A5036571201- Health disparities and outcomes
- Chronic Disease Management Strategies
- Colorectal Cancer Screening and Detection
- Cancer-related molecular mechanisms research
- Health, psychology, and well-being
- Epigenetics and DNA Methylation
- Genetic factors in colorectal cancer
- Cervical Cancer and HPV Research
- Gastric Cancer Management and Outcomes
- Global Cancer Incidence and Screening
- Cancer-related gene regulation
- HIV, Drug Use, Sexual Risk
- Ferroptosis and cancer prognosis
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Endometrial and Cervical Cancer Treatments
- RNA modifications and cancer
- Cancer Risks and Factors
- Genetic Associations and Epidemiology
- Health Systems, Economic Evaluations, Quality of Life
- HIV/AIDS Research and Interventions
- Cancer, Lipids, and Metabolism
- Adolescent Sexual and Reproductive Health
- Pancreatic and Hepatic Oncology Research
- Health and Well-being Studies
Second Affiliated Hospital of Zhejiang University
2021-2022
Zhejiang University
2016-2021
Cervical cancer is 1 of the most common cancers in females worldwide. Understanding recent global patterns and temporal trends cervical burden might be helpful for its prevention control.Data on (International Classification Diseases, Tenth Revision, code C53) incidence mortality 2018 were extracted from GLOBOCAN database further analyzed their correlations with Human Development Index. Temporal using annual percent change joinpoint analysis among 31 countries highly qualified data Cancer...
Epigenetic alternation is a common contributing factor to neoplastic transformation. Although previous studies have reported cluster of aberrant promoter methylation changes associated with silencing tumor suppressor genes, little known concerning their sequential DNA during the carcinogenetic process. The aim present study was address genome-wide search for identifying potentially important methylated and investigate onset pattern progression colorectal neoplasia. A three-phase design...
This study aimed to investigate the prevalence of depressive symptoms and association between multimorbidity among elderly in eastern China.A multicenter cross-sectional was conducted four cities (Jianggan, Yiwu Anji Zhejiang Province Taixing Jiangsu Province) China. We collected information on 27 chronic conditions through self-reported medical history used Geriatric Depression Scale (GDS) short form evaluate symptoms. Multivariate Logistic regression relationship symptoms.Five thousand two...
Population aging is an inevitable trend and previous studies have showed the relationship between social health related factors health-related quality of life (HR-QOL) in elderly. The objective this study to investigate association status with HR-QOL among community-dwelling elderly Zhejiang.This cross-sectional was based on individuals from July 2018 September Zhejiang, China. measured by 12-item Short-Form Health Survey (SF-12). Social estimated long-form Scale for Elderly (SHSE-L)...
Evidence on the link between healthy lifestyle and colorectal cancer (CRC) precursors is limited. Our study aimed to examine compare associations of with CRC in adenoma (AD)-carcinoma serrated pathways. A total 24 480 participants including 6309 ADs, 1343 polyps (SPs), 16 828 polyp-free controls were included. score (HLS) was constructed based five factors cigarette smoking, alcohol drinking, physical activity, diet body weight, categorized into least, slightly, moderately most healthy....
Sporadic colorectal cancer (CRC) develops principally through the adenoma-carcinoma sequence. Previous studies revealed that DNA methylation alterations play a significant role in neoplastic transformation. On other hand, long noncoding RNAs (lncRNAs) have been identified to be associated with some critical tumorigenic processes of CRC. Accumulating evidence indicates more intricate regulatory relationships between and lncRNAs Nevertheless, at different stages carcinogenesis based on...
Abstract Backgrounds Social Health Scale for the Elderly short version (SHSE-S) is a psychometrically sound instrument that comprehensively assesses social health status of older adults in China. The aim present study was to establish continuous normative data SHSE-S. Methods We conducted multicenter cross-sectional among 31 communities eastern Older aged 60 years and above were invited participate study. Each participant interviewed in-person finish structured questionnaire. SHES-S score...
Abstract Background The novel long noncoding RNA MEF2C-AS1 has been identified to play suppressor roles during tumorigenesis. DNA methylation a regulatory effect on gene expression in cancer initiation and progression. However, the status of its role colorectal (CRC) development remain unclear. Methods levels were systematically analyzed among 31 cancers with available qualified data GEPIA UCSC Xena databases. Then, was firstly examined 12 CRCs by Illumina Infinium MethylationEPIC BeadChip...
Expanding real-name HIV test is the basis of real-time reporting system in China, and it plays an important role for progress. In year 2003, there were 45 092 cases positives reported cumulatively, which accounted only 5.4% estimated population positives. Since implementation establishment, system, up to 2005, total was 577 000, took 67.9% Also among cases, 387 000 have received anti-retroviral treatment. Normalization prevention control will pave way medical insurance It a goal that all...
Objective To explore the correlation between obesity and risk of colorectal adenoma, so as to provide theoretic evidence for intervention high-risk population cancer. Methods Based on Screen Project Early Diagnosis Treatment Colorectal Cancer in Jiashan County, from August 2012 March 2018, results colonoscopy body measurement information cancer were collected. According colonoscopy, 3 895 patients with adenoma 11 232 healthy controls enrolled. Multivariate logistic regression was used...