A5029965226- Nutrition, Genetics, and Disease
- Pancreatic function and diabetes
- Immune Response and Inflammation
- Neuroinflammation and Neurodegeneration Mechanisms
- Genetic Associations and Epidemiology
- Health and Lifestyle Studies
- Diabetes and associated disorders
- Parkinson's Disease Mechanisms and Treatments
- Diet and metabolism studies
- Pesticide Exposure and Toxicity
- Obesity, Physical Activity, Diet
- Mitochondrial Function and Pathology
- Birth, Development, and Health
- Drug-Induced Hepatotoxicity and Protection
- Medicinal Plants and Bioactive Compounds
- Liver Disease Diagnosis and Treatment
- Metabolism and Genetic Disorders
- Retinal Diseases and Treatments
- Muscle and Compartmental Disorders
- Glycogen Storage Diseases and Myoclonus
- Diet, Metabolism, and Disease
- Barrier Structure and Function Studies
- Venous Thromboembolism Diagnosis and Management
- Multiple Sclerosis Research Studies
- Vitamin C and Antioxidants Research
Universidad de Guadalajara
2011-2023
Laboratorio Desarrollo-Envejecimiento; Enfermedades Neurodegenerativas. Division de Neurociencias. Centro Investigacion Biomedica Occidente (CIBO). Instituto Mexicano del Seguro Social (IMSS), Guadalajara, Jal. Mexico Departamento Biologia molecular y genomica. Universitario Ciencias la Salud (CUCS). Universidad Guadalajara. Quimica. Exactas e Ingenierias. Neurologia. Unidad Medica Alta Especialidad (UMAE). Hospital Especialidades (HE). Medico Nacional (CMNO), IMSS, Mexico. Departamento...
TJP1 gene encodes a ZO-1 protein that is required for the recruitment of occludins and claudins in tight junction, involved cell polarisation. It has different variations, frequency which been studied populations. In Mexico there are no studies this gene. These because their polymorphisms can be used associated with medicine surgery. Therefore, aim study was to estimate alleles genotypes rs2291166 polymorphism Mestizos population, conformational effect an amino acid change. A total 473...
Type 2 diabetes mellitus is a complex disease and global health problem; hence the first level of care should handle approaches medical genetics to reduce its incidence. In this manuscript we present perspectives study genomic medicine carried out in Mexican population, which show molecular heterogeneity according studied population. Genes currently associated are fifty, including ABCA1, APOE, BGLAP, LRP2, CYP19A1, hIAPP, SCARB1, TCF7L2, TNFA. Up date there no variants related HNF1β, INS,...
El gen TJP1 codifica para una proteína ZO-1, necesaria el reclutamiento de las ocludinas y claudinas en uniones estrechas participa la polarización celular. Tiene diferentes variaciones cuya frecuencia ha sido estudiada numerosas poblaciones; sin embargo México no hay estudios este gen, siendo necesarios ya que sus polimorfismos pueden ser usados asociación medicina cirugía. Por tal motivo objetivo estudio fue estimar alelos genotipos del polimorfismo rs2291166 población mestiza México; así...
those polymorphisms that lead to amino acid changes in critical domains of the protein are rs1038306187 leading change p.Gln791Glu domain guanylate kinase (Location residue 682-861).The ZU5 1701-1799) has 33 conformational (Table 1).Polymorphisms affect gene expression, by nucleotide at cryptic sites alternative splicing, such as rs781148827, rs5478300017, rs78014403 and rs1020739943 acceptor region, rs1029122894 donor region.None these have been explored for their pathogenic effect, which...