A5069220548- Neurotransmitter Receptor Influence on Behavior
- Language and cultural evolution
- Tryptophan and brain disorders
- Genomics and Chromatin Dynamics
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- RNA Research and Splicing
- Hypothalamic control of reproductive hormones
- Neuroscience and Neuropharmacology Research
- RNA modifications and cancer
- Complex Systems and Time Series Analysis
- Reproductive Biology and Fertility
- Evolutionary Game Theory and Cooperation
Massachusetts General Hospital
2021-2024
Harvard University
2021
Rice University
2017-2020
Baylor College of Medicine
2017
Abstract Throughout the Holocene, societies developed additional layers of administration and more information-rich instruments for managing recording transactions events as they grew in population territory. Yet, while such increases seem inevitable, are not. Here we use Seshat database to investigate development hundreds polities, from multiple continents, over thousands years. We find that sociopolitical is dominated first by growth polity scale, then improvements information processing...
Abstract Gonadotropin-releasing hormone (GnRH) neurons in the hypothalamus play a key role regulation of reproductive function. In this study, we sought an efficient method for generating GnRH from human embryonic and induced pluripotent stem cells (hESC hiPSC, respectively). First, found that exposure primitive neuroepithelial cells, rather than neuroprogenitor to fibroblast growth factor 8 (FGF8), was more effective neurons. Second, addition kisspeptin FGF8 further increased efficiency...