A5002467698- Lung Cancer Treatments and Mutations
- Lung Cancer Research Studies
- Isotope Analysis in Ecology
- Cancer Immunotherapy and Biomarkers
- Coastal wetland ecosystem dynamics
- Marine and fisheries research
- Land Use and Ecosystem Services
- Marine and coastal plant biology
- Marine Bivalve and Aquaculture Studies
- Cancer therapeutics and mechanisms
- American Environmental and Regional History
- Geology and Paleoclimatology Research
- Fish Ecology and Management Studies
- Lymphoma Diagnosis and Treatment
- Coastal and Marine Dynamics
- RNA modifications and cancer
- Lung Cancer Diagnosis and Treatment
- Cytokine Signaling Pathways and Interactions
- Fire effects on ecosystems
- Urban Stormwater Management Solutions
- Cryospheric studies and observations
- Water-Energy-Food Nexus Studies
- Botany, Ecology, and Taxonomy Studies
- Marine animal studies overview
- Coral and Marine Ecosystems Studies
The Nature Conservancy
2017-2023
San Diego State University
2022
University of Washington
2011-2020
Seattle University
2011
Humans are changing the Earth's surface at an accelerating pace, with significant consequences for ecosystems and their biodiversity. Landscape transformation has far-reaching implications including reduced net primary production (NPP) available to support ecosystems, energy supplies consumers, disruption of ecosystem services such as carbon storage. Anthropogenic activities have global NPP terrestrial by nearly 25%, but loss from wetland is unknown. We used a simple approach estimate...
Abstract Estuarine food webs are fueled by multiple different primary producers. However, identifying the relative importance of each producer to consumers is difficult, particularly for fishes that utilize sources due both their mobility and generally high trophic levels. Previous studies have documented broad spatial differences in producers within Upper San Francisco Estuary, California, including separation between pelagic littoral webs. In this study, we evaluated adult three closely...
Tidal marsh wetlands provide important foraging habitat for a variety of estuarine fishes. Prey organisms include benthic–epibenthic macroinvertebrates, neustonic arthropods, and zooplankton. Little is known about the abundance distribution interior macroinvertebrate communities in San Francisco Estuary (estuary). We describe seasonal, regional, site variation composition neuston macroinvertebrates that inhabit tidal channels, relate these patterns to environmental conditions. also spatial...
To evaluate the role of restoration in recovery Delta ecosystem, we need to have clear targets and performance measures that directly assess ecosystem function. Primary production is a crucial process, which limits quality quantity food available for secondary consumers such as invertebrates fish. The has low rate primary production, but it unclear whether this was always case. Recent analyses from Historical Ecology Team Landscapes Project provide quantitative comparisons areal extent 14...
We measured the influence of landscape setting on estuarine food web connectivity in five macrotidal Pacific Northwest estuaries across a gradient freshwater influence. used stable isotopes (δ13 C, δ15 N, δ34 S) combination with Bayesian mixing model to trace primary producer contributions suspension- and deposit-feeding bivalve consumers (Mytilus trossulus Macoma nasuta) transplanted into three vegetation zones: emergent marsh, mudflat, eelgrass. Eelgrass includes both Japanese eelgrass...
Abstract Urbanization-driven landscape changes are harmful to many species. Negative effects can be mitigated through habitat preservation and restoration, but it is often difficult prioritize these conservation actions. This due, in part, the scarcity of species response data, which limit predictive accuracy modeling estimate critical thresholds for biological decline recovery. To address challenges, we quantify effort required combination with a clear objective associated metric (e.g.,...
The State of Washington, USA, has set a goal to reach net zero greenhouse gas emissions by 2050, the year around which Intergovernmental Panel on Climate Change (IPCC) recommended we must limit global warming 1.5 °C above that pre-industrial times or face catastrophic changes. We employed existing approaches calculate potential for suite Natural Solution (NCS) pathways reduce Washington’s under three implementation scenarios: Limited, Moderate, and Ambitious. found NCS could between 4.3 8.8...
Forest thinning and gap creation are being implemented across the western United States of America (USA) to reduce wildfire forest mortality risk as climate warms. The Eastern Cascades in Washington, USA, is a transitional zone between maritime continental conditions represents data observations describing relationship density snowpack. We collected 3 years snow range densities characterize how management efforts this region may influence magnitude duration storage. Observations indicate...
<p>Clinicopathologic Features of EGFR-Mutant and ALK-Positive Patients Included in PD-L1 Expression Analysis</p>
<p>A-C): Images of autopsy specimens from an ALK-positive NSCLC patient, demonstrating heterogeneous expression PD-L1 in multiple sections examined (Diffuse A-B and focal C).</p>
<p>PD-L1 expression in FFPE samples with anti-PD-L1 antibody (clone E1L3N): A) Positive control (HDLM2 cell line known PD-L1 expression). B) Negative (PC3 line).</p>
<p>Quantitative image-based CD8+ TILs in baseline specimens of EGFR-mutant versus KRAS-mutant patients.</p>