A5054472594- Tryptophan and brain disorders
- Bladder and Urothelial Cancer Treatments
- Ginseng Biological Effects and Applications
- Eosinophilic Esophagitis
- Cell death mechanisms and regulation
- Anesthesia and Neurotoxicity Research
- Immune cells in cancer
- Animal Disease Management and Epidemiology
- Urinary Bladder and Prostate Research
- Viral Infections and Immunology Research
- Drug-Induced Hepatotoxicity and Protection
- Drug Transport and Resistance Mechanisms
- Gastric Cancer Management and Outcomes
- Helicobacter pylori-related gastroenterology studies
- Respiratory viral infections research
- Phytochemical Studies and Bioactivities
- Liver Disease Diagnosis and Treatment
Baotou Medical College
2019-2021
Yuhuangding Hospital
2018-2020
Qingdao University
2018-2020
Abstract This study was aimed at exploring the underlying mechanisms of ketamine in SV‐40 immortalized human ureteral epithelial (SV‐HUC‐1) cells. The viability and apoptosis SV‐HUC‐1 cells treated with 0.01, 0.1, 1 mM were respectively detected via cell counting kit‐8 (CCK‐8) assay terminal deoxynucleotidyl transferase‐mediated deoxyuridine triphosphate nick end labeling (TUNEL) staining. Reactive oxygen species (ROS) level measured through ROS probe Apoptosis‐related proteins (B‐cell...
Abstract Cerebral ischaemia is a common cerebrovascular disease and often induces neuronal apoptosis, leading to brain damage. Polygalasaponin F (PGSF) one of the components in Polygala japonica Houtt, it triterpenoid saponin monomer. This research focused on anti‐apoptotic effect PGSF during oxygen‐glucose deprivation reoxygenation (OGD/R) injury rat adrenal pheochromocytoma cells (PC12) primary cortical neurons. OGD/R treatment reduced viability PC12 was prevented by PGSF, as shown MTT...
What is known and objective Anti-tuberculosis drug-induced liver injury (ATLI) one of the most significant adverse reactions for this line therapy. N-acetyltransferase 2 (NAT2) an important metabolic enzyme involved in drug metabolism detoxification. Genetic polymorphism DNA methylation have been proven to be key factors that affect expression NAT2. Therefore, study was investigate relationship between NAT2 gene promoter region with ATLI risk Mongolian tuberculosis patients. Methods Our a...
Ketamine abusing is associated with ulcerative cystitis, but the mechanisms remain unclear. This study aimed to investigate existence of ketamine-induced symptom in a rat model and evaluate underlining mechanisms. Sprague-Dawley rats were chosen randomly divided into 12 groups (n = 8), such as control group, low dose ketamine (10 mg/kg/day), middle (30 mg/kg/day) high (50 groups. The experimental administrated i.p. daily, whereas saline. After 1, 3, 6 months treatment, bladder tissues...