A5020163990- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Scoliosis diagnosis and treatment
- Cervical and Thoracic Myelopathy
- Musculoskeletal pain and rehabilitation
- Pelvic and Acetabular Injuries
- Medical Imaging and Analysis
- Spondyloarthritis Studies and Treatments
- Bone health and osteoporosis research
- Spinal Hematomas and Complications
- Nutrition and Health in Aging
- Orthopaedic implants and arthroplasty
- Hip and Femur Fractures
- Rheumatoid Arthritis Research and Therapies
- Bone Tissue Engineering Materials
- Spinal Dysraphism and Malformations
- Management of metastatic bone disease
- Bone health and treatments
- Plasma and Flow Control in Aerodynamics
- Balance, Gait, and Falls Prevention
- Hip disorders and treatments
- Plasma Applications and Diagnostics
- Cerebral Palsy and Movement Disorders
- Anesthesia and Pain Management
- Pregnancy-related medical research
Tokyo Metropolitan University
2022-2025
Osaka Metropolitan University
2022-2025
Osaka City University
2014-2024
Metropolitan University
2024
Osaka City University Hospital
2019
Osaka City General Hospital
2007-2008
Ministry of Education, Culture, Sports, Science and Technology
2005
Although bone morphogenetic proteins (BMPs) are clinically useful for regeneration, large amounts required to induce new formation in monkeys and humans. We found recently that heparin stimulates BMP activity vitro (Takada, T., Katagiri, Ifuku, M., Morimura, N., Kobayashi, Hasegawa, K., Ogamo, A., Kamijo, R. (2003) J. Biol. Chem. 278, 43229-43235). In the present study, we examined whether enhances induced by BMPs vivo attempted determine molecular mechanism which using C2C12 myoblasts....
A prospective observational study.To evaluate the paravertebral muscle (PVM) degeneration in patients with degenerative lumbar scoliosis (DLS), using magnetic resonance imaging.Several studies have described histological and morphological changes to PVM chronic low back pain radiculopathy. However, there is little knowledge about DLS.Fifty-seven spinal stenosis (LSS) DLS (DLS group) 50 control LSS without (LSS were examined. The cross-sectional area (CSA) percentage of fat infiltration...
Abstract The anatomical structure at bone‐tendon and bone‐ligament interfaces is called the enthesis. Histologically, enthesis characterized by a transitional series of tissue layers from end tendon to bone, including tendon, fibrocartilage, calcified bone. This arrangement yields stronger direct connection soft tissues In surgical repair, has proven difficult reproduce, success ligament‐bone bonding depended on fibrous attachment that forms after any ligament reconstructions. this study, we...
In Brief Study Design. Retrospective review. Objective. Evaluation of the impact diabetes on lumbar spine surgery. Summary Background Data. Characteristics that increase risk postoperative complications and poor surgical outcomes after surgery remain unclear. Methods. The demographic clinical data diabetic nondiabetic patients, 50 years or older, undergoing were reviewed. Japanese Orthopaedic Association visual analogue scale scores for low back pain, leg numbness assessed as perioperative...
A retrospective clinical study.To evaluate the effect of preservation paraspinal muscles attached at spinous process C2 or C7 in selective laminoplasty on postoperative axial pain.Several methods modified such as decompression and/or reconstruction detached have been reported. It is still unclear, however, which posterior need to be preserved reduce problems.The study group consisted 145 patients who underwent cervical laminoplasty. The level was decided based preoperative magnetic resonance...
In Brief Microsurgical bilateral decompression via a unilateral approach provided satisfactory clinical outcome with reoperation rate of 7% over longer than 5-year follow-up. The radiographic changes after this procedure were similar to those described in other reports on the natural course lumbar spinal stenosis and degenerative spondylolisthesis.
More information about the association between preoperative anterior translation of C-7 plumb line and clinical outcomes after decompression surgery in patients with lumbar spinal canal stenosis (LSS) would help resolve problems for sagittal imbalance. The authors evaluated whether alignment spine affects low-back pain microendoscopic laminotomy.This study was a retrospective review prospectively collected surgical data. comprised 88 LSS (47 men 41 women) who ranged age from 39 to 86 years...
Study Design Retrospective cohort study. Objectives Spinal surgeons face a dilemma regarding the continuation or discontinuation of antiplatelet agents during perioperative period. Guidelines recommend considering balance between thrombotic and bleeding risks. However, no consensus exists for use these patients who undergo minimally invasive lumbar decompression. This study aimed to assess effect continued medication on posterior decompression surgery outcomes, focusing outcomes 1-year...
Background/Objective: Anti-tumor effects of plasma-activated medium (PAM) were demonstrated using various malignant tumors. However, the anti-tumor effect PAM on synovial sarcoma remains unclear. Therefore, we aimed to investigate and its underlying mechanisms, focusing quantitative analyses both intracellular reactive oxygen species (ROS) cell apoptosis. Methods: The human line HS-SY-II was used viability after treatment. We investigated side local injection in a xenograft murine model....
Lumbar spinal stenosis (LSS) is one of the most frequent causes low back pain and gait disturbance in elderly. Ligamentum flavum (LF) hypertrophy main pathomechanism LSS, but reason for its occurrence not clearly elucidated. In this study, we established a novel animal model intervertebral mechanical stress concentration investigated biological property LF. The LF with showed degeneration elastic fibres disruption cartilage matrix increase, which are similar to findings hypertrophied from...
OBJECTIVE Little is known about the relationship between sagittal spinal alignment in patients with lumbar canal stenosis (LSS) and objective findings such as spinopelvic parameters, back muscle degeneration, clinical data. The purpose of this study was to identify preoperative radiological factors that predict improvement after decompressive surgery LSS. METHODS records 61 LSS who underwent microendoscopic laminotomy had pre- postoperative data collected were retrospectively reviewed....
A multicenter, prospective, single-arm, intervention study.The aim of this study was to investigate efficacy balloon kyphoplasty (BKP) for acute osteoporotic vertebral fractures (OVFs) in patients with poor prognostic factors.The indications BKP remain unclear. Characteristic magnetic resonance imaging (MRI) findings (high-intensity or diffuse low-intensity area fractured vertebrae on T2-weighted images) were reportedly predictive delayed union.This enrolled 106 MRI who underwent within 2...
Study design. Cross-sectional study. Objective. Validate the diagnostic accuracy of a deep-learning algorithm for cervical cord compression due to degenerative canal stenosis on radiography. Summary Background Data. The diagnosis myelopathy is often delayed, resulting in improper management. Screening tools suspected would help identify patients who require detailed physical evaluation. Materials and Methods. Data from 240 (120 with magnetic resonance imaging 120 age sex-matched controls)...
Study Design: Level 3 retrospective cohort case-control study.Purpose: This study aimed to investigate the risk factors for distal junctional kyphosis (DJK) caused by osteoporotic vertebral fractures following spinal reconstruction surgery, with a focus on sagittal stable vertebra.Overview of Literature: Despite rarity reports DJK in this setting, was reported reduce when lower instrumented vertebra (LIV) extended posterior corrective fixation Scheuermann’s disease.Methods: included 46...