A5001658123- Antibiotic Resistance in Bacteria
- Vibrio bacteria research studies
- Pharmaceutical and Antibiotic Environmental Impacts
- Streptococcal Infections and Treatments
- Aquaculture disease management and microbiota
- Infective Endocarditis Diagnosis and Management
- Salmonella and Campylobacter epidemiology
- Bacterial biofilms and quorum sensing
- Neonatal and Maternal Infections
- Antibiotics Pharmacokinetics and Efficacy
- Bacterial Infections and Vaccines
- Escherichia coli research studies
- Enterobacteriaceae and Cronobacter Research
- Bacteriophages and microbial interactions
- Genomics and Phylogenetic Studies
- Gut microbiota and health
- Infections and bacterial resistance
- Amino Acid Enzymes and Metabolism
- Infectious Encephalopathies and Encephalitis
- Antimicrobial Resistance in Staphylococcus
- Clostridium difficile and Clostridium perfringens research
- Identification and Quantification in Food
- Neuroscience and Neuropharmacology Research
- Plant Pathogenic Bacteria Studies
- Biochemical and Structural Characterization
Hiroshima University
1984-2024
National Institute of Health Sciences
2017-2023
Oita University
2022
Food Research Institute
2020
Osaka University
2010-2019
National Institute of Infectious Diseases
2013-2018
Osaka International University
2014-2017
Osaka Prefecture University
2017
Ministry of Public Health
2011
University of Phayao
2011
Although studies have reported numerous effects of coffee on human health, few examined its specific gut microbiota. This study aimed to clarify the influence and galacto-oligosaccharide (GOS) consumption microbiota host responses. After mice consumed GOS, their intestines were sampled, bacterial counts measured with quantitative RT-PCR. Results showed that GOS significantly increased total bacteria in proximal colon. Escherichia coli Clostridium spp. decreased colon, Bifidobacterium...
Abstract To examine associations between clinical features of Streptococcus suis serotype 2 infections in humans Thailand and genotypic profiles isolates, we conducted a retrospective study during 2006–2008. Of 165 patients for whom bacterial cultures blood, cerebrospinal fluid, or both were positive S. 2, the major multilocus sequence types (STs) found ST1 (62.4%) ST104 (25.5%); latter is unique to Thailand. Clinical examined 158 patients. Infections sporadic; case-fatality rate adults was...
Background: Contamination of food with multiantibiotic-resistant bacteria, particularly extended-spectrum β-lactamase (ESBL)–producing Enterobacteriaceae, is considered a potential source for the wide dissemination ESBL-producing bacteria in communities. However, little known about extent contamination Vietnam. Objective: This study was conducted to assess characteristics Escherichia coli isolated from retail meats and shrimp Nha Trang, Materials Methods: A total 350 samples (poultry...
Background. Streptococcus suis is an emerging zoonotic pathogen, and causes sepsis meningitis in humans. Although sequence type (ST) 1 ST104 strains are capable of causing sepsis, ST1 commonly cause meningitis. In this study, we investigated the role suilysin, a member cholesterol-dependent cytolysins, differential pathogenicity between strains. Methods. The levels transcription translation sly gene messenger RNA both ST were compared by means quantitative polymerase chain reaction Western...
Background Streptococcus suis infection in humans has received increasing worldwide recognition. Methods and Findings A prospective study of S. was conducted Phayao Province northern Thailand to determine the incidence risk behaviors disease this region 2010. Thirty-one cases were confirmed. The case fatality rate 16.1%, estimated 6.2 per 100,000 general population. peak occurred May. median age patients 53 years 64.5% men. Consumption raw pork products confirmed 22 incubation period (range)...
Abstract: Recent studies have reported a widespread distribution of extended-spectrum β-lactamase (ESBL)-producing bacteria, not only in the nosocomial setting, but also community; some local communities Southeast Asia been to show high prevalence ESBL-producing bacteria. However, details regarding quantitative/qualitative state bacterial spread are currently unclear. Thus, aim this study was assess community residents from Indochinese peninsula, as representative region Asia. In order...
Colistin is indicated for the treatment of multidrug-resistant gram-negative bacterial infections. However, spread colistin-resistant bacteria harbouring an mcr gene has become a serious concern. This study investigated local foods in Vietnam contamination with bacteria. A total 261 extended-spectrum β-lactamase (ESBL)- and AmpC-producing Escherichia coli isolates from 330 meat seafood products were analysed colistin susceptibility presence genes. Approximately, 24% (62/261) ESBL- or E....
AbstractStreptococcus suis is an important zoonotic pathogen in swine and humans that causes sepsis meningitis. Our previous study Thailand showed the prevalence of S. infection humans, especially northern areas Thailand, transmission occurred mainly through consumption traditional raw pork products. Considering high incidence proportion mortality rate disease as public health problem, we implemented a food safety campaign Phayao Province 2011. We evaluated effects by comparing...
This study investigated the existence of sulfonamides and colistin resistance genes among extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli recovered from fish gut in Vietnam evaluated susceptibility patterns ESBL-producing E. to relevant antimicrobials. A total 88 isolates were analysed for presence ESBLs, sul (1, 2, 3) mcr (1–3) by PCR. Antimicrobial phenotypes determined disc diffusion. Results showed that: (i) high prevalence 94·3% sulfonamide was observed isolates....
Widespread dissemination of extended-spectrum β-lactamase (ESBL)-producing bacteria is a threat to public health. Since livestock products are possible reservoirs ESBL-producing bacteria, food-borne and the characteristics such organisms in food should be assessed evaluate potential sources contamination. A total 253 samples from poultry, pork, shrimp, fish were collected local markets rural area Vietnam 2013 2014. Escherichia coli isolated these samples, their ESBL genotypes, phylogenetic...
Due to increasing colistin usage, the dissemination of colistin-resistant gene mcr-1 has been increasingly investigated. The aim this study was determine whether a traveler on short-term international trip developing country could bring back their home country.Thirty-four travel events from Japan Vietnam encompassing 19 travelers were assessed. A fecal specimen collected each before and after event inoculated CHROMagar containing cefotaxime (CTX). Three seven colonies exhibiting...
Aim: To investigate the effects of Bacillus subtilis, licheniformis and megaterium in terms toxin growth pathogenic Vibrio harveyi. Methods Results: Three probionts were isolated from probiotic BZT aquaculture identified using a 16S rDNA sequence. Growth inhibition assay showed that supernatants 24‐h culture three species able to inhibit V. harveyi (LMG 4044); B. subtilis was most effective based on well diffusion method. Results liquid model also widely inhibiting strains (isolated...
Transmission of extended-spectrum β-lactamase (ESBL) genes has increased the global prevalence ESBL-producing bacteria, especially in developing countries. Human infection with these bacteria may be food-mediated but not been fully elucidated. Therefore, we aimed to examine edible river fish and elucidate their potential for horizontal gene transfer. A total 173 Enterobacterales were isolated (
Vibrio harveyi strains isolated from shrimp farms (wild strains) were compared with those culture collections in terms of minimum inhibitory concentration (MIC) and toxicity. Wild had higher MIC values for four antibiotics (kanamycin, carbenicillin, oxytetracycline ampicillin) also showed toxicity collection strains. the lowest antibacterial resistance was chosen to test if a gradual increase antibiotic frequent subculture would enhance its resistance. Results that V. able develop...
Extended-spectrum β-lactamase (ESBL)-producing Escherichia coli were isolated from wild and cultured fish (18 striped catfish, Pangasianodon hypophthalmus, 18 red tilapia, Oreochromis sp.) in the Mekong Delta, Vietnam, June 2014 to October 2014. In total, 39% of harbored ESBL-producing E. coli, including 44.4% 36.1% fish. The isolates highly resistant ampicillin, cefotaxime, trimethoprim-sulfamethoxazole, nalidixic acid among antibiotics tested. Cephalexin (4/16, 25%), cefazolin (1/16, 6%),...
The transmission of potentially life-threatening plasmid-mediated antibiotic-resistant bacteria poses a major threat to public health. This study aimed determine the presence commonly observed plasmids encoding antibiotic-resistance genes in Salmonella and Escherichia coli isolates from fishery products. Eighty river fishes were purchased retail stores supermarkets Vietnam. Only Salmonella-positive used for E. isolation. serotyping was performed using antisera. Isolated bacterial DNA...
Abstract Food contamination with plasmid‐mediated antibiotic‐resistant Escherichia coli has not been thoroughly investigated. This study aimed to clarify the prevalence of colistin‐resistant AmpC/extended‐spectrum β‐lactamase (ESBL)‐producing E. harbouring mcr (COL‐ESBL‐EC) and determine antibiotic resistance by comparison AmpC/ESBL‐producing (ESBL‐EC) (COL‐EC). Sixty chicken meats were tested for COL‐ESBL‐EC contamination. The result showed that 64 isolated from 66.7% samples, compared...
Campylobacter jejuni is one of the leading causes gastrointestinal illness worldwide and mainly transmitted from chicken through food chain. Previous studies have provided increasing evidence that this pathogen can colonize replicate in broiler during its breeding; however, temporal kinetics laying hen are poorly understood. Considering possible interaction between C. gut microbiota, current study was conducted to address dynamics cecum over 40 weeks, with alteration microbiota fatty acid...