In recent years, machine learning methods have been applied successfully in many fields. this paper, three algorithms, including partial least squares-discriminant analysis (PLS-DA), adaptive boosting (AdaBoost), and light gradient (LGBM), were to establish models for predicting the Absorption, Distribution, Metabolism, Excretion, Toxicity (ADMET short) properties, namely Caco-2, CYP3A4, hERG, HOB, MN of anti-breast cancer compounds. To best our knowledge, LGBM algorithm was classify ADMET...

Various tools, such as biomedical manipulators, optical aligners, and ultraprecision manufacturing implement nanopositioners that must be dynamically tunable to satisfy the requirements of different working conditions. In this paper, we present design analysis a flexure-based nanopositioner with characteristics for implementation high-performance servomechanism. The is composed four flexure beams are positioned in parallel symmetric configurations sandwiched between magnetorheological...

Abstract To satisfy the increasing requirements of high-precision and zero-backlash transmission in modern machine tools industrial robots, a precision measurement method roller enveloping hourglass worm tooth surface is demonstrated. The profile modification proposed for meshing, mathematical model standard theoretical actual modified established. deviations are defined, measuring based on gear center. matching analyzed, through establishing evaluation object function designing search...

In order to find out the critical factors on exogenous pathogeny, we classified 2590 disease cases based ID3 decision tree method. Our classification result is acquired by calculating information entropy, conditional entropy and gain, according ldquothe six pathogenic factorsrdquo. process, first gained a set of basic affection filtering pre-process methods. And then established with factors. Finally, transformed into production rules support diagnostic system.

The quantification of the uncertainty and ambiguity factors in management study is significant but difficult. In order to quantify these factors, original Market Quiz Method modified a new method called improved put forward. Method, procedure for application given as well. This novel has been applied analyze telework team based on experiments it shows good effect.

Excitation–emission matrix (EEM) fluorescence spectroscopy has been applied to many fields. In this study, a simple method was proposed obtain the new constructed three-dimensional (3D) EEM spectra based on original spectra. Then, application of N-PLS 3D quantify target compounds in two complex data sets. The quantitative models were established external sample sets and validated using statistical parameters. For validation purposes, obtained results compared with those by applying PLS...

The powder metallurgy database is a data system for effective management of information. With the development information technology, its construction scale and quality will directly affect convenient inquiry information, selection gear materials, research engineering application micro-drive systems, have significance market value. However, groundwork in this field still lags behind other materials fields needs to be developed systematically. Consider small modulus gear’s elastic modulus,...

Improving the utilization efficiency of agricultural water resources (AWRUE) in major grain-producing areas (MGPA) is an effective means to ensure grain production.Using a DEA model and ESDA, this study explored temporal spatial characteristics AWRUE main middle reaches Yangtze River (MRYR) from 2006 2020 analyzed influencing factors via Tobit model.The results indicate that (1) 2020, comprehensive was 0.733, which at high level but not as DEA; (2) showed characteristic "high northwest low...

With the help of DEMATEL method and cross-reinforced matrix method, this paper firstly makes some improvements to analytical hierarchy process (AHP), then provides a hierarchical model for member selection telework teams, finally designs fuzzy management experiment under network environment. The modified AHP is used determine weights criteria, comprehensive evaluation assess suitability experimental candidates. improved can enhance efficiency, effectiveness scientificalness teams.

The powder metallurgy database is a data system for effective management of information. With the development information technology, its construction scale and quality will directly affect convenient inquiry information, selection gear materials, research engineering application micro-drive systems, have significance market value. However, groundwork in this field still lags behind other materials fields needs to be developed systematically. Consider small modulus gear’s elastic modulus,...

<p> </p> <p>The powder metallurgy database is a data system for effective management of information. With the development information technology, its construction scale and quality will directly affect convenient inquiry information, selection gear materials, research engineering application micro-drive systems, have significance market value. However, groundwork in this field still lags behind other materials fields needs to be developed systematically.</p>...