A5034804236- Spine and Intervertebral Disc Pathology
- Musculoskeletal pain and rehabilitation
- Spinal Fractures and Fixation Techniques
- Pain Mechanisms and Treatments
- Scoliosis diagnosis and treatment
- Cervical and Thoracic Myelopathy
- Orthopaedic implants and arthroplasty
- Bone health and osteoporosis research
- Medical Imaging and Analysis
- Anesthesia and Pain Management
- Pelvic and Acetabular Injuries
- Bone and Joint Diseases
- Advanced Neuroimaging Techniques and Applications
- Orthopedic Infections and Treatments
- Peripheral Nerve Disorders
- Hip disorders and treatments
- Nerve injury and regeneration
- Hip and Femur Fractures
- Osteoarthritis Treatment and Mechanisms
- Spinal Hematomas and Complications
- Bone health and treatments
- Shoulder Injury and Treatment
- Periodontal Regeneration and Treatments
- Inflammatory mediators and NSAID effects
- Total Knee Arthroplasty Outcomes
Chiba University
2016-2025
Chiba University Hospital
2011-2024
Karolinska University Hospital
2023
Open Evidence
2022
Level (Czechia)
2022
Kitasato Institute Hospital
2020
Kitasato University
2011-2020
Orthopedic One
2017
Teikyo University Chiba Medical Center
2011-2015
Naito Foundation
2014
Prospective study.To examine the efficacy of teriparatide or bisphosphonate treatment to reduce pedicle screw (PS) loosening after instrumented lumbar posterolateral fusion in postmenopausal women with osteoporosis.Failure fixation caused by PSs osteoporosis is a problem spinal surgery. Oral administration intermittent injection parathyroid hormone increases bone mass and reduces risk osteoporotic vertebral fractures. Although these treatments may be factor improving quality, clinical study...
A retrospective multicenter survey.To investigate the perioperative complications of oblique lateral interbody fusion (OLIF) surgery.OLIF has been widely performed to achieve minimally invasive, rigid lumbar fusion. The associated are not yet well described.The participants were patients who underwent OLIF surgery under diagnosis degenerative diseases between April 2013 and May 2015 at 11 affiliated medical institutions. collected data classified into intraoperative early-stage postoperative...
The exact mechanism of knee osteoarthritis (OA)-associated pain is unclear, whereas mixed evidence inflammatory and neuropathic has been noted. We aimed to investigate pain-related sensory innervation in a monoiodoacetate (MIA)-induced model OA.Sixty seventy female Sprague Dawley rats six week-old underwent intra-articular MIA fluorogold (FG) retrograde neurotracer injection into their right (ipsilateral) knee, while left knees were treated with FG saline as control (contralateral knee)....
In Brief Study Design. Prospective trial. Objective. To examine the clinical efficacy of teriparatide for bone union after instrumented lumbar posterolateral fusion using local grafting in women with postmenopausal osteoporosis. Summary Background Data. Intermittent parathyroid hormone (PTH) treatment increases mass and reduces risk osteoporotic vertebral fractures. Recombinant human PTH (1–34) has already been approved as a severe Preclinical data support spinal fusion. However, results...
One of the sources knee pain in osteoarthritis (OA) is believed to be related local chronic inflammation joints, which involves production inflammatory cytokines such as tumor necrosis factor alpha (TNFα), interleukin (IL)-6, and nerve growth (NGF) synovial membrane, these are promote pathological OA. In present study, correlations between proinflammatory fluid radiographic changes functional scores among OA patients were examined. Synovial was harvested from knees 47 consecutive patients,...
Surgery for lumbar spinal degeneration disease is widely performed. While posterior decompression and fusion are popular, anterior interbody (ALIF) also used treatment. Extreme lateral (XLIF) commonly noninvasive ALIF; however, several complications, such as nerve psoas muscle injury, have been reported. In the current study, we examined clinical efficacy complications of oblique (OLIF) disease.Thirty-five patients with degenerated spondylolisthesis, discogenic pain, kyphoscoliosis were...
Pain from osteoarthritis (OA) is generally classified as nociceptive (inflammatory). Animal models of knee OA have shown that sensory nerve fibers innervating the are significantly damaged with destruction subchondral bone junction, and induce neuropathic pain (NP). Our objective was to examine NP in knees patients using painDETECT (an questionnaire) evaluate relationship between NP, intensity, stage OA.Ninety-two were evaluated this study. scores Visual Analogue Scales (VAS), Western...
The importance of pelvic incidence-lumbar lordosis (PI-LL: PI minus LL) mismatch is emphasized in long-segment fusion for adult spinal deformity; however, there are few studies evaluating the influence PI-LL on surgical outcomes after short-segment fusion. In this study, we have examined effects lumbar intervertebral degenerative diseases. Patients with disease treated by (1 or 2 levels) transforaminal interbody were divided into Group A (PI-LL ≤ 10°: n = 22) and B ≥ 11°: 30). Pre-and...
Prospective case series.To examine the clinical efficacy of mini-open anterior retroperitoneal lumbar interbody fusion: oblique lateral fusion (OLIF) for degenerated spinal kyphoscoliosis.The existing surgical procedures treatment kyphotic deformity, including Smith-Petersen osteotomy, pedicle subtraction and vertebral column resection procedures, are invasive in nature. Extreme to provide less deformity has been reported, but complications nerve psoas muscle injury have noted. In current...
Randomized, controlled study.To evaluate the diagnosis of discogenic low back pain (LBP) with discography and discoblock.Discogenic LBP is usually diagnosed by magnetic resonance imaging discography. However, reliability controversial. Previously, we reported usefulness discoblock bupivacaine for diagnosis, improved results anterior interbody fusion surgery. that study was not a randomized, study. Therefore, purpose current to compare surgery after discoblock.Patients (n = 42) severe showing...
<h3>BACKGROUND AND PURPOSE:</h3> DTI can provide valuable structural information that may become an innovative tool in evaluating lumbar foraminal nerve root entrapment. The purpose of this study was to visualize the roots and measure their FA healthy volunteers patients with stenosis by using tractography 3T MR imaging. <h3>MATERIALS METHODS:</h3> Eight 8 underwent In all subjects, performed echo-planar imaging at a b-value 800 s/mm<sup>2</sup> were visualized tractography. Mean values...
Prospective randomized trial.To examine the effect of tumor necrosis factor alpha (TNF-α) inhibitor, etanercept, on radicular pain by its epidural administration onto spinal nerves in patients with lumbar stenosis.TNF-α is thought to play a crucial role caused disc herniation and stenosis. Intravenous infusion infliximab for sciatica has been examined 2 studies; however, results were equivocal.Eighty low back leg investigated. We diagnosed physical examination, X-ray magnetic resonance...
Immunohistological analysis in an injured intervertebral disk (IVD) model.To elucidate and compare rats the behavior of sensory nervous system inflammatory mediators experimentally IVDs.Multiple human animal studies have verified presence nerve fibers IVDs or investigated IVDs, but no vivo study to date has examined relationship between 2.Eight-week-old female were used. In disk-injured group, L5/L6 disks with a 24-gauge needle; simultaneously, neurotracer Fluoro-gold was injected into IVD....
Object Many surgeons currently prefer to use transforaminal lumbar interbody fusion (TLIF), placing 1 unilateral pedicle screw (PS) and cage. However, no study has examined whether fixation improves surgical outcome. The authors conducted a prospective randomized controlled trial with minimum 2-year follow-up analyze TLIF outcomes for 2 techniques: placement of PS cage compared bilateral PSs cages. Methods Fifty patients degenerative spondylolisthesis undergoing single-level were randomly...
Retrospective study of registry data.Aging society and recent advances in surgical techniques general anesthesia have increased the demand for spinal surgery elderly patients. Many complications been described patients, but a multicenter perioperative patients aged 80 years or older has not reported. Therefore, goal was to analyze associated with spine cervical, thoracic, lumbar lesions.A performed who underwent 262 surgeries at 35 facilities. The frequency severity were examined...
Age-related sarcopenia can cause various forms of physical disabilities. We investigated how affects degenerative lumbar scoliosis (DLS) and spinal canal stenosis (LSCS).Subjects comprised 40 elderly women (mean age 74 years) with disease whose chief complaints were low back pain lower limb pain. They included 15 cases DLS 74.8 25 LSCS 72.9 years). performed whole-body dual-energy X-ray absorptiometry (DXA) to analyze body composition, including appendicular trunk skeletal muscle mass index...
Abstract Lumbar spondylolysis generally occurs in adolescent athletes. Bony union can be expected with conservative treatment, however, the fracture does not heal some cases. When becomes a pseudoarthrosis, patients have potential to develop isthmic spondylolisthesis. A cross-sectional study was performed determine incidence of and spondylolisthesis, elucidate when how often spondylolisthesis or without spondylolysis. Patients undergoing computed tomography (CT) scans abdominal lumbar...
(2020). Automated classification of hip fractures using deep convolutional neural networks with orthopedic surgeon-level accuracy: ensemble decision-making antero-posterior and lateral radiographs. Acta Orthopaedica: Vol. 91, No. 6, pp. 699-704.
Objective: In recent years, there has been an increase in research on the therapeutic effects of exergaming, but have few studies these types interventions for chronic low back pain. this study, we hypothesized that Nintendo Ring Fit Adventure (RFA) exergame would be effective patients with pain, and conducted a randomized prospective longitudinal study. Materials Methods: Patients pain were included Twenty randomly selected (9 males 11 females, mean age 49.3 years) RFA group, exergaming was...