- Renal Diseases and Glomerulopathies
- Chronic Kidney Disease and Diabetes
- Acute Kidney Injury Research
- Ectopic Pregnancy Diagnosis and Management
- Urinary Tract Infections Management
- Genetic factors in colorectal cancer
- Atherosclerosis and Cardiovascular Diseases
- Molecular Biology Techniques and Applications
- Brain Metastases and Treatment
- Healthcare and Venom Research
- Temporomandibular Joint Disorders
- Microwave-Assisted Synthesis and Applications
- Lung Cancer Treatments and Mutations
- Cancer-related molecular mechanisms research
- Muscle and Compartmental Disorders
- Musculoskeletal pain and rehabilitation
- Gut microbiota and health
- Forensic and Genetic Research
- Vasculitis and related conditions
- Autoimmune Bullous Skin Diseases
- Medical Research and Treatments
- Facial Nerve Paralysis Treatment and Research
- Systemic Lupus Erythematosus Research
- Nephrotoxicity and Medicinal Plants
- Platelet Disorders and Treatments
Second Xiangya Hospital of Central South University
2023
Central South University
2023
First Affiliated Hospital of Xi'an Jiaotong University
2023
Maternal and Child Health Hospital of Sichuan Province
2022
West China Hospital of Sichuan University
2018-2021
Sichuan University
2018-2021
First Affiliated Hospital of University of South China
2015
University of South China
2015
China Medical University
2009
This study aims to evaluate the clinical significance of crescent and global glomerulosclerosis formation on renal outcome in patients with IgA nephropathy (IgAN).Biopsy-proven primary IgAN from West China Hospital Sichuan University were studied retrospectively between 2008 2015. Clinicopathological features treatment modalities recorded. The divided into several groups basis cellular and/or fibrocellular crescents scores scores. Crescent (C) was scored according updated Oxford...
Transforming growth factor-β1 (TGF-β1) signaling and high mobility group A (HMGA1) are known to play essential roles in the progression of breast cancer by inducing epithelial-mesenchymal transition. However, correlation between TGF-β1 HMGA1 cell is not yet well understood. In this study, we determined effects on expression cells examined role progression. Our results demonstrated that induced both MCF-7 MDA-MB-231 cells, as shown RT-qPCR immunofluorescence staining; however, TGF-β1-induced...
Henoch-Schönlein purpura nephritis (HSPN) is a common vasculitis involving the kidneys, with lower incidence in adults. Meanwhile, nephrotic syndrome (NS) can appear HSPN. However, clinicopathological features and renal outcome of adult-onset HSPN presenting NS (NS-HSPN) have not been well clarified.A total 191 patients were prospectively analyzed comparisons made between NS-HSPN non-NS-HSPN. Multivariate Cox regression analysis was carried out to find unfavorable factors NS-HSPN.Among...
Orofacial pain (OFP) is a highly prevalent disorder in mainland China that predisposes to an associated physical and psychological disability. There lack of good properties Chinese version instrument examine OFP. This study aims cross-cultural adaptation evaluate psychometrics the Manchester Pain Disability Scale (MOPDS) Mandarin context.Translation adaption MOPDS were conducted following accepted guidelines self-report measures. college students (N = 1039) completed for item analysis,...
OBJECTIVES: Neutrophil gelatinase-associated lipocalin (NGAL) has been proved as a sensitive biomarker in acute and chronic renal injury. Renal impairment is common complication of multiple myeloma (MM). We attempt to assess the value NGAL for t
The prognosis of brain metastases in non-small cell lung cancer (NSCLC) is poor, and patients with EGFR mutations are more likely to have metastases. epidermal growth factor receptor (EGFR) gene status has changed the direction treatment for NSCLC development tyrosine kinase inhibitors (EGFR-TKI) prolonged survival time should be individualized according clinical symptoms, tumor stage, different mutation status. As heterogeneous at molecular level, related biomarker studies looking...
Abstract Background Immunoglobulin A nephropathy (IgAN) is a common autoimmune glomerular disease, the classic manifestations of which are hematuria and proteinuria. The pathogenesis IgAN has been associated with dysregulated intestinal mucosal immunity. However, whether gut microbial modifications play part in remains unclear. Methods Blood fecal samples were collected from 52 patients 25 healthy controls (HCs). microbiome was analyzed by 16S ribosomal RNA (rRNA) gene sequencing, followed...