphyrin complex that reacts generate cyclopropane. Diethyl maleate fumarate are not formed in presence an excess olefin . On treatment EDA Co (TPP) (TPP =...
The new sterically hindered scorpionate tris(3-phenylpyrazolyl)methanesulfonate (Tpms(Ph))(-) has been synthesized and its coordination behavior toward a Cu(I) center, in the presence of 1,3,5-triaza-7-phosphaadamantane (PTA), N-methyl-1,3,5-triaza-7-phosphaadamantane tetraphenylborate ((mPTA)[BPh4]) or hexamethylenetetramine (HMT) studied. reaction between Li(Tpms(Ph)) (1) [Cu(MeCN)4][PF6] yields [Cu(Tpms(Ph))(MeCN)] (2) which, upon further acetonitrile displacement on with PTA, HMT,...
Areneruthenium(II) molecular complexes of the formula [Ru(arene)(Q)Cl], containing diverse 4-acyl-5-pyrazolonate ligands Q with arene = cymene or benzene, have been synthesized by interaction HQ and [Ru(arene)Cl(μ-Cl)]2 dimers in methanol presence sodium methoxide. The dinuclear compound [{Ru(cymene)Cl}2Q4Q] (H2Q4Q bis(4-(1-phenyl-3-methyl-5-pyrazolone)dioxohexane), existing RRuSRu (meso form), has prepared similarly. [Ru(cymene)(Q)Cl] reacts azide acetone, affording [Ru(cymene)(Q)N3]...
New (arene)ruthenium(II) derivatives containing neutral HL or anionic L(-) ligands (arene = p-cymene benzene, in general, particular HL(1) bis(pyrazol-1-yl)acetic acid and HL(2) bis(3,5-dimethylpyrazol-1-yl)acetic acid) have been synthesized analytically spectrally characterized. The form coordinate ruthenium a chelating kappa(2)-N,N'-bidentate fashion affording 1:1 of formula [Ru(arene)(HL)Cl]Cl, where the inner Cl can be replaced by phosphine. These show very high conductance values water,...
Abstract The production of stable phenoxyl radicals is undoubtedly a synthetic chemical challenge. Yet it useful way to gain information on the properties biological tyrosyl radicals. Recently, several persistent have been reported, but only limited variations could be achieved. Herein, we show that amide– o ‐substituted radical (i.e. with salicylamide backbone) can synthesised in manner, thereby permitting easy modifications made through amide bond. To study effect H‐bonding...
Abstract The experimental conditions (solvent, base, temperature and oxidant) for allylic benzylic oxidation reactions catalyzed by dirhodium(II)/N‐heterocyclic carbene (NHC) complexes were optimized the first time in this work. oxidations of cyclohexene fluorene used as model reactions. Two both types found, which resulted their ketone [aerobic conditions, 40 °C, 1 equiv. t BuOOH (TBHP)] or tert ‐butyl peroxide derivatives (anaerobic 25 2 TBHP). dirhodium(II) undergo a single‐electron...
The new potentially N4-multidentate pyridyl-functionalized scorpionates 4-((tris-2,2,2-(pyrazol-1-yl)ethoxy)methyl)pyridine (TpmPy, (1)) and 4-((tris-2,2,2-(3-phenylpyrazol-1-yl)ethoxy)methyl)pyridine (TpmPyPh, (2)) have been synthesized their coordination behavior toward FeII, NiII, ZnII, CuII, PdII, VIII centers has studied. Reaction of (1) with Fe(BF4)2·6H2O yields [Fe(TpmPy)2](BF4)2 (3), that, in the solid state, shows sandwich structure trihapto ligand via pyrazolyl arms, is completely...
Abstract The new dianionic dinickel(II) complex [NBu 4 ] 2 [Ni (L) {L 3– = trianionic form of 3,5‐di‐ tert ‐butyl‐2‐hydroxy‐ N ‐(2‐hydroxyethyl)benzamide} has been synthesised and characterised by 1 H, 13 C NMR IR spectroscopy, mass spectrometry, elemental analysis X‐ray crystallography. structure · EtOH CH 3 CN reveals a quasiplanar complex, each the Ni II ions possessing NO planar coordination sphere that results from ligation L in fashion through ‐amidate, O ‐phenolate O‐bridging...
By way of a multidisciplinary approach, this article advances the idea that our listening to certain practices contemporary art music (electroacoustic, classical contemporary, and electronic music) relies on precise connections early stage perception. These styles are characterised by essential sound configurations evolve in time, thus eliciting sensorial impact which transcends features regarding sources affective responses. Listeners grasp what Scruton calls ‘pure events’ ‘world sound’,...
Polycyclic aromatic hydrocarbons (PAHs) are persistent pollutants present in the environment with known mutagenic and carcinogenic properties. In study effects of exposure to single or multiple doses benzo[a]anthracene (BaA), pyrene (Pyr), 3 halogenated derivatives these compounds (1-chloropyrene, 1-bromopyrene [1-BrPyr], 7-chlorobenzo[a]anthracene [7-ClBaA]) were evaluated a liver-derived human cell line (HepG2). Cytotoxicity as assessed by classic...
The study of chelating ligands is undoubtedly one the most significant fields research in chemistry. present work directed to synthesis new functionalized derivatives tripodal C-scorpionate compounds. Tris-2,2,2-(1-pyrazolyl)ethanol, HOCH2C(pz)3 (1), important hydrotris(pyrazolyl)methane, was used as a building block for C-scorpionates, aiming expand scope this unexplored class first dendritic successfully prepared and industrial catalytic reactions, Sonogashira Heck C-C cross-couplings.
This paper enquires into the nature of connections between memory and certain genres contemporary art music whose unique features rely particularly on our early mnemonic processes. Specific sound configurations this are often associated, during listening, with visual tactile sensorial qualities abstract geometries. They perceived fundamentally as results acoustic-physical forces energies organized according to Gestalt kinesthetic principles. kind calls for a specific listening attitude,...
The synthesis and characterisation of the new di-compartmental bis-(2-hydroxyisophtalamide) macrocyclic pro-ligand, LH(6), which comprises two phenol-diamide units linked by ethylene bridges, is herein reported, together with its corresponding di-phenolate salt, [NBu(4)](2)[LH(4)]. three compounds, [LH(4)(OMe)(2)] (protected ligand), LH(6) [LH(4)][NBu(4)](2) were fully characterised including X-ray crystallography for results solid-state solution studies have indicated that macrocycle can...
We report the oxidation of first line anti-HIV drug efavirenz (EFV), mediated by a bio-inspired nonheme Fe-complex. Depending upon experimental conditions this system can be tuned either to yield major EFV metabolite, 8-hydroxy-EFV, in enantiomerically pure form or mimic cytochrome P450 (CYP) activity, yielding 8-hydroxy-EFV and 7-hydroxy-EFV, two phenolic metabolites reported formed vivo. The successful anti-estrogen tamoxifen equine estrogen equilin into their CYP-mediated supports general...
Quinoid electrophiles from the nevirapine metabolites, 2-OH- and 3-OH-nevirapine, react with nitrogen-based bionucleophiles yielding covalent adducts.
This article explores a particular perspective, shared across various contemporary musical currents, that focuses on sound itself as complex entity. Through the analysis of certain fundamental elements and sonic characteristics, this study develops new method for comparing different genres characterised by similar approach to sound. Using benefits audio, spectra score examinations, strategy is applied post-spectralist minimalist compositions (e.g. G. F. Haas, B. Lang, R. Nova, Verrando),...