A5063993431- Metabolomics and Mass Spectrometry Studies
- Analytical Chemistry and Chromatography
- Natural product bioactivities and synthesis
- Traditional Chinese Medicine Analysis
- Analytical Methods in Pharmaceuticals
- Analytical chemistry methods development
- Electrochemical sensors and biosensors
- Ginseng Biological Effects and Applications
- Medicinal Plant Pharmacodynamics Research
- Pharmacological Effects of Natural Compounds
- Traditional Chinese Medicine Studies
- Carbon and Quantum Dots Applications
- Phytochemistry and Biological Activities
- Pharmacological Effects and Assays
- Antibiotics Pharmacokinetics and Efficacy
- Advanced biosensing and bioanalysis techniques
- Bone Metabolism and Diseases
- Molecular Sensors and Ion Detection
- Hormonal and reproductive studies
- Plant-based Medicinal Research
- Nanocluster Synthesis and Applications
- Mass Spectrometry Techniques and Applications
- Chromatography in Natural Products
- Tryptophan and brain disorders
- Drug-Induced Hepatotoxicity and Protection
Shenyang Pharmaceutical University
2016-2025
Hubei University of Chinese Medicine
2023-2025
Hubei University
2025
Hubei Provincial Hospital of Traditional Chinese Medicine
2025
The University of Texas at Austin
2024
Huanggang Normal University
2015
Inha University
2013
Stony Brook University
2004
State University of New York
2004
Background Renal fibrosis is a hallmark and the final outcome of chronic kidney disease (CKD). Jingtian Granule (JT), traditional formula used in clinical treatment CKD for many years. However, mechanism action JT against renal interstitial remain unknown. Objective This study aimed to explore potential effects mechanisms on adenine - diet induced mice. Methods was mice by treated with JT. function assessed measuring blood urea nitrogen serum creatinine levels. Masson’s staining type I...
Abstract This paper describes the pharmaco‐metabonomic study on Epimedium brevicornum Maxim. treated rats with a pathologic condition similar to ‘kidney deficiency syndromes’ in traditional Chinese medicine and its therapeutic basis. UPLC‐MS technique was used for development of chemical profile endogenous metabolite profiles pre‐ post‐hydrocortisone interfered this herbal medicine. The comparison among performed statistical technique, principle component analysis (PCA). Significant...
ABSTRACT A simple, specific and sensitive ultra‐performance liquid chromatography tandem mass spectrometry (UPLC‐MS/MS) method was established validated for simultaneous determination of neochlorogenic acid, chlorogenic cryptochlorogenic acid geniposide in rat plasma using puerarin as an internal standard (IS). Plasma samples were pretreated by a one‐step direct protein precipitation procedure with acetonitrile after acidified little 50 μL plasma. Chromatographic separation performed on...
The DES combined with UAE was first successfully applied in simultaneously extracting five bioactive flavonoids <italic>Radix scutellariae</italic>.