A5100692599- Electrocatalysts for Energy Conversion
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Advanced battery technologies research
- Catalytic Processes in Materials Science
- CO2 Reduction Techniques and Catalysts
- Synthesis and Catalytic Reactions
- Catalytic C–H Functionalization Methods
- Electrochemical Analysis and Applications
- Metal-Catalyzed Oxygenation Mechanisms
- Metal complexes synthesis and properties
- Radical Photochemical Reactions
- Asymmetric Synthesis and Catalysis
- Chemical Synthesis and Analysis
- Oxidative Organic Chemistry Reactions
- Asymmetric Hydrogenation and Catalysis
- Vanadium and Halogenation Chemistry
- Cyclopropane Reaction Mechanisms
- Peptidase Inhibition and Analysis
- Catalytic Cross-Coupling Reactions
- Synthesis and Biological Evaluation
- N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
- Porphyrin and Phthalocyanine Chemistry
- Graphene and Nanomaterials Applications
- Nanoparticle-Based Drug Delivery
National Tsing Hua University
2021-2025
Guizhou University
2022-2023
University of Pennsylvania
2021-2022
University of Wisconsin–Madison
2017-2020
Fudan University
2019
University of Science and Technology of China
2016
National Taiwan University
2009
A complex role for chlorine radicals Radicals are atoms or molecules that highly reactive because they have an unpaired electron. common means of investigating whether involved in a particular reaction is to try trap them with acceptor compound. Yang et al. reinvestigated photoinduced alkane oxidation which trapping study had previously implicated alkoxy radicals. Their spectroscopic, kinetic, and isotopic labeling studies revealed chlorine, rather than alkoxy, was the key radical...
A series of mononuclear pseudomacrocyclic cobalt complexes have been investigated as catalysts for O2 reduction. Each these complexes, with CoIII/II reduction potentials that span nearly 400 mV, mediate highly selective two-electron to H2O2 (93–99%) using decamethylferrocene (Fc*) the reductant and acetic acid proton source. Kinetic studies reveal rate exhibits a first-order dependence on [Co] [AcOH], but no [O2] or [Fc*]. linear correlation is observed between log(TOF) vs E1/2(CoIII/II)...
The selective reduction of O2, typically with the goal forming H2O, represents a long-standing challenge in field catalysis. Macrocyclic transition-metal complexes, and cobalt porphyrins particular, have been focus extensive study as catalysts for this reaction. Here, we show that mononuclear Co-tetraarylporphyrin complex, Co(porOMe) (porOMe = meso-tetra(4-methoxyphenyl)porphyrin), catalyzes either 2e-/2H+ or 4e-/4H+ O2 high selectivity simply by changing identity Brønsted acid...
The oxygen reduction reaction catalyzed by homogeneous cobalt macrocycles typically leads to selective 2e–/2H+ of O2 H2O2. Variations in the conditions make it difficult compare performance characteristics different catalysts, however, and limits ability leverage insights design improved catalysts. Here, we show that free energy relationships between logarithm turnover frequency [log(TOF)] effective overpotential (ηeff) for ORR enable systematic comparison catalytic diverse Co–macrocycles...
A soluble, bis-ketiminate-ligated Co complex [Co(N2O2)] was recently shown to catalyze selective reduction of O2 H2O2 with an overpotential as low 90 mV. Here we report experimental and computational mechanistic studies the Co(N2O2)-catalyzed reaction (ORR) decamethylferrocene (Fc*) reductant in presence AcOH MeOH. Analysis Co/O2 binding stoichiometry kinetic support pathway involving a mononuclear cobalt species. The catalytic rate exhibits first-order dependence on [AcOH], but no [Fc*] or...
Construction of efficient doxorubicin (DOX) delivery systems addressing a cascade physiological barriers remains great challenge for better therapeutic efficacy tumors. Herein, we design well-defined enzyme-responsive peptide-linked block copolymer, PEG-GPLGVRGDG-P(BLA-co-Asp) [PEG and P(BLA-co-Asp) are poly(ethylene glycol) partially hydrolyzed poly(β-benzyl l-aspartate) (PBLA), respectively] (P3), with modular functionality DOX. The copolymers were successfully obtained via click reaction...
A photochemical C(sp 3 )–H oxygenation of arene and alkane substrates (including methane) catalyzed by [NEt 4 ] 2 [Ce IV Cl 6 under mild conditions (1 atm, 25 °C) is described.
An unprecedented example of skeletal editing pyrrolidines to 1,2-oxazinanes expands the applicability scope “single-atom” skeletal-editing technologies.
This study focuses on enhancing the water oxidation reaction (WOR) efficacy of dinuclear cobalt complex catalysts from both kinetic (turnover frequency, TOF) and thermodynamic (overpotential, η) perspectives. For this purpose, we synthesized six complexes 1-6 comprising non-innocent ligands with different electronically active substituents (-OMe (1), -Me (2), -H (3), -F (4), -Cl (5), -CN (6)). The electronic effects electrochemical WOR under neutral, acidic, alkaline conditions were...
Developing efficient methods for preparing privileged chiral ligands is an important endeavor in synthetic chemistry.
The impact of primary and secondary coordination spheres on Ru-based water oxidation catalysts is analyzed from kinetics (turnover frequency, TOF) thermodynamics (overpotential, η ) perspectives.
Abstract In this study, dinuclear cobalt complexes ( 1 and 2 ) featuring bis(benzimidazole)pyrazolide‐type ligands H L Me were prepared evaluated as molecular electrocatalysts for water oxidation. Notably, bearing a non‐innocent ligand displayed faster catalytic turnover than under alkaline conditions, the base dependence of oxidation kinetic isotope effect analysis indicated that reaction mediated by proceeded different mechanism relative to . Spectroelectrochemical, cold‐spray ionization...
Abstract The catalytic oxidation of water and C(sp 3 )−H bonds enables the conversion solar/electrochemical energy into chemical alcohol fuel production, respectively, therefore plays important roles in conversion/storage. These transformations are typically catalyzed by highly active complexes earth‐abundant first‐row transition metals (Mn, Fe, Co, Ni, Cu) with tetra‐amido macrocyclic ligands (TAMLs), although related kinetics thermodynamics remain underexplored. This review uses free...
Electrochemical water oxidation is known as the anodic reaction of splitting. Efficient design and earth-abundant electrocatalysts are crucial to this process. Herein, we report a family catalysts (1–3) bearing bis(benzimidazole)pyrazolide ligands (H2L1–H2L3). H2L3 contains electron-donating substituents noninnocent components, resulting in catalyst 3 exhibiting unique performance. Kinetic studies show first-order kinetic dependence on [3] [H2O] under neutral alkaline conditions. In contrast...
A series of hemilabile ligands α-aminoaldimines and their methylpalladium complexes have been prepared characterized. Neutral square-planar in the form [R1R2NCMe2CH═NR]Pd(Me)Cl (R = Me, R1 R2 Me (3a); R Et (3b); Et, (4a); nPr, (5a); iPr, (6a); (6b); (R1, R2) c-C4H8 (6c); H (6d); tBu, (6e); (7a); (7b); (7c); (7d); (7e); Ph, (8a); (8b)) show geometrical isomerism. The relative ratios trans/cis isomers appear to be predominated by steric hindrance between Pd-bound methyl group imino or amino...
Herein, the first example of umpolung α-regioselective 1,3-dipolar cycloaddition optically pure perhydroindole-2-carboxylic acid 1a with pyridinecarboxaldehydes 2 is described.
The water oxidation reaction (WOR), which is pivotal to storing energy in chemical bonds, requires a catalyst overcome its inherent kinetic barrier. In bulk solutions, sacrificial oxidants (SOs) can regenerate the catalysts ensure that homogeneous WOR be operated with long-term consistent performance. To implement this strategy for organic systems, we modified four common SOs tetra-