A5055837807- Sociology and Education Studies
- Social and Demographic Issues in Germany
- Innovation, Technology, and Society
- COVID-19 and healthcare impacts
- Patient Satisfaction in Healthcare
- Cancer Genomics and Diagnostics
- Surgical Simulation and Training
- Glioma Diagnosis and Treatment
- Neurogenesis and neuroplasticity mechanisms
- Neuroinflammation and Neurodegeneration Mechanisms
- Telemedicine and Telehealth Implementation
- Cardiac, Anesthesia and Surgical Outcomes
- Veterinary Oncology Research
- Cancer Cells and Metastasis
- Respiratory viral infections research
- Immune cells in cancer
- Simulation-Based Education in Healthcare
- Abdominal Surgery and Complications
- Hospital Admissions and Outcomes
- Rabies epidemiology and control
- Antibiotics Pharmacokinetics and Efficacy
- Cardiovascular Conditions and Treatments
- Bird parasitology and diseases
- Veterinary Equine Medical Research
- Political Influence and Corporate Strategies
Carolinas Medical Center
2018-2023
Leipzig University
2017-2021
University of Prince Edward Island
2020-2021
University of Pennsylvania
2020
Technical University of Darmstadt
2015-2016
Postdischarge video-based virtual visits are a growing aspect of surgical care and have dramatically increased in the setting coronavirus disease 2019 (COVID-19) pandemic.To evaluate outcomes all-cause 30-day hospital encounter proportion among patients who postdischarge visit follow-up compared with in-person follow-up.Randomized, active, controlled noninferiority trial an urban setting, including from small community large, tertiary hospital. Patients underwent minimally invasive...
Abstract Irradiation is widely used to treat brain tumors, and also create bone marrow (BM) chimeras. BM chimeras are dissect functions origin of microglia blood‐derived mononuclear cells under homeostatic or pathological conditions. This facilitated by the fact that survive irradiation thus regarded radio‐resistant. In this study, we tested whether indeed radio‐resistant looked for potential mechanisms might explain phenomenon. We analyzed radio‐resistance independently their physiological...
Ionizing radiation (IR) exerts deleterious effects on the developing brain, since proliferative neuronal progenitor cells are highly sensitive to IR-induced DNA damage. Assuming a response that is comparable mammals, chick embryo would represent lower vertebrate model system allows analysis of mechanisms underlying this sensitivity, thereby contributing reduction, refinement and replacement animal experiments. Thus, study aimed elucidate embryonic retina in three selected stages. Our studies...
Abstract Cancer research requires models closely resembling the tumor in patient. Human tissue cultures can overcome interspecies limitations of animal or loss architecture vitro models. However, analysis slices is often limited to histology. Here, we demonstrate that are also suitable for whole transcriptome sequencing and present a method automated histochemistry slices. Tumor peritumoral from patient with glioblastoma was processed slice cultures, which were treated standard therapy...
Abstract Pruning, the elimination of excess synapses is a phenomenon fundamental importance for correct wiring central nervous system. The establishment cerebellar climbing fiber (CF)‐to‐Purkinje cell (PC) synapse provides suitable model to study pruning and pruning‐relevant processes during early postnatal development. Until now, role microglia in remains under intense investigation. Here, we analyzed migration into cortex development their possible contribution CF‐to‐PC synapses. Microglia...
Abstract Radiopaque densities can be observed on imaging after the ingestion of either foreign bodies or some medications. Our case report discusses an 11-year-old boy with autism spectrum disorder and attention deficient who presented to emergency department because concerns for constipation dehydration. Incidentally, abdominal x-ray showed numerous radiopaque throughout his intestines in addition constipation. He was admitted, home regimen reviewed attempt identify a potential source these...
A 4-yr-old female central bearded dragon (Pogona vitticeps) with a history of tenesmus was found dead 1 month after surgical debulking palpable caudal coelomic mass. At necropsy, 2.5-cm-diameter, firm, lobulated, tan–yellow mass associated the wall pelvic canal and bilateral masses were present in pharynx (0.6 3.0 cm diameter), largest which soft dark red. Histologically, within arose from consisted primarily fibrocollagen myxoid to cystic regions, mixed inflammatory infiltrates. Additional...
One of the major challenges in cancer research is finding models that closely resemble tumors within patients. Human tissue slice cultures are a promising approach to provide model patient's tumor biology ex vivo. Recently, it was shown these slices can be successfully analyzed by whole transcriptome sequencing as well automated histochemistry, increasing their usability preclinical model. Glioblastoma multiforme (GBM) highly malignant brain with poor prognosis and little known about its...
Nasal mucosa and olfactory bulb are separated by the cribriform plate which is perforated nerves. We have previously demonstrated that permissive for T cells monocytes viruses can enter upon intranasal injection axonal transportation. Therefore, we hypothesized nasal equipped to deal with constant infectious threats. To detect genes involved in this process, compared gene expression of mice kept under specific pathogen free (SPF) conditions on non-SPF using RNA deep sequencing. found massive...