- Spine and Intervertebral Disc Pathology
- Management of metastatic bone disease
- Spinal Fractures and Fixation Techniques
- Scoliosis diagnosis and treatment
- Sarcoma Diagnosis and Treatment
- Cervical and Thoracic Myelopathy
- Spinal Hematomas and Complications
- Orthopaedic implants and arthroplasty
- Cancer Diagnosis and Treatment
- Pelvic and Acetabular Injuries
- Medical Imaging and Analysis
- Orthopedic Infections and Treatments
- Bone Tumor Diagnosis and Treatments
- Total Knee Arthroplasty Outcomes
- Infectious Diseases and Tuberculosis
- Musculoskeletal pain and rehabilitation
- Hip disorders and treatments
- Neurofibromatosis and Schwannoma Cases
- Shoulder Injury and Treatment
- Bone health and osteoporosis research
- Connective tissue disorders research
- Meningioma and schwannoma management
- Knee injuries and reconstruction techniques
- Venous Thromboembolism Diagnosis and Management
- Aortic Disease and Treatment Approaches
Kanazawa University
2016-2025
Kanazawa University Hospital
2010-2024
Ishikawa Prefectural Central Hospital
2024
Kanazawa Hospital
2022
Nagoya University
2020
Radiation Effects Research Foundation
2020
Clinical Orthopaedics and Related Research
2020
Japan Society for the Promotion of Science
2020
Nagoya City University
2020
Takara (Japan)
2020
surgical techniques.A review of the developmental process this operation leads to recognition tips, pitfalls, and solutions.We here principal concepts TES for spinal tumors, as well their related basic works that support rationality operation. Principal concept Oncologic tumors (compartment barriers)Enneking et al. examined local spread primary bone soft tissue extremities proposed a "surgical staging system" "the compartment anatomic barriers." 17Applying spine, we studied histology 19...
In Brief Study Design. A retrospective review (phase 1) and prospective clinical study 2). Objectives. To identify independent risk factors for surgical site infection (SSI) to evaluate the positive effect of prostaglandin E1 (PGE1) decrease SSI in patients with spinal metastasis. Summary Background Data. Surgery metastasis is associated an increased SSI. Although previous reports have evaluated metastasis, most studies lack multivariate analysis. recent demonstrated utility PGE1 decreasing...
Thyroid carcinoma generally has a favorable prognosis, and patients rarely present with distant metastases. Authors of several studies have proposed piecemeal resection for spinal metastases in thyroid carcinoma; however, few analyzed the impact local curative surgery such as total en bloc spondylectomy (TES) carcinoma. The purposes study are to determine strategy surgical treatment evaluate results prognosis associated TES.Twenty-four cases were retrospectively reviewed. included 16 women 8...
Retrospective study of registry data.Aging society and recent advances in surgical techniques general anesthesia have increased the demand for spinal surgery elderly patients. Many complications been described patients, but a multicenter perioperative patients aged 80 years or older has not reported. Therefore, goal was to analyze associated with spine cervical, thoracic, lumbar lesions.A performed who underwent 262 surgeries at 35 facilities. The frequency severity were examined...
Previous studies have indicated that trunk muscle strength decreases with chronic low back pain, and is associated poor balance, functional performance, falls in older adults. Strengthening exercises for pain are considered the most effective intervention to improve outcomes. We developed an innovative exercise device abdominal muscles also measures strength. The correlation between weakness, as measured by our device, presence of decreased physical ability a risk falling were evaluated...
In Brief Study Design. Circumspinal decompression with dekyphosis stabilization was prospectively performed thoracic myelopathy due to ossification of posterior longitudinal ligament (OPLL). Neurologic outcome reviewed. Objective. To evaluate how easily, safely, and completely the OPLL can be removed or floated by circumspinal stabilization. Summary Background Data. Anterior is best for spinal cord recovery treat caused on concave side cord. However, anterior approach removal plaque...
Segmental arteries including the level of Adamkiewicz artery were interrupted bilaterally for up to 4 levels study effects on spinal cord blood flow and neurologic function in dogs.To examine how many ligations bilateral segmental cause ischemic dysfunction.Interruption at >or=5 consecutive without has been reported risk producing dysfunction dog model. However, ligating have not elucidated.The 25 dogs which originated from L5 taken this study. There 15 divided into 5 groups: sham group, no...
Ten patients with a spinal tumor of the lower lumbar spine underwent total en bloc spondylectomy (TES) by combined posterior-anterior approach. The oncological and neurologic results are analyzed.To describe surgical technique evaluate clinical outcome this surgery.TES at is technically challenging because its anatomy such as presence major vessels lumbosacral plexus nerves.Six aggressive benign tumors 4 solitary metastases involving L4 or L5 were treated. approache operative procedure...
Several studies have evaluated the efficacy of preoperative embolization in devascularizing tumors. However, no study has measured intraoperative blood loss a single palliative surgery compared with control group without embolization. The purpose this retrospective was to evaluate on decompression and instrumented using posterior approach for spinal metastasis. Between 2000 2010, forty-six patients underwent metastasis thoracic lumbar spine. Preoperative performed 23 (embolization group),...
In Brief Study Design. Prospective clinical study. Objective. To identify the incidence and risk factors for venous thromboembolism (VTE) associated with degenerative spinal surgery procedures at different levels various pathologies. Summary of Background Data. Spinal includes treatment pathologies levels. There have been no studies on VTE after respect to screening patients both deep thrombosis pulmonary (PE). Methods. We prospectively investigated occurrence in 459 who were divided into 5...
Retrospective database analysis.Spine surgeries in elderly patients have increased recent years due to aging of society and advances surgical techniques, postoperative complications become more a concern. Postoperative delirium is common complication that impairs recovery increases morbidity mortality. The objective the study was analyze associated with spine surgery aged 80 or older cervical, thoracic, lumbar lesions.A retrospective multicenter performed 262 age who underwent at 35...
In advanced non-small-cell lung cancer (NSCLC), immune checkpoint inhibitors (ICIs) have been reported a better treatment outcome on primary lesions, however, the therapeutic effect bone metastases has not clarified. This study investigates of ICIs in NSCLC.The data patients with NSCLC, treated from 2016 to 2019 at our hospital, were analyzed. The effects and metastatic concomitant use modifying agents (BMA), outcomes, frequency immune-related adverse events (irAEs) skeletal-related (SREs)...
In Brief Study Design. A retrospective review of patients with interruption the artery Adamkiewicz during total en bloc spondylectomy (TES). Objective. To assess neurologic function after in TES. Summary Background Data. The most important feeding thoracolumbar spinal cord is great anterior radiculomedullary artery, also called Adamkiewicz. supplies lower two-thirds via artery. It naturally believed among spine surgeons that surgeries absolutely contraindicated. However, it necessary to...
The prognosis in patients with a distant spinal metastasis from the lung is dismal. role of radical surgery such cases has been questioned because excessive morbidity, blood loss, and operative time as well tumor's extreme malignancy. purpose this study was to evaluate surgical results associated for cancer spine carefully selected clarify whether there an indication total en bloc spondylectomy (TES) metastasis.The author performed retrospective review treated by TES during 10-year period....
Total en bloc spondylectomy (TES) is associated with a high complication rate because it technically demanding and involves patients compromised by cancer. Specifically, perioperative complications are more likely to occur in receiving preoperative irradiation. We examined the TES irradiation.Seventy-seven underwent between May 2010 April 2013. performed retrospective review of prospectively collected data for 50 metastatic tumors thoracic spine, excluding primary spinal tumors, lumbar...
Retrospective clinical study.To assess the and radiological outcome of spinal reconstruction after total en bloc spondylectomy (TES) at 3 or more levels.There have been few reports multilevel for tumor. This is first case series on reconstructions levels TES.Twenty-six patients treated by TES Kanazawa University Hospital were included in this analysis. Reconstruction was performed with pedicle screw fixation a titanium mesh cage filled autograft all cases. To increase stability...
For spinal fusion or the correction of spine deformity at multiple levels, intraoperative rod contouring is required to realign spine. A French bender most common tool used. There are several reports on mechanical properties various rods with manufactured straight rod; however, few describe changes in a rod's after contouring. The authors investigated influences strength and stiffness. 3-point bending test was conducted. Each 18-cm loaded rate 10 mm/min load applicator. Three different...
Metastasectomy of spinal lesions from renal cell carcinoma (RCC) is a promising strategy. However, its clinical outcome after metastasectomy unknown owing to the difficulty curative surgical resection. This first study examine survival rates patients who underwent solitary metastases RCC.A retrospective cohort 36 consecutive with RCC nephrectomy and complete removal between 1995 2010 at our institution. Cancer-specific (CSS) time death or last follow-up was main endpoint. Potential factors...
This was a retrospective clinical study.This study aimed to evaluate our institution's experience with total en bloc spondylectomy (TES) in patients treated for primary lumbar spine tumors and investigate postoperative outcomes.TES is widely accepted by spinal musculoskeletal surgical oncologists results favorable health-related quality of life outcomes. However, this procedure still imposes major risks complications.The cases TES performed between 1993 2015 were retrospectively analyzed....
Aims To evaluate the perioperative complications associated with total en bloc spondylectomy (TES) in patients spinal tumours, based on extent and level of tumour resection. Methods In total, 307 who underwent TES a single centre were reviewed retrospectively. There 164 male 143 female mean age at time surgery 52.9 years (SD 13.3). A 225 operated for metastases, 34 malignant primary tumour, 41 an aggressive benign seven unknown origin. The main lesion was located thoracic spine 213, lumbar...