A5029253729- Endometrial and Cervical Cancer Treatments
- Corneal Surgery and Treatments
- Ovarian cancer diagnosis and treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Retinal and Macular Surgery
- Cardiac electrophysiology and arrhythmias
- Ear and Head Tumors
- Breast Cancer Treatment Studies
- Olfactory and Sensory Function Studies
- Pharmacy and Medical Practices
- Advanced biosensing and bioanalysis techniques
- Uterine Myomas and Treatments
- Allergic Rhinitis and Sensitization
- Ferroelectric and Negative Capacitance Devices
- Simulation-Based Education in Healthcare
- Ion channel regulation and function
- Cardiac Arrhythmias and Treatments
- Advanced Memory and Neural Computing
- Corneal surgery and disorders
- Innovations in Medical Education
- Intraocular Surgery and Lenses
- Advanced Chemical Sensor Technologies
- Family and Patient Care in Intensive Care Units
- Head and Neck Surgical Oncology
- Glaucoma and retinal disorders
University of Michigan–Ann Arbor
2020-2023
TU Dresden
2022
University of Michigan–Dearborn
2019-2020
Beaumont Health
2020
Loss-of-function (LOF) variants in SCN1B, encoding the voltage-gated sodium channel β1/β1B subunits, are linked to neurological and cardiovascular diseases. Scn1b-null mice have spontaneous seizures ventricular arrhythmias die by approximately 21 days after birth. Subunits play critical roles regulating excitability of cardiomyocytes maintaining rhythmicity. However, whether they also regulate atrial is unknown. We used neonatal model effects SCN1B LOF on physiology pediatric patients. Scn1b...
Abstract Glioblastoma (GBM) is the most frequent and inevitably lethal primary brain cancer in adults. It recognized that overexpression of endosomal Na + /H exchanger NHE9 a potent driver GBM progression. Patients with have threefold lower median survival relative to patients normal expression, using available treatment options. New strategies tailored for this subset are much needed. According prevailing model, leads an increase plasma membrane density epidermal growth factor receptors...
Despite faster healing and reduced risk of rejection, some surgeons are hesitant to adopt Descemet membrane endothelial keratoplasty (DMEK) due difficult intraoperative tissue preparation. Use eye bank prestripped, prestained, preloaded (p3) DMEK can reduce the learning curve complications.We conducted a prospective study including 167 eyes undergoing p3 compared outcomes retrospective chart review 201 that underwent standard surgery. The primary were graft failure, detachment, re-bubbling...
Purpose: There is no current standard treatment regimen for carcinoma ex pleomorphic adenoma (CXPA) of the lacrimal gland. Neoadjuvant intraarterial cytoreductive chemotherapy (IACC) followed by multimodal therapy has achieved good locoregional control in adenoid cystic We reviewed our experience with neoadjuvant IACC CXPA Methods: Three patients gland treated ICAA at University Michigan were retrospectively reviewed. Results: had stage T4cN0M0 (American Joint Committee on Cancer 8th ed)....
Uterine serous carcinoma (USC) is a rare but aggressive endometrial cancer histology. We reviewed outcomes for patients with USC to identify the best adjuvant treatment strategy.We retrospectively identified 162 The International Federation of Gynecology and Obstetrics (FIGO) stage I-IVA treated at our institution. Baseline characteristics, details, clinical outcomes, toxicity data were recorded.Median follow-up was 3.4 years (0.3-26 years). A variety therapy strategies employed: 14% no...
The aim of the study was to investigate whether olfactory fluctuations (OF) are pronounced in patients with sinonasal dysfunction (OD).The retrospective investigation included aged 18 years or older, who consulted a tertiary referral center for loss. Patients normal smell function were excluded. answered structured questionnaire about their symptoms, specific questions related presence OF and its average frequency, amplitude, duration, time since most recent OF, associated symptoms...
Purpose: The aim of this study was to evaluate outcomes vitreoretinal surgery with temporary keratoprosthesis combined penetrating keratoplasty. Setting: conducted at a university-based corneal and retinal disease referral practice, Ann Arbor, MI. Methods: This is retrospective analysis 43 patients who underwent Functional (best-corrected visual acuity transplant survival rate) anatomical (clear graft attachment) were measured. Results: Both attachment evaluated. There no difference in...