A5020905184- Spine and Intervertebral Disc Pathology
- Musculoskeletal pain and rehabilitation
- Scoliosis diagnosis and treatment
- Spinal Fractures and Fixation Techniques
- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Orthopaedic implants and arthroplasty
- Bone health and osteoporosis research
- Total Knee Arthroplasty Outcomes
- Pain Mechanisms and Treatments
- Cervical and Thoracic Myelopathy
- Medical Imaging and Analysis
- Orthopedic Infections and Treatments
- Sarcoma Diagnosis and Treatment
- Bone health and treatments
- Mechanical Circulatory Support Devices
- Peripheral Nerve Disorders
- Anesthesia and Pain Management
- Pelvic and Acetabular Injuries
- Cardiac pacing and defibrillation studies
- Management of metastatic bone disease
- Cardiovascular Function and Risk Factors
- Nutrition and Health in Aging
- Infectious Diseases and Tuberculosis
- Bone Metabolism and Diseases
Chiba University
2016-2025
Teikyo University Chiba Medical Center
2019-2025
Kurume University
2025
Miwa Hospital
2013-2024
Chiba University Hospital
2018-2024
National Defense Medical College
2015-2023
Chiba Prefectural Sawara High School
2020-2021
University of Tsukuba
2021
Toho University Medical Center Sakura Hospital
2021
Toho University
2021
Fifty patients who had patellar subluxation and thirty control subjects were examined using axial roentgenograms of the patellofemoral joint that made with knee in 30 45 degrees flexion, as well computed tomography scans full extension. The amount lateral tilt was quantitatively assessed angle, described by Laurin et al., congruence Merchant al. In both patients, angle changed significantly when flexed from extension to degrees. difference between groups statistically significant at each...
Recent establishment of a sensitive ELISA system using antibodies against malondialdehyde-modified low density lipoprotein (MDA-LDL) made it possible to determine the circulating oxidized levels. Here, we investigated serum levels MDA-LDL in 62 patients with coronary artery disease (CAD) compared 42 without CAD [groups CAD(+) and CAD(−), respectively], which are adjusted for age, total cholesterol, LDL high triglyceride Serum were 113.4±49.1 IU/L CAD(+), significantly higher than CAD(−)...
We generated double knock-out mice lacking the GM2/GD2 and GD3 synthase gene by mating single mutants, we analyzed abnormal phenotypes of mutant expressing only GM3 ganglioside. observed a refractory skin lesion that appeared primarily on face at 25 weeks after birth or later. Frequent scratching wound sites was in with injury, suggesting it is triggering factor exacerbates injury. This confirmed isolating special cages for metabolic study which injury developed more rapidly. Characteristic...
The aortic regurgitant fraction was estimated noninvasively in 20 patients with regurgitation from systolic and pulmonary volume flow determined by duplex Doppler echocardiography. By assuming that an excess of the (AF) compared (PF) is due to flow, (RF) calculated as follows: RF(%) = (AF - PF)/AF X 100. flows were products integrals ejection velocities cross-sectional areas left right ventricular outflow tracts, respectively. estimate semiquantitative grading (1+ 4+) cineaortography...
The intestinal microbiota may regulate bone metabolism by reducing levels of pro-inflammatory cytokines, and T cells in tissues oestrogen-deficient mice have been reported. Resistant starch (RS) is a type dietary fibre results changes the composition gut microbiota. We evaluated effects RS supplemented diets on microbial composition, mineral density, inflammatory-gene expression colon marrow ovariectomised (OVX) mice. OVX were divided randomly into three groups: control, fed 20% high amylose...
Controlled laboratory study.This study aimed to evaluate the efficacy of platelet-rich plasma (PRP) stored at room temperature (RT), frozen, or after freeze-drying.PRP enriches tissue repair and regeneration, is a novel treatment option for musculoskeletal pathologies. However, whether biological activity preserved during PRP storage remains uncertain.PRP was prepared from blood 12 healthy human volunteers (200 mL/person) using three methods: RT with shaking, frozen -80℃, freeze-dried RT....
Study Design: Retrospective cohort study. Objective: To develop a machine learning (ML) model that predicts the progression of AIS using minimal radiographs and simple questionnaires during first visit. Summary Background Data: Several factors are associated with angle in patients AIS. However, it is challenging to predict angular at Methods: Among female treated single institution from July 2011 February 2023, 1119 cases were studied. Patient data, including demographic radiographic data...
Abstract Purpose This study was designed to develop a machine learning (ML) model that predicts future Cobb angle in patients with adolescent idiopathic scoliosis (AIS) using minimal radiographs and simple questionnaires during the first second visits. Methods Our focused on 887 female AIS who were initially consulted at specialized center from July 2011 February 2023. Patient data, including demographic radiographic data based anterior-posterior lateral whole-spine radiographs, collected...
Background Symptoms of lumbar spinal stenosis (LSS) are associated with changes in blood flow to lower limbs. These can be perceived as temperature variations, which visualized using thermography. We compared the relationship between subjective symptoms LSS and variations before after surgical intervention investigated patient factors. Methods Patients who underwent laminectomy for were included. Plantar was measured preoperatively postoperatively Subjective backgrounds assessed through...
This study aimed to evaluate the effects of romosozumab, a humanized monoclonal antibody, on bone healing and mechanical strength in rat posterolateral lumbar fusion (PLF) model. The primary objective was determine its potential promoting union enhancing structural integrity graft sites, addressing challenges such as pseudarthrosis hardware failure spinal surgeries. These complications are particularly common osteoporotic patients, where compromised quality reduced capacity significantly...
To justify lumbar fusion or stabilization, a quantitative assessment and definition of spinal instability are essential. quantify instability, the tensile stiffness motion segment (vertebra-disc-vertebra) was measured with distractor during decompression surgery. Stiffness indicated by relationship between load displacement two adjacent spinous processes where vertebral spreader suspended. A load-displacement curve recorded at each step surgical fixation while being distracted constant...
This study aimed to evaluate intrarater and interrater reliability when measuring hip abductor strength in the supine position using a hand-held dynamometer (HHD) (Study 1), elucidate relationships between measured values examiners' physical characteristics 2). Three healthy examiners (1 female, 24 y.o. 2 males 23 27 y.o) 12 subjects (6 females, 24.5 ± 2.8 years 6 males, 27.7 3.5 years) participated Study 1, 20 (7 22.3 1.3 13 29.4 8.2 1 male 2. All were hospital employees. Hip was by HHD...
Study Design Cross-sectional observational study. Purpose To compare measurements of appendicular skeletal muscle mass (ASMM) and whole fat (WFM) obtained using dualenergy X-ray absorptiometry (DXA) bioelectrical impedance analysis (BIA) among patients with low back pain (LBP). Moreover, the study investigated correlation between BIA-based ASMM DXA-based bone mineral density (BMD). Overview Literature If reliable, BIA may be a useful alternative to DXA as screening tool for sarcopenia...
Abstract Fresh platelet-rich plasma (PRP) accelerates bone union in rat model. However, fresh PRP has a short half-life. We suggested freeze-dried (FD-PRP) prepared advance and investigated its efficacy vivo . Spinal posterolateral fusion was performed on 8-week-old male Sprague-Dawley rats divided into six groups based the graft materials (n = 10 per group): sham control, artificial (A hydroxyapatite–collagen composite) –alone, autologous bone, + fresh-PRP, FD-PRP preserved 8 weeks, human...