A5046734241- Hemoglobin structure and function
- Neonatal Health and Biochemistry
- Methemoglobinemia and Tumor Lysis Syndrome
- Liver Disease Diagnosis and Treatment
- Vector-Borne Animal Diseases
- Microbial infections and disease research
- Congenital Anomalies and Fetal Surgery
- Eosinophilic Disorders and Syndromes
- Cannabis and Cannabinoid Research
- Veterinary Oncology Research
- Coccidia and coccidiosis research
- Animal health and immunology
- Clinical Laboratory Practices and Quality Control
- Parasite Biology and Host Interactions
- Veterinary Pharmacology and Anesthesia
- Trypanosoma species research and implications
- Diet and metabolism studies
- Drug-Induced Hepatotoxicity and Protection
- Adrenal and Paraganglionic Tumors
- Veterinary Medicine and Surgery
- Ethics in Clinical Research
- Liver Disease and Transplantation
- Veterinary Equine Medical Research
- Pharmaceutical studies and practices
- Heme Oxygenase-1 and Carbon Monoxide
University of Prince Edward Island
1997-2020
Acetaminophen (APAP) overdose in most species is associated with hepatotoxicity because of the metabolite N ‐acetyl‐ p ‐benzoquinoneimine (NAPQI). In dogs and cats, APAP primarily causes methemoglobinemia hemolysis. Although NAPQI has been proposed as responsible intermediate it lacks chemical or pharmacokinetic characteristics that favor methemoglobin formation. We hypothesized para ‐aminophenol (PAP) rather than induces deficient arylamine ‐acetyltransferase (NAT) activity cats contributes...
A Clydesdale mare was examined for weight loss, inappetence, ptyalism, and dysphagia. The main abnormality revealed by serum biochemistry a marked hyperglobulinemia, protein electrophoresis monoclonal gammopathy in the gamma region. urine positive Bence Jones proteins. These findings suggested plasma cell tumor. neoplasm could not be located with extensive antemortem examination. At postmortem, neoplastic cells morphologically compatible equine IgG imunoperoxidase staining infiltrated...
Background Methemoglobin (met H b) is oxidized hemoglobin that cannot reversibly bind oxygen, and concentrations in healthy fish have been reported to be 0.6–24.8% compared with 0–3% mammals. In fish, met b has measured using spectrophotometric methods potassium cyanide ( KCN ), but not co‐oximetry, which the preferred method for human samples. Objectives The aims of this study were evaluate co‐oximetry as a measuring metHb O ncorhynchus mykiss , compare method, establish reference values...
Abstract A plant applied coating has been developed which protects pipelines during installation, hydrostatic testing and service in rocky terrain. The is up to 50 mm thick used eliminate the need for select backfill these areas. impact penetration resistant resists denting of pipe as well protecting corrosion without adversely affecting normal pipeline construction practices or shielding cathodic protection pipeline. Data presented on a 160 km gas transmission project where rockshield was...